NU7441 (KU-57788) 化学構造
分子量: 413.49

高品質保証

カスタマーフィードバック(4)

Quality Control & MSDS

製品説明

  • Compare DNA-PK Inhibitors
    DNA-PK製品生物活性の比較
  • 研究分野
  • Combination Therapy
    併用療法

製品の説明

生物活性

製品説明 NU7441 (KU-57788)は、14nMのIC50による非常に強力で選択的なDNAPK阻害剤です。
ターゲット DNA-PK
IC50 14 nM [1]
In vitro試験 NU7441 increases the persistence of γH2AX foci after ionizing radiation–induced or etoposide-induced DNA damage. NU7441 (0.5 μM or 1 μM) appreciably increases G2-M accumulation induced by ionizing radiation, etoposide, and doxorubicin in both SW620 and LoVo cells. [2] NU7441 causes persistence of doxorubicin- and ionising radiation-induced DNA double-strand break and also slightly decreases homologous recombination activity DNA-PK-proficient M059-Fus-1 and DNA-PK-deficient M059 J human tumour cells. [3] NU7441 inhibits UV-induced RPA p34 hyperphosphorylation in a dose-dependent manner both in cells lacking and cells expressing polymerase η. [4] NU7441 increases levels of fludarabine-induced γH2AX foci and correspondingly decreased fludarabine-induced cell death in chronic lymphocytic leukemia cells. [5] NU7441 also inhibits mitoxantrone-induced DNA-PKcs autophosphorylation and repair in chronic lymphocytic leukemia cells. [6]
Cell Data
Cell LinesAssay TypeConcentrationIncubation TimeFormulationActivity DescriptionPMID
NCI-H1770 M3X0Umdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2fZeGlEPTB;MD6wNlE1OyEQvF2= M4\UUnNCVkeHUh?=
A172 MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYLJR|UxRTBwMUWzNVYh|ryP Mny2V2FPT0WU
NCI-H526 NV35[JdLT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWLJR|UxRTBwMki0NFch|ryP NIS1XG1USU6JRWK=
HDLM-2 MkfUS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXTJR|UxRTBwM{KzOFUh|ryP NFjNZW9USU6JRWK=
HuO-3N1 MmK3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NH;rflhKSzVyPUCuOFY3OzZizszN NXnHbVZQW0GQR1XS
NCI-SNU-1 MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1zMTGlEPTB;MD62NFk6PCEQvF2= NF7Xd49USU6JRWK=
SK-N-AS MlnFS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWnXV|N[UUN3ME2wMlYzOjF4IN88US=> MoTVV2FPT0WU
LoVo NEW3T|RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVfMRVBiUUN3ME2wMlg3PzR7IN88US=> MVnTRW5ITVJ?
LAMA-84 M4fJdWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mn64TWM2OD1yLkm4PFM{KM7:TR?= Mlv4V2FPT0WU
CTB-1 NEjPS4lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXXJR|UxRTFwMUG1OFYh|ryP MlnGV2FPT0WU
KP-N-YS MXjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXK5UII3UUN3ME2xMlE1OjNzIN88US=> M3\yZXNCVkeHUh?=
HH NX7xS2JUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NF3zbZRKSzVyPUGuNVgxQTNizszN M33jd3NCVkeHUh?=
CHL-1 MYjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIXRXo9KSzVyPUGuNlE{PjhizszN MnjpV2FPT0WU
NB7 NWHmdGhMT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYn4cI9JUUN3ME2xMlI1PzR3IN88US=> NXP6O5J5W0GQR1XS
HL-60 M3vrZ2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXzUZ49tUUN3ME2xMlM5OTlizszN NGDRNnRUSU6JRWK=
639-V M3zmfGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{\xTGlEPTB;MT60OFEzQCEQvF2= M17OO3NCVkeHUh?=
NCI-H1793 M4G2[Wdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkWyTWM2OD1zLkS1PFQh|ryP NWXVUo1uW0GQR1XS
NEC8 MnfZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3Tzd2lEPTB;MT61OVM2KM7:TR?= M4HxfnNCVkeHUh?=
PA-1 NHfJN|lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFL0XotKSzVyPUGuOVgzQTRizszN MlqzV2FPT0WU
D-423MG NF3Qd4NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2nG[GlEPTB;MT62PVM3OSEQvF2= M4rX[XNCVkeHUh?=
NCI-H292 NWjEZ3JGT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUTJR|UxRTFwN{SwNVMh|ryP M2r4[nNCVkeHUh?=
SK-MEL-1 NVjLTGVCT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlLUTWM2OD1zLke5OFc6KM7:TR?= NVzSemw5W0GQR1XS
LB2241-RCC NVvYfo5NT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEjwfYpKSzVyPUKuNVQyPDZizszN M2rxUHNCVkeHUh?=
SK-MEL-3 NU[3PVE1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1zEbGlEPTB;Mj6xOlQ6KM7:TR?= NEPpT4pUSU6JRWK=
MHH-PREB-1 Mn3aS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NELFdVlKSzVyPUKuNVY3ODlizszN NV3yS3Q{W0GQR1XS
BFTC-905 NX32Om13T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYPJR|UxRTJwMU[2PFch|ryP MXfTRW5ITVJ?
Ramos-2G6-4C10 NYf6PWVHT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{mwVWlEPTB;Mj6xPVkxQSEQvF2= NH7XU3RUSU6JRWK=
G-361 M4TSWWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkDLTWM2OD1{LkKxOlgh|ryP M3;JfXNCVkeHUh?=
MOLT-4 NWnqW4NkT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4XKcGlEPTB;Mj6yNVg5QCEQvF2= MnP5V2FPT0WU
DEL Mnz2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHXDZo9KSzVyPUKuN|U2PjRizszN MlTKV2FPT0WU
MV-4-11 NX65cJFOT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXnJR|UxRTJwM{ezPUDPxE1? NGjndWdUSU6JRWK=
SK-NEP-1 MnrIS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVHJR|UxRTJwM{i3PFMh|ryP M1f3TXNCVkeHUh?=
RS4-11 NEHrT2FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWHJR|UxRTJwNU[wNlMh|ryP MlPtV2FPT0WU
HuH-7 MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVfJR|UxRTJwNU[3NFIh|ryP NI\tSVhUSU6JRWK=
A101D NEe0dodIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWXF[49zUUN3ME2yMlYyOzN6IN88US=> NH3j[YZUSU6JRWK=
KG-1 NGXuTItIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoiwTWM2OD1{Lk[3PVI1KM7:TR?= NH\1PW9USU6JRWK=
KALS-1 MkjKS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3LYZWlEPTB;Mj62PVY{OyEQvF2= M4DVN3NCVkeHUh?=
VMRC-RCZ M160dmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmT6TWM2OD1{Lke3N|I5KM7:TR?= NYjHXnlTW0GQR1XS
SK-UT-1 M2HnOWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mn7sTWM2OD1|LkG1N|Eh|ryP NGG2TGVUSU6JRWK=
SW962 NW\Z[GF7T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4DtdWlEPTB;Mz6yNFM2OiEQvF2= MWfTRW5ITVJ?
DBTRG-05MG NHPHWW5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1HNW2lEPTB;Mz6yPFA5PSEQvF2= MYTTRW5ITVJ?
PANC-08-13 MkL5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIXM[WNKSzVyPUOuOFEzPzhizszN NGDUTJlUSU6JRWK=
QIMR-WIL MnTTS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFzrUVJKSzVyPUOuOFE{PDFizszN NEPmPGRUSU6JRWK=
SK-MEL-30 Ml2xS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGrJTJRKSzVyPUOuOFI2QThizszN MXzTRW5ITVJ?
697 NGq0O4tIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXrJR|UxRTNwNES5PVMh|ryP NILRdlhUSU6JRWK=
NY NXvaVJlwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MorITWM2OD1|LkS1NFIzKM7:TR?= MkPnV2FPT0WU
ES7 NYr2XHZDT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGf5XndKSzVyPUOuOFY4OjlizszN MmnXV2FPT0WU
JVM-3 MoPLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIrFZnRKSzVyPUOuOFgxPzdizszN NHi2WXZUSU6JRWK=
U031 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVjZS4xkUUN3ME2zMlU6OzZ6IN88US=> MmH0V2FPT0WU
BHT-101 NIW5c5BIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NH7KelVKSzVyPUOuOVk6QDVizszN Mmf3V2FPT0WU
8305C MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYTnOlU5UUN3ME2zMlYyPzN4IN88US=> M2LQPHNCVkeHUh?=
MG-63 MkPlS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{LicWlEPTB;Mz62NlY4PiEQvF2= NGLoUZNUSU6JRWK=
NOS-1 NXL3cJp5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUXF[HFOUUN3ME2zMlY2OzF{IN88US=> M4L0ZXNCVkeHUh?=
YH-13 M1niZ2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M333bGlEPTB;Mz64O|E5QSEQvF2= MVnTRW5ITVJ?
LXF-289 MmK5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHnNXWtKSzVyPUOuPVExPDFizszN NUTQZlVnW0GQR1XS
GOTO NG\o[VJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWnJTXJtUUN3ME2zMlkyPDlizszN M1z2NHNCVkeHUh?=
EKVX MWnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXrJR|UxRTRwMkK1NlQh|ryP NVPIcmFOW0GQR1XS
CAL-51 NYPLfmFDT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NILvdWRKSzVyPUSuNlQ5PTRizszN NVm4fYJCW0GQR1XS
AN3-CA NEX3eWRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MX7JR|UxRTRwMkW4NVMh|ryP MW\TRW5ITVJ?
IA-LM NILyc3BIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUK0XIhNUUN3ME20MlI4QTN3IN88US=> NHLGPGZUSU6JRWK=
KU-19-19 Mn:yS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWLJR|UxRTRwM{K5NlEh|ryP M3q5WnNCVkeHUh?=
A704 NUXUdG14T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGnHZo1KSzVyPUSuOFA5QDhizszN NXLxNWNIW0GQR1XS
RH-18 NI\kWVFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NX35[WN[UUN3ME20MlQ1QTV|IN88US=> NX;iVFRrW0GQR1XS
IST-MEL1 MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIDvZYJKSzVyPUSuOVgzPjNizszN NGGx[ZhUSU6JRWK=
LU-134-A MmTvS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlzLTWM2OD12LkW5Olg2KM7:TR?= NHnVbXZUSU6JRWK=
SF126 NVzXWYhoT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHrrbZRKSzVyPUSuOlA4OTVizszN MnfjV2FPT0WU
EFO-27 NF6xfJFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4rYdmlEPTB;ND62OlUzPSEQvF2= NXrI[GROW0GQR1XS
SN12C MX3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXnJR|UxRTRwN{G4PVgh|ryP NUXPVVk6W0GQR1XS
L-363 M2HRNWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGjlTnBKSzVyPUSuO|cyOTZizszN NH;td2lUSU6JRWK=
MEL-HO MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEDPW4lKSzVyPUSuO|c6QDlizszN Ml7DV2FPT0WU
TYK-nu MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHTqZZdKSzVyPUSuPFAyOjhizszN NIfUWWtUSU6JRWK=
MDA-MB-415 NXXob3NoT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3yyVWlEPTB;NT6wNFMyPCEQvF2= MorNV2FPT0WU
HCC70 MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWPy[YJLUUN3ME21MlA{QTN7IN88US=> M3r2R3NCVkeHUh?=
IGROV-1 NF7Cb5dIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2r5SGlEPTB;NT6yOVI6OiEQvF2= MYLTRW5ITVJ?
NCI-H1355 M3PLNWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnP2TWM2OD13LkK5OkDPxE1? M{HYUHNCVkeHUh?=
23132-87 NGD5UlFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NV;oWZFNUUN3ME21MlMzODJ2IN88US=> NX\NWlVJW0GQR1XS
NB69 MXjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYTJR|UxRTVwM{K0NkDPxE1? MV\TRW5ITVJ?
HSC-2 NXHKU3kyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1P5c2lEPTB;NT60NVc4OyEQvF2= MYPTRW5ITVJ?
KYSE-410 NH3NS5FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MV3JR|UxRTVwNEe2N|Yh|ryP NInN[JdUSU6JRWK=
GCIY MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEHIZotKSzVyPUWuOVE{PzhizszN MW\TRW5ITVJ?
A427 NFLTPYNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUTJR|UxRTVwNUO2OlEh|ryP NELtSJpUSU6JRWK=
ChaGo-K-1 MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFrnXI5KSzVyPUWuOVY2QTlizszN NFvQTnFUSU6JRWK=
PFSK-1 MV7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Ml7xTWM2OD13Lk[yNVk1KM7:TR?= M4TweHNCVkeHUh?=
MLMA MknSS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{LXTWlEPTB;NT64N|YxPiEQvF2= MnfLV2FPT0WU
RVH-421 NYKzOJc6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVPJR|UxRTZwMEezN|gh|ryP MmnoV2FPT0WU
LB1047-RCC NY\HNY5lT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYTJR|UxRTZwMUe1NlIh|ryP MkjmV2FPT0WU
MHH-NB-11 M3S5U2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{XXZmlEPTB;Nj6zNlczOSEQvF2= M3P0ZXNCVkeHUh?=
J-RT3-T3-5 NGTvfHVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVXJR|UxRTZwNkOyPVEh|ryP MWrTRW5ITVJ?
UM-UC-3 M{jGZ2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MorkTWM2OD14Lk[0N|M1KM7:TR?= NWDuRolxW0GQR1XS
IST-SL1 NYj2S4JvT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M33aVWlEPTB;Nj62PVM3QSEQvF2= MWDTRW5ITVJ?
NB14 NELZeYZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWHDd4pDUUN3ME22Mlc6PzZzIN88US=> MYfTRW5ITVJ?
NBsusSR NXHUVHRrT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXLJR|UxRTZwOEK1NFIh|ryP NYXRV5U{W0GQR1XS
D-263MG NVL6Rmx6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWnJR|UxRTZwOUGwOlgh|ryP NYH4ZlIyW0GQR1XS
NCI-H2347 MX3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{nIeGlEPTB;Nj65N|IyOyEQvF2= M3\R[3NCVkeHUh?=
ES8 M3rLS2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYnxUmd7UUN3ME22Mlk4PTh6IN88US=> M1\ZdnNCVkeHUh?=
786-0 NF7hZ5NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXTz[Hp{UUN3ME23MlA6Pzh4IN88US=> NEP4N4NUSU6JRWK=
EPLC-272H MnrnS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NH36d|dKSzVyPUeuNVYzPDZizszN MmrpV2FPT0WU
CAPAN-1 M3vaO2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFf0SY1KSzVyPUeuNlQ{PTlizszN NYTxN5k{W0GQR1XS
NCI-H82 MXTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mlm5TWM2OD15LkK2OlU6KM7:TR?= Mn;1V2FPT0WU
G-402 MnywS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVLJR|UxRTdwM{CwOVEh|ryP NHXQOWJUSU6JRWK=
SW982 M3W5cGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWPJR|UxRTdwM{CyNFMh|ryP NEL6UFRUSU6JRWK=
OVCAR-4 NHu4WndIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGTTZ3ZKSzVyPUeuN|E{OjhizszN M1XL[nNCVkeHUh?=
KARPAS-299 M2LtZWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlO2TWM2OD15LkOyOlIzKM7:TR?= MVnTRW5ITVJ?
MIA-PaCa-2 MX3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVLrbodHUUN3ME23MlM3QDJ|IN88US=> M2TCN3NCVkeHUh?=
AU565 NIPHV4JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mof6TWM2OD15LkW5PFM{KM7:TR?= NV3GRm1sW0GQR1XS
GAMG NXT4U4g{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmPuTWM2OD15Lk[0NVMyKM7:TR?= MXvTRW5ITVJ?
HuO9 MkT3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn32TWM2OD15LkexO|Q{KM7:TR?= MWXTRW5ITVJ?
ACN MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NX\LUnN7UUN3ME23Mlc1OzNizszN NFP0dplUSU6JRWK=
RO82-W-1 MnPRS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVXJR|UxRTdwN{S1N|Mh|ryP M1zOZ3NCVkeHUh?=
NKM-1 M3vESWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MULJR|UxRTdwN{S5OVUh|ryP NHvhPVZUSU6JRWK=
CAL-12T M3Xke2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmC2TWM2OD15Lkm0N|UzKM7:TR?= NG[3TIhUSU6JRWK=
FADU NYnmWmdmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkXGTWM2OD16LkCzOlU1KM7:TR?= MXfTRW5ITVJ?
NCI-H28 NHe0WpVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NH\YVZlKSzVyPUiuNVY6PjJizszN M1TFNXNCVkeHUh?=
LCLC-97TM1 NHXuU41Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{HVfWlEPTB;OD6yNVEzOiEQvF2= M4jETHNCVkeHUh?=
CHP-134 MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXHJR|UxRThwMkSxPFUh|ryP MmDEV2FPT0WU
HT-1080 MX3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVTJR|UxRThwMkWwPVMh|ryP M2XEO3NCVkeHUh?=
PC-3 MWnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mlr6TWM2OD16LkK3N|kzKM7:TR?= NHW1NYNUSU6JRWK=
SNU-449 Mn;BS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mo\ITWM2OD16LkK3PVMh|ryP MlvLV2FPT0WU
VA-ES-BJ NInaOXVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVnPR4JFUUN3ME24MlM1Pjh4IN88US=> MX;TRW5ITVJ?
HT NFHxd41Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NH3vTnFKSzVyPUiuN|Y1QSEQvF2= NY\jeFdWW0GQR1XS
HOS NIDtU|NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGnpZoJKSzVyPUiuN|c2QDlizszN MUjTRW5ITVJ?
KNS-62 M4jXSGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXrJR|UxRThwM{e3OlIh|ryP M3rjNXNCVkeHUh?=
OAW-42 NXjSWolFT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnHITWM2OD16Lkm1PVY1KM7:TR?= MlPiV2FPT0WU
A549 NWTQOZA4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUC1SIw1UUN3ME25MlA6PjF{IN88US=> MX7TRW5ITVJ?
CAKI-1 NUPaNHlpT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIH0cmNKSzVyPUmuNVY3OSEQvF2= MYrTRW5ITVJ?
HCC1937 NXi2e5A4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVnLZ3VEUUN3ME25MlY6QDZ3IN88US=> MkPLV2FPT0WU
GI-ME-N NH;FU2JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWn3UnhRUUN3ME25MlcxOTN5IN88US=> MnfhV2FPT0WU
DU-4475 MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWLJR|UxRTlwOU[5N|kh|ryP NEDPOYRUSU6JRWK=
EM-2 MofyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVPJR|UxRTFyLkK0NlYh|ryP NXrtfnJFW0GQR1XS
NCI-H1755 MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NV[yOI9tUUN3ME2xNE4zPDJ6IN88US=> MWXTRW5ITVJ?
NCI-H1437 NVnTWmZ7T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoPLTWM2OD1zMD61O|I2KM7:TR?= NF\L[G1USU6JRWK=
VM-CUB-1 M3P0[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1\UcmlEPTB;MUCuOlE3PCEQvF2= MYHTRW5ITVJ?
A2058 Mmj0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MW\JR|UxRTFyLk[0NFQh|ryP NV;2WVZ[W0GQR1XS
BPH-1 M3TscWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIH6cpRKSzVyPUGwMlcyPDVizszN NEjsTVVUSU6JRWK=
NB5 M4nBfGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEKxT21KSzVyPUGwMlc2PTlizszN MVvTRW5ITVJ?
G-401 NIPQU41Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NX;xOVZ2UUN3ME2xNE44PjJ4IN88US=> M{DFR3NCVkeHUh?=
CAL-72 M{ftZ2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHrwZoZKSzVyPUGwMlgxQTRizszN MXvTRW5ITVJ?
SK-MEL-28 MkjDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYfJR|UxRTFyLkiyNFIh|ryP NYnLVFFjW0GQR1XS
C32 M4jV[Wdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkDiTWM2OD1zMD64N|Q4KM7:TR?= Ml7zV2FPT0WU
NCI-H1155 M1HhS2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVHJR|UxRTFyLkizO|Yh|ryP NW\jUpZRW0GQR1XS
BB49-HNC MWHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFvvfppKSzVyPUGwMlg2QDZizszN MkfjV2FPT0WU
GMS-10 NUXFV406T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWfJR|UxRTFyLki5O|Eh|ryP Ml7kV2FPT0WU
K5 M{O1fWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkHXTWM2OD1zMD65NFcyKM7:TR?= MmC4V2FPT0WU
OS-RC-2 M2\KPGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mnr6TWM2OD1zMT6wOVU6KM7:TR?= MWrTRW5ITVJ?
HTC-C3 MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MX;JR|UxRTFzLkC3NVQh|ryP NFfuOndUSU6JRWK=
LB996-RCC MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnrjTWM2OD1zMT6wO|I{KM7:TR?= MXTTRW5ITVJ?
NCI-H1563 MlOyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Moe1TWM2OD1zMT6xNFEyKM7:TR?= Ml3LV2FPT0WU
CAL-54 M3jpc2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MV;JR|UxRTFzLkS4NVEh|ryP MoX2V2FPT0WU
WM-115 MmLGS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3rnPWlEPTB;MUGuOlgzPCEQvF2= MoT2V2FPT0WU
COLO-684 M{\GPGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MV3JR|UxRTFzLkeyOlch|ryP MYDTRW5ITVJ?
HOP-62 NE\2VHNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MonYTWM2OD1zMT63OVA5KM7:TR?= MnXVV2FPT0WU
NCI-H650 NEfuZ3FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnT0TWM2OD1zMT64PVYyKM7:TR?= NXPJR4puW0GQR1XS
TE-11 M2jhb2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGfRfYZKSzVyPUGxMlk{OTVizszN MYfTRW5ITVJ?
COLO-679 NEX0OY5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2[yWGlEPTB;MUGuPVQ3KM7:TR?= NX[3N5hXW0GQR1XS
FTC-133 MlH5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVzJR|UxRTF{LkCwO|Yh|ryP MXnTRW5ITVJ?
D-283MED MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWnkUpV2UUN3ME2xNk4xPTZ7IN88US=> MnH4V2FPT0WU
SK-PN-DW M4HIb2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFvNeWtKSzVyPUGyMlE6ODJizszN M2XIOHNCVkeHUh?=
BALL-1 NFXnO2hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFvVepJKSzVyPUGyMlI3PjJizszN M{fueHNCVkeHUh?=
GT3TKB M4rKcmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlX1TWM2OD1zMj6zNFc1KM7:TR?= M1ixTnNCVkeHUh?=
HOP-92 MlfxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{j0e2lEPTB;MUKuOVI{OyEQvF2= NYrZXndoW0GQR1XS
M14 NEm4PYFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MULJR|UxRTF|LkCzN|Uh|ryP NHj3WG9USU6JRWK=
SKG-IIIa NIX6[Y1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Ml7mTWM2OD1zMz6wOVU1KM7:TR?= MmfuV2FPT0WU
Becker NWjrOFRUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{fsN2lEPTB;MUOuNFU5KM7:TR?= NGHqWmlUSU6JRWK=
ES5 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoHmTWM2OD1zMz6xN|U3KM7:TR?= M3HrfnNCVkeHUh?=
NCI-H2030 MVfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIjCTnRKSzVyPUGzMlIxPjJizszN M3ToSXNCVkeHUh?=
SNU-423 MmXZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUKzPZQ6UUN3ME2xN{4{QDFizszN NVnZeHRLW0GQR1XS
CP50-MEL-B NETaOZdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUHPbFZoUUN3ME2xN{43OjN{IN88US=> NHvDVmVUSU6JRWK=
NCI-H1092 NULLUplyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGC2fnpKSzVyPUGzMlc1PzVizszN NEj3bI1USU6JRWK=
8-MG-BA NGDQOXFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYnJR|UxRTF|Lke1NVMh|ryP M1T2PHNCVkeHUh?=
CAL-27 Mm\vS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{i0Z2lEPTB;MUSuNFczPyEQvF2= M1X4WXNCVkeHUh?=
AGS NXLyUmFXT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWXMbVdSUUN3ME2xOE4yOzF7IN88US=> M3LINXNCVkeHUh?=
MZ2-MEL NXLDZ2JjT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYC1cmk{UUN3ME2xOE4yPDh6IN88US=> MYDTRW5ITVJ?
BFTC-909 MkL4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlLpTWM2OD1zND61NFU2KM7:TR?= MY\TRW5ITVJ?
D-566MG M364Wmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3fKTGlEPTB;MUSuO|cxPiEQvF2= MmO3V2FPT0WU
MZ7-mel M3zjT2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHHqTXJKSzVyPUG1MlExPjdizszN MVfTRW5ITVJ?
TE-5 NIHEdY1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M33nXmlEPTB;MUWuNlM{OyEQvF2= NX7SXVBjW0GQR1XS
647-V NHzjUJZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnTNTWM2OD1zNT6yO|A2KM7:TR?= M{Hrb3NCVkeHUh?=
DMS-114 M3G2SGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkXFTWM2OD1zNT6zNlkyKM7:TR?= NUXFN|JbW0GQR1XS
ME-180 MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mn6yTWM2OD1zNT60O|g{KM7:TR?= MnzkV2FPT0WU
MS-1 MoX1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHTBbJFKSzVyPUG1MlU3OjNizszN NEfkcWdUSU6JRWK=
NUGC-3 MV7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3HvcGlEPTB;MUWuOlI1PSEQvF2= MVvTRW5ITVJ?
GB-1 NGXDZ29Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWjJR|UxRTF3Lk[0N|ch|ryP MXnTRW5ITVJ?
LOXIMVI NUPoZVlyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmK0TWM2OD1zNT64PVE6KM7:TR?= NIDjVJBUSU6JRWK=
NCI-H1304 NUK3[nMzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnuwTWM2OD1zNT64PVI5KM7:TR?= MlfVV2FPT0WU
KURAMOCHI M3XRd2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVnXRlBoUUN3ME2xOU46PzFizszN M13NOnNCVkeHUh?=
SW1783 MnzVS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnvSTWM2OD1zNj6wPVk{KM7:TR?= NES5PIZUSU6JRWK=
EGI-1 MmDXS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mlz5TWM2OD1zNj61N|Y2KM7:TR?= M2nPcXNCVkeHUh?=
KGN M2jMS2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWPGNYdYUUN3ME2xOk42PTh4IN88US=> NUPjSm5SW0GQR1XS
PANC-03-27 NGPYT5FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3TkVWlEPTB;MU[uO|Y3OiEQvF2= MmXEV2FPT0WU
RH-1 MlntS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEnoTXdKSzVyPUG2MlgzPSEQvF2= NGT2WmRUSU6JRWK=
HT-1376 M4HOWmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlXnTWM2OD1zNj64OFQ3KM7:TR?= NWnJ[GNUW0GQR1XS
ZR-75-30 MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFvSPHNKSzVyPUG2Mlk{PjFizszN MYHTRW5ITVJ?
TI-73 MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEnXSYxKSzVyPUG2Mlk1ODhizszN M4HsfHNCVkeHUh?=
TK10 M2PzRWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWPJR|UxRTF5LkCwO|kh|ryP MoXZV2FPT0WU
SW684 MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXO3eXRoUUN3ME2xO{4xOTV2IN88US=> M{HzdXNCVkeHUh?=
RPMI-8866 NVr1OW1OT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUjJR|UxRTF5LkC2PVkh|ryP M1TYb3NCVkeHUh?=
LNCaP-Clone-FGC MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWG5OoVmUUN3ME2xO{42OjBzIN88US=> NEOyTmlUSU6JRWK=
NCI-H2291 Ml;yS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3LVUGlEPTB;MUiuOFM1PSEQvF2= NVTPc5pPW0GQR1XS
T47D MlHRS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NV3wcoFmUUN3ME2xPE41QDhizszN NVPy[3M4W0GQR1XS
A204 M2rncmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{\yXWlEPTB;MUiuOVQ2OiEQvF2= M3zSbHNCVkeHUh?=
HT-144 MXzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYTJR|UxRTF6Lke0Nlch|ryP MnjxV2FPT0WU
MDA-MB-361 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVXJR|UxRTF7LkC3NVQh|ryP NXXFO5gxW0GQR1XS
HCC1806 NEnaTXNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3PlZ2lEPTB;MUmuNVU6OSEQvF2= NXvJeG1zW0GQR1XS
NCI-H596 M4XIXmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEHkXlZKSzVyPUG5MlY{QTFizszN NYrrXo5lW0GQR1XS
K-562 NUnsSnZuT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoXnTWM2OD1zOT64PVI3KM7:TR?= NYnxc3NGW0GQR1XS
D-336MG MoflS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1LVWGlEPTB;MUmuPVMzOiEQvF2= NETxTZNUSU6JRWK=
SK-MEL-2 NGnnXXRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVnocHh6UUN3ME2yNE4yPTV7IN88US=> MYrTRW5ITVJ?
HEC-1 M2XJXGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHP0XWxKSzVyPUKwMlQ6PzhizszN M{P1SXNCVkeHUh?=
EW-13 MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MX3JR|UxRTJyLkW0OFMh|ryP MonGV2FPT0WU
Hs-578-T Mmn5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXqwcHhkUUN3ME2yNE42PTh|IN88US=> NWe0bYJYW0GQR1XS
SJSA-1 MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4DHe2lEPTB;MkCuOVY5QCEQvF2= MWHTRW5ITVJ?
RCC10RGB MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFXWVmlKSzVyPUKwMlY4OTlizszN NV;BV45IW0GQR1XS
LAN-6 NVTFVYxQT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnLWTWM2OD1{MT6wN|k3KM7:TR?= MmK2V2FPT0WU
NCI-H1048 MnHWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NU\lVYFbUUN3ME2yNU4zOjV6IN88US=> NWrTXIVLW0GQR1XS
CW-2 NHPWO3VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmXsTWM2OD1{MT6yO|A2KM7:TR?= MXvTRW5ITVJ?
HCC2157 NUDnR5M4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2n0fGlEPTB;MkGuN|Yh|ryP M3\HPHNCVkeHUh?=
EW-22 NX3ac5B5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVPuXm9OUUN3ME2yNU4{PzZizszN MUXTRW5ITVJ?
A253 NGWxdo1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NH74cGNKSzVyPUKxMlQ1QDFizszN NFvpN5BUSU6JRWK=
BE-13 MmPmS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MX3JR|UxRTJzLk[xNVMh|ryP NWXpNnFYW0GQR1XS
KINGS-1 MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mk\6TWM2OD1{MT62N|E3KM7:TR?= NG\FNJJUSU6JRWK=
ETK-1 NX7L[297T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHHwbGtKSzVyPUKxMlgyPTJizszN NUnUZYhMW0GQR1XS
NCI-H2452 NIewN4dIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NITkeI1KSzVyPUKxMlg3PDdizszN M1H6XnNCVkeHUh?=
HPAF-II NX\HSINXT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4n2bmlEPTB;MkGuPFkzOyEQvF2= MnnSV2FPT0WU
D-542MG M4PMWWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUHJR|UxRTJzLkmwOlkh|ryP M1XkZnNCVkeHUh?=
NCI-H630 NVjS[nJ6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWfJR|UxRTJ{LkCyPVYh|ryP NFjJWW9USU6JRWK=
TGBC11TKB NVy2R49NT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVPqOVdMUUN3ME2yNk4xPDlizszN NWTTem5iW0GQR1XS
BCPAP MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEWyUWpKSzVyPUKyMlYyOSEQvF2= MUjTRW5ITVJ?
HLE NHjRW5ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGDOT4NKSzVyPUKyMlY6PyEQvF2= M4fDfHNCVkeHUh?=
NCI-H727 MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{jBN2lEPTB;MkKuO|M2KM7:TR?= NV61eXg5W0GQR1XS
RD MmruS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUDJR|UxRTJ{Lke1NVgh|ryP NEnEVIRUSU6JRWK=
NCI-H522 NUi4SHdmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYTJR|UxRTJ{Lki0N|Eh|ryP NGLhV5lUSU6JRWK=
CGTH-W-1 NVfVfY5DT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVvJR|UxRTJ|LkC2OFEh|ryP M{TrVnNCVkeHUh?=
SK-LU-1 NUPVcmFJT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIjWO3lKSzVyPUKzMlQ3QDNizszN NUTVN5dFW0GQR1XS
BB65-RCC NIO1eG5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWixTopUUUN3ME2yN{44QDZ|IN88US=> NV7uNFJTW0GQR1XS
HSC-3 NV20dpljT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnnLTWM2OD1{Mz64OVI4KM7:TR?= NXnTSIh7W0GQR1XS
SK-MES-1 MYXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnTJTWM2OD1{ND6wNVYyKM7:TR?= NIPoRotUSU6JRWK=
DB NIfQVG5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWfJR|UxRTJ2LkGwNlgh|ryP MXnTRW5ITVJ?
HO-1-N-1 MlOxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2TzUGlEPTB;MkSuN|A6OyEQvF2= NEjzN3RUSU6JRWK=
MKN1 M{S0Umdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXnJR|UxRTJ2Lk[4JO69VQ>? NHH1ZnNUSU6JRWK=
MN-60 M{TPPWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUHJR|UxRTJ2Lki1NVkh|ryP MkTOV2FPT0WU
8505C NHjqT29Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYDJR|UxRTJ3LkG4OFUh|ryP MkTNV2FPT0WU
COLO-320-HSR NYXYOZlRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnHRTWM2OD1{NT6yNlA5KM7:TR?= NWmxV|lEW0GQR1XS
BB30-HNC M1PWSGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MofDTWM2OD1{NT6yOFg{KM7:TR?= MUfTRW5ITVJ?
KM12 NFTWd2hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEDHUpZKSzVyPUK1MlU5ODdizszN NWDW[WtMW0GQR1XS
NB13 NFu1fFlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVn6O|ZIUUN3ME2yOU42QDl6IN88US=> NFL1enlUSU6JRWK=
HCC2998 NVnLTmJ1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NX3mS2NVUUN3ME2yOk4xOjh|IN88US=> Mk\aV2FPT0WU
U-118-MG NVPtWpA5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXnJR|UxRTJ4LkC4NFgh|ryP NVO2c29jW0GQR1XS
NB10 M{LKcGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1;ET2lEPTB;Mk[uNlM1KM7:TR?= Ml2xV2FPT0WU
SK-LMS-1 MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnfsTWM2OD1{Nz6wO|A1KM7:TR?= MVPTRW5ITVJ?
SW1573 MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYTCUJBYUUN3ME2yO{4yOSEQvF2= NIHveINUSU6JRWK=
LB373-MEL-D MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYXJR|UxRTJ5LkGyPVQh|ryP MVXTRW5ITVJ?
DK-MG MoDTS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUPJR|UxRTJ5LkG4NVch|ryP NWDOVpk6W0GQR1XS
RMG-I MYPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUHJR|UxRTJ5LkKwNlkh|ryP M2jsT3NCVkeHUh?=
SW1088 MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NV\qNIg3UUN3ME2yO{42ODR{IN88US=> MkPmV2FPT0WU
SK-OV-3 NVXvbW84T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYjJR|UxRTJ5Lke1PVMh|ryP NVnzZlBjW0GQR1XS
KP-N-YN M2H6Zmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mm\WTWM2OD1{Nz64NFQ{KM7:TR?= NF3QdnJUSU6JRWK=
RPMI-7951 MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYrJR|UxRTJ6LkK0OVYh|ryP MVXTRW5ITVJ?
CaR-1 M1fl[Wdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXPZ[pVZUUN3ME2yPE42PTh{IN88US=> NWrSXlkxW0GQR1XS
MKN7 M3\nSGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUHJR|UxRTJ6LkW5OlQh|ryP NXH4ZXl3W0GQR1XS
CHP-212 MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVLJR|UxRTJ6Lke0NFEh|ryP Mo\kV2FPT0WU
KYSE-450 NGH4WpVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2nMOWlEPTB;MkiuPFA6OSEQvF2= M4S2fXNCVkeHUh?=
RXF393 M{TreGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUDJR|UxRTJ7LkK5NFYh|ryP NHPwU2lUSU6JRWK=
P30-OHK NFvZZlVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXHJR|UxRTJ7LkOwOFgh|ryP M{eyWnNCVkeHUh?=
Ca9-22 MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFrZXGZKSzVyPUK5MlQzQTlizszN MVPTRW5ITVJ?
RT-112 M1y0Xmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGnNSVRKSzVyPUK5MlQ3OTFizszN MnXMV2FPT0WU
ES1 NFzRUoJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NV3Jb2R3UUN3ME2yPU45PTR2IN88US=> MoC0V2FPT0WU
HCE-4 MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVnMN2g1UUN3ME2yPU45Pzh4IN88US=> NUe5UpJ7W0GQR1XS
AM-38 NHHXWWlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVfJR|UxRTNyLkC2NFYh|ryP Ml\lV2FPT0WU
AsPC-1 Mn;NS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NH;UXoFKSzVyPUOwMlgxPTNizszN M4GyW3NCVkeHUh?=
TE-9 NWLqblM2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXPJR|UxRTNyLki3N|ch|ryP NGPuWXZUSU6JRWK=
HuP-T4 M1TL[2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mn;GTWM2OD1|MD65OlM5KM7:TR?= MmfhV2FPT0WU
LB2518-MEL MV7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXXKbXRTUUN3ME2zNU4xPzR2IN88US=> NXW0TldXW0GQR1XS
NCI-H1703 NGnSVotIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVrtRoJRUUN3ME2zNU4xQTB3IN88US=> NXv2fWY2W0GQR1XS
NCI-H2228 NW\WXHVOT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXnJR|UxRTNzLkS2OVEh|ryP NIfCR|NUSU6JRWK=
SCC-4 MX\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4q0TmlEPTB;M{GuPVE5OSEQvF2= M4HPW3NCVkeHUh?=
KNS-81-FD MkS2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1PIPWlEPTB;M{KuNFEzQCEQvF2= NFPkXWtUSU6JRWK=
NTERA-S-cl-D1 MVTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnyzTWM2OD1|Mj6wO|M6KM7:TR?= NUnaNmJPW0GQR1XS
Daoy NXLqZXAyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVmxSVI2UUN3ME2zNk4xQDN6IN88US=> M4O3bXNCVkeHUh?=
ES4 Mm\tS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NF:5XJBKSzVyPUOyMlM6OjJizszN MkLVV2FPT0WU
MHH-ES-1 NH;GSZRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFXIVY1KSzVyPUOyMlQ5PzJizszN NH;TT4pUSU6JRWK=
C-33-A MoHDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NG\ifldKSzVyPUOyMlc4OjhizszN NITsXpBUSU6JRWK=
BHY MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MX3JR|UxRTN{Lkm0PVUh|ryP M17sdXNCVkeHUh?=
Detroit562 NYn3NZZbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NED5XHJKSzVyPUOzMlY3PTdizszN NUTDeXBHW0GQR1XS
EW-1 M1rI[Gdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGjvcIRKSzVyPUOzMlk{OjJizszN MYnTRW5ITVJ?
NCI-H1395 M1vRfGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{PMUmlEPTB;M{SuNFc6QSEQvF2= MkTVV2FPT0WU
KM-H2 M2ToTmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEXL[FJKSzVyPUO2MlQ4PDNizszN NUTrXXpjW0GQR1XS
NCI-H520 Mk\3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWnJR|UxRTN4Lke1OFEh|ryP NEntbWFUSU6JRWK=
D-392MG MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlTqTWM2OD1|Nz6zN|Q1KM7:TR?= NUmwNndtW0GQR1XS
NOMO-1 MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Ml3oTWM2OD1|Nz64NFg6KM7:TR?= M1;kcnNCVkeHUh?=
TE-6 NXiyN2xET3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4PY[WlEPTB;M{iuNVI1KM7:TR?= M2\wNXNCVkeHUh?=
HT-3 MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Ml7RTWM2OD1|OD60OFM3KM7:TR?= NG[xbYtUSU6JRWK=
RPMI-8226 MlrIS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXO3XZJGUUN3ME2zPE46PTF7IN88US=> NGD3bmNUSU6JRWK=
U251 MYjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Ml;wTWM2OD1|OT6wNVI1KM7:TR?= NYXaPG14W0GQR1XS
GCT NFPuPGFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWnJR|UxRTN7LkG4OVIh|ryP NXOyPGNpW0GQR1XS
A431 NUHDTph4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MojDTWM2OD1|OT6xPFk1KM7:TR?= M{n6NnNCVkeHUh?=
TE-12 M{TUOGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWXOVHI4UUN3ME2zPU4zPDR6IN88US=> NFPhcIpUSU6JRWK=
HMV-II NELGVmtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mn;DTWM2OD1|OT61NFQ4KM7:TR?= NXn4PFV[W0GQR1XS
IST-MES1 Mlj2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmTpTWM2OD12MD6xOVAzKM7:TR?= MUHTRW5ITVJ?
SW13 NFnsU4tIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1zMOmlEPTB;NECuOVE6KM7:TR?= NH3ndIdUSU6JRWK=
SF295 Mmf3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4rMOGlEPTB;NECuPFA3PiEQvF2= NEHzdpNUSU6JRWK=
MDA-MB-157 NVPXNW9IT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3\ETWlEPTB;NECuPVQ3OiEQvF2= Mk\YV2FPT0WU
TE-1 M17zWmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1PnN2lEPTB;NEGuPFcyPCEQvF2= M3\TTnNCVkeHUh?=
HuCCT1 NYrFbY04T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEjWdnZKSzVyPUSyMlUzQDlizszN NUHjSoppW0GQR1XS
KYSE-510 MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3e2dmlEPTB;NEOuNVc2PCEQvF2= NFjWSZVUSU6JRWK=
NCI-H358 NF\zZWtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkLNTWM2OD12ND6wN|A1KM7:TR?= MVnTRW5ITVJ?
SW900 NFf6NJFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmSxTWM2OD12ND6wO|U5KM7:TR?= MX;TRW5ITVJ?
CAS-1 NU\XZoVzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXXuNVgyUUN3ME20OE4xQTlzIN88US=> M37vNXNCVkeHUh?=
TE-8 NITHU5pIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NV;qNnVMUUN3ME20OE42PjV6IN88US=> NXPBc3d5W0GQR1XS
P12-ICHIKAWA NGPvXHRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnHSTWM2OD12ND62NVEzKM7:TR?= M321fHNCVkeHUh?=
YKG-1 MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2rmOGlEPTB;NESuO|gyKM7:TR?= NEnsOXJUSU6JRWK=
SNU-C2B NXvvU5czT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{jFV2lEPTB;NESuO|kxOyEQvF2= NV\YXWxOW0GQR1XS
LCLC-103H MVTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnrXTWM2OD12ND64O|A{KM7:TR?= MnrtV2FPT0WU
U-87-MG MlvjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnHMTWM2OD12NT6xNFIzKM7:TR?= MX;TRW5ITVJ?
HAL-01 MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFrJNHRKSzVyPUS1MlE{PzlizszN MWHTRW5ITVJ?
OVCAR-8 NHrOV3lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIPRV2hKSzVyPUS1MlM2PjRizszN MXHTRW5ITVJ?
KYSE-150 Ml7KS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGftb|BKSzVyPUS3MlExPTJizszN NH\6NpBUSU6JRWK=
OE33 NEHUdVNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4rG[WlEPTB;NEeuNVQzQSEQvF2= NGrjSmhUSU6JRWK=
CAL-62 NXjsRVFOT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHr3eVVKSzVyPUS3MlQxPjhizszN MUTTRW5ITVJ?
TCCSUP M{jBfGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2TSZWlEPTB;NEeuOlI3PCEQvF2= NIDmN3dUSU6JRWK=
H4 NXHWeYlWT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWP6elNbUUN3ME20O{43PjJzIN88US=> MkDSV2FPT0WU
CP66-MEL NXKySZkxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MofaTWM2OD12OD6wO|A1KM7:TR?= MWPTRW5ITVJ?
SNB75 NEj2UpJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkCxTWM2OD12OD6xPFc1KM7:TR?= NHnoS3dUSU6JRWK=
Mo-T NVWxZnlrT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGm2XZNKSzVyPUS4MlI4QSEQvF2= NWfufY93W0GQR1XS
BT-549 NVjvNWEyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXvJR|UxRTR6LkO3Nlkh|ryP MUHTRW5ITVJ?
IGR-1 NILQd2lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXPGeWp2UUN3ME20PE43PjR3IN88US=> MlTIV2FPT0WU
NCI-H1299 Mnf2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoPBTWM2OD12OD63NlQ5KM7:TR?= MlOyV2FPT0WU
ALL-PO MmjOS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MljLTWM2OD12OT65NlY5KM7:TR?= MX;TRW5ITVJ?

... Click to View More Cell Line Experimental Data

In vivo試験 NU7441 intraperitoneally administrated at dose of 10 mg/kg maintains for at least 4 hours shows nontoxic and increases etoposide-induced tumor growth delay 2-fold in mice bearing SW620 xenografts. [2]
臨床試験
特集

プロトコル (参考用のみ)

細胞アッセイ: [2]

細胞株 SW620, LoVo, V3-YAC and V3 cells
濃度 0.5 μM or 1 μM
反応時間 17 hours
実験の流れ The effect of NU7441 on cellular survival following exposure to etoposide, doxorubicin, and ionizing radiation is measured in SW620, LoVo, V3, and V3-YAC cells by clonogenic assays. Briefly, growing cells in six-well plates or 6-cm dishes are exposed to etoposide or doxorubicin with or without NU7441 (0.5 or 1.0 μM) for 16 hours. For radiosensitization studies, NU7441 is added to the cells 1 hour before irradiation. V3 and V3-YAC cells are exposed to γ-irradiation (3.1 Gy/min 137Cesium). SW620 and LoVo are exposed to X-irradiation (2.9 Gy/min at 230 kV, 10 mA) due to the equipment available. After irradiation, the cells are incubated with or without NU7441 for a further 16 hours. Cells are then harvested by trypsinization, counted, and seeded into 10-cm diameter Petri dishes at densities varying from 100 to 105 per dish in drug-free medium for colony formation. Colonies are stained with crystal violet after 10 to 14 days and counted with an automated colony counter. The survival reduction factor (SRF) is calculated as the surviving fraction of cells in the absence of NU7441 divided by the surviving fraction of cells in the presence of NU7441 for any given dose or concentration of cytotoxic agent. The dose modification ratio (DMR90) is calculated as the concentration/dose of cytotoxic agent required to kill 90% of the cells in the absence of NU7441 divided by the concentration/dose of cytotoxic agent required to kill 90% of the cells in the presence of NU7441.

動物実験: [2]

動物モデル Female rude mice bearing SW620 xenografts
製剤 Sterile 0.9% sodium chloride solution
投薬量 10 mg/kg
投与方法 Intraperitoneally administrated

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)

SpeciesMouseRatRabbitGuinea pigHamsterDogMonkeyBaboon
Weight (kg)0.020.151.80.40.0810312
Body Surface Area (m2)0.0070.0250.150.050.020.50.240.6
Km factor361285201220
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Rat dose (mg/kg) = mouse dose (22.4 mg/kg) ×  mouse Km(3)  = 11.2 mg/kg
rat Km(6)
1

参考

化学情報

Download NU7441 (KU-57788) SDF
分子量 413.49
化学式

C25H19NO3S

CAS No. 503468-95-9
保管 2年-20℃
6月-80℃in solvent
別名 N/A
溶解度 (25°C) * In vitro DMSO 3 mg/mL (7.25 mM)
<1 mg/mL (<1 mM)
エタノール <1 mg/mL (<1 mM)
In vivo 4% DMSO+30% PEG 300+5% Tween 80+ddH2O 1mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
化学名 4H-1-Benzopyran-4-one, 8-(4-dibenzothienyl)-2-(4-morpholinyl)-

文献中の引用 (15)

Frequently Asked Questions

  • Question 1
    Previous aliquots were clear and colorless while this time, it becomes yellow when the powder was dissolved in DMSO? Could you advice on this?

    Answer: Slight color variation due to different processing is normal and usually doesn't interfere with the function.

技術サポート&よくある質問(FAQ)

ストックの作り方、阻害剤の保管する方法、細胞実験や動物実験に注意すべきな点を全部含めており、製品を取扱う時よくあった質問に対して取扱説明書でお答えいたします。

電話番号: +1-832-582-8158 Ext:3月曜日〜金曜日 9:00 AM–5:00 PM (米国中部標準時)

他の質問がある場合は、お気軽くお問合せください。

* 必須

Related DNA-PK 阻害剤

  • CHIR-99021 (CT99021)

    CHIR-99021(CT99021)は、GSK-3αとGSK-3β阻害剤で、IC50 がそれぞれ 10 nM と 6.7 nMである。

  • Dorsomorphin

  • MHY1485

    MHY1485 is a potent, and cell-permeable mTOR activator, and also potently inhibits autophagy.

  • Afuresertib (GSK2110183)

    Afuresertib (GSK2110183) is a potent, orally bioavailable Akt inhibitor with Ki of 0.08 nM, 2 nM, and 2.6 nM for Akt1, Akt2, and Akt3, respectively. Phase 2.

  • NU7026

    NU7026 is a potent DNA-PK inhibitor with IC50 of 0.23 μM, 60-fold selective for DNA-PK than PI3K and inactive against both ATM and ATR.

  • KU-0060648

    KU-0060648 is a dual inhibitor of DNA-PK and PI3Kα/β/δ with IC50 of 8.6 nM and 4 nM/0.5 nM/0.1 nM respectively, less inhibition of PI3Kγ with IC50 of 0.59 μM.

  • Rapamycin (Sirolimus)

    Rapamycin (Sirolimus) は、特定のmTOR阻害剤で、IC50 が ~0.1 nMです。

  • MK-2206 2HCl

    MK-2206 2HClは高度選択的に Akt1, Akt2 and Akt3を抑制して、 IC50がそれぞれ 8 nM, 12 nM と 65 nMになる。

    Features:The first allosteric small molecule inhibitor of Akt to enter clinical development.

  • CHIR-99021 (CT99021) HCl

    CHIR-99021 (CT99021) HCl is hydrochloride of CHIR-99021, which is a GSK-3α/β inhibitor with IC50 of 10 nM/6.7 nM; ability to distinguish between GSK-3 and its closest homologs Cdc2 and ERK2.

最近チェックしたアイテム

Tags: NU7441 (KU-57788)を買う | NU7441 (KU-57788)供給者 | NU7441 (KU-57788)を購入する | NU7441 (KU-57788)費用 | NU7441 (KU-57788)生産者 | オーダーNU7441 (KU-57788) | NU7441 (KU-57788)代理店
×
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
お問い合わせ