MG-132 化学構造
分子量: 475.62

高品質保証

文献中の引用(46)

カスタマーフィードバック(9)

Quality Control & MSDS

製品説明

  • Compare Proteasome Inhibitors
    Proteasome製品生物活性の比較
  • 研究分野
  • Combination Therapy
    併用療法

製品の説明

生物活性

製品説明 MG-132は、100nMのIC50によるプロテアソームの強力な阻害剤です。
ターゲット

Proteasome

IC50

100 nM [1]

In vitro試験 MG-132 displays >1000 times more activity than ZLLal in inhibiting the ZLLL-MCA-degrading activity of 20S proteasome with IC50 of 100 nM versus 110 μM. MG-132 also inhibits calpain with IC50 of 1.2 μM. MG-132 induces neurite outgrowth in PC12 cells at an optimal concentration of 20 nM, displaying 500 times more potency than ZLLal. [1] MG-132 (10 μM) potently inhibits TNF-α-induced NF-κB activation, interleukin-8 (IL-8) gene transcription, and IL-8 protein release in A549 cells by inhibition of proteasome-mediated IκBα degradation. [2] MG-132 treatment potently induces p53-dependent apoptosis in KIM-2 cells by 26S proteasome inhibition. [3] Unlike BzLLLCOCHO or PS-341, MG-132 treatment results in weak inhibition of the chymotrypsinlike (CT-L) and peptidylglutamyl peptide hydrolysing (PGPH) activities of the 26S proteasome, whereas multiple myeloma cells (U266 and OPM-2) are more sensitive to induction of apoptosis by MG-132 than BzLLLCOCHO. [4] MG-132 (1 μM) sensitizes TRAIL-resistant prostate cancer cells by activating the AP-1 family members c-Fos and c-Jun, which, in turn, repress the antiapoptotic molecule c-FLIP(L). [5] MG-132 significantly enhances the ability of inositol hexakisphosphate (IP6) to reduce cellular metabolic activity in both PC3 and DU145 androgen-independent prostate cancer (AIPCa) cell lines. [6]
Cell Data
Cell LinesAssay TypeConcentrationIncubation TimeFormulationActivity DescriptionPMID
LPS-stimulated RAW264.7 cells NYDl[mVOTnWwY4Tpc44hSXO|YYm= M2ThOlI2KM7:TR?= MnzOSG1UVw>? NX[zW5hLUW6qaXLpeJMhdmm2cnnjJI95cWSnIIDyc4R2[3Srb36ge4l1cCCLQ{WwJI9nKDBwMTFOwG0> NX7zWGg3OjR4OUe0PVY>
HL-60 NF3l[HZEgXSxdH;4bYMhSXO|YYm= MYe0NEDPxE1? NXy3Wm86PDhiaB?= Mlv3SG1UVw>? MoDiTWM2ODxzMDFOwG0> MVOyOFY6PzR7Nh?=
SMMC-7721 MnfDR5l1d3SxeHnjJGF{e2G7 MWS0NEDPxE1? NFvlTW41QCCq NUHBcXIzTE2VTx?= NGPzc4ZKSzVyPUeuNUDPxE1? MYGyOFY6PzR7Nh?=
A-549 NUf1OmVPS3m2b4TvfIlkKEG|c3H5 MXW0NEDPxE1? M2\icFQ5KGh? MVTEUXNQ MWDJR|UxRDFyIN88US=> Mmr2NlQ3QTd2OU[=
MCF-7 NWHzNWo6S3m2b4TvfIlkKEG|c3H5 NIiyZXI1OCEQvF2= NIH3dpA1QCCq NEXEeoxFVVOR MmPhTWM2OD15LkOg{txO Mk\mNlQ3QTd2OU[=
SW-480 MlzsR5l1d3SxeHnjJGF{e2G7 MnzBOFAh|ryP MYS0PEBp NIKxfZVFVVOR NHfMWG9KSzVyPUSg{txO NFnlW2szPDZ7N{S5Oi=>
NCI-H929 NH\UXWpEgXSxdH;4bYMhSXO|YYm= MYWxJO69VQ>? NGrJUms4OiCq MYfEUXNQ MYnJR|UxRTBwMUeg{txO Ml;4NlQ3OjVyOEi=
293T MmDDR5l1d3SxeHnjJGF{e2G7 M2PMS|ExKM7:TR?= NFz4ZZg4OiCq NH;SZmNFVVOR Mmj1TWM2ODx{IN88US=> MlrVNlQ3OjVyOEi=
293T MofESpVv[3Srb36gRZN{[Xl? MX:xNEDPxE1? M4TGN|I1KGh? M37pR2ROW09? NWTNfJZ1VW:mZYLheIVtgSCrbnT1Z4V{KGinYYStd4hw[2tiIB?= M3XZWlI1PjJ3MEi4
HeLa MlP3T4lv[XOnIFHzd4F6 MkC2NVAh|ryP M371Z|EhcA>? M4jPOWROW09? MmK2TY5lfWOnczDQRXJRKGOuZXH2ZYdmKGK7IHnubIljcXSrbnegdJJwe2Wjc3;t[UBi[3Srdnn0fS=> NWK0U5hSOjR|MkG4N|M>
MDA-MB-231 MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXixJO69VQ>? MWC3NkBp M2DjUmROW09? MUTJR|UxRTBwMUig{txO NFLBSYczPDF3M{KwOi=>
MCF-7 MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1LrXVEh|ryP M17NOVczKGh? NGPDUllFVVOR MlvITWM2OD1yLkGzJO69VQ>? M{PJPFI1OTV|MkC2
MCF10A MnPFS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFrQcW0yKM7:TR?= NUTJVmJ3PzJiaB?= NYHJW|VjTE2VTx?= MVHJR|UxRTBwMkmg{txO MXKyOFE2OzJyNh?=
HEK-293 NIG0OHpMcW6jc3WgRZN{[Xl? NXvS[WNwOiCjbnSgNlAh|ryP NUKwS5NnOiCq M{nHZ2ROW09? Mon3TY5pcWKrdIOgR4hVNUxiYXP0bZZqfHlid3n0bEBKSzVyIH;mJFkhdk1i M3;oO|I{PTRyN{mw
Calu6 MoThSpVv[3Srb36gRZN{[Xl? NHPkZXgyOCEQvF2= MnjKNVghcA>? MkLlSG1UVw>? MXPTbYdvcW[rY3HueIx6KGGlY4XteYxifGW|IH\yZZRigGmwIIDy[YN2enOxch?= MWqyN|UxPjR6Nh?=
IFN-gamma-induced RAW264.7 NGjMRm1HfW6ldHnvckBCe3OjeR?= NWna[4RDTE2VTx?= M1PyTWlvcGmkaYTzJI5qfHKrYzDvfIll\SCycn;keYN1cW:wIIfpeIghUUN3MDDv[kAxNjB5NzFOwG0> Mmi3NlIzPzd{N{e=
IPC227F NITBVldEgXSxdH;4bYMhSXO|YYm= NWjDe4dYOSEQvF2= NUHae4FSPDhiaB?= MnfISG1UVw>? NIrqdnpKSzVyPUCuNFc4KM7:TR?= NY\CVHllOjF7MkS1Nlg>
Hepa-1c1c7 MWHGeY5kfGmxbjDBd5NigQ>? NF\LSXczPSEQvF2= NYixfJY6PiCq Mor1SG1UVw>? M2HvO2lv[3KnYYPld{BPemZ{IIDyc5RmcW5ibHX2[Yw> NXzRVYFMOjB|OUK1OFQ>
COS-7 MlvWR5l1d3SxeHnjJGF{e2G7 MXmxNEDPxE1? NGXWTFhFVVOR NH;qbZhKSzVyPEGwJO69VQ>? NEjTXIgyQDB6OEC5Oy=>
HuH-7 NXv1RmR1S3m2b4TvfIlkKEG|c3H5 MkP2NVAh|ryP MWfEUXNQ NX\RV3RUUUN3MEyxNEDPxE1? NGD6OIgyQDB6OEC5Oy=>
OCI-Ly3 NYjGelZxTnWwY4Tpc44hSXO|YYm= NGfQdXkyOCEQvF5CpC=> Mn\WOEBp M4rrbmROW09? NW\MZWFHUW6mdXPld{BpfW2jbjDJb4FxeGGEYXzwbIEhe3SjYnnsbZpifGmxbjD3bZRpKEWFNUCgc4YhOSEQvF2= NX;DZmZnOThyMkSxNVM>
A2780 cDDP M3fxfWFxd3C2b4Ppd{BCe3OjeR?= MUSyOEBp M3K1bWROW09? NG[0cpNKdmS3Y3XzJIFxd3C2b4Ppd{BjgSCrbnjpZol1cW6pIGDUSW4h\GWpcnHkZZRqd25? NFzVTVEyPzZ6NECxPC=>
LPS-stimulated RAW264.7 cells NYjvR416TnWwY4Tpc44hSXO|YYm= M3\4PWROW09? NVThXmw1UW6qaXLpeJMhVkZva3HwdIFDKESQQTDibY5lcW6p Mn\ENVc1ODd{N{e=
PC12 NHniXXVHfW6ldHnvckBCe3OjeR?= NXfneHdNOTByIN88UeKh MWWyOEBp M2[zNmROW09? M3PBRmlvcGmkaYTzJFYuV0iGQT2gZY5lKEh{T{KtbY5lfWOnZDDjfZRwfG:6aXPpeJk> NV\5WZpEOTdzNUi0OVQ>
PC3 NX64UWZ3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2P2SFIxKM7:TR?= MnXYOFghcA>? M{nvd2ROW09? NFLZVFNKSzVyPUCuOkDPxE1? M{T4S|E3Pjh4NUO3
LP-1 NWH0dFB4SXCxcITvd4l{KEG|c3H5 Mn3mN|AxKG6P MVGyOEBp NW\xeZl4TE2VTx?= NUnxTWt1UW6mdXPld{BieG:ydH;zbZMh[nliaX7jdoVie2mwZzDjcIVifmWmIGDBVnAhdGW4ZXygZY5lKHKnZIXjbY5oKE2lbD2xJJBzd3SnaX6gcIV3\Wx? MkXkNVU6PTh3OEm=
ES6 NX[yVWQ2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4X1dWlEPTB;MD6wNVMxPiEQvF2= M3n0PXNCVkeHUh?=
A101D Mme1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnXCTWM2OD1yLkCzNlc6KM7:TR?= NYf6Uo03W0GQR1XS
OCUB-M NXPhcJl1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWj6fmJtUUN3ME2wMlA{PzN5IN88US=> NFftWVhUSU6JRWK=
LB2518-MEL MXTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVW1OI1sUUN3ME2wMlA{PzZizszN MnPSV2FPT0WU
SH-4 NF\0W|lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYDMNlFLUUN3ME2wMlA1OzFizszN NGTPV2JUSU6JRWK=
KNS-42 M4LEUmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3\vbGlEPTB;MD6wOFQ1OSEQvF2= MnXMV2FPT0WU
DSH1 M3W2V2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3rPU2lEPTB;MD6wOVI5QSEQvF2= M2\NUnNCVkeHUh?=
NTERA-S-cl-D1 MlztS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGXrXFRKSzVyPUCuNFU4PzJizszN NIS2[YJUSU6JRWK=
D-542MG MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NITVc45KSzVyPUCuNFU6PTdizszN MlLvV2FPT0WU
KS-1 NI\j[JlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3vwN2lEPTB;MD6wOlQ2QCEQvF2= MVnTRW5ITVJ?
BL-41 M{jPd2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHLpXIFKSzVyPUCuNFY6PDdizszN MVLTRW5ITVJ?
LXF-289 NX3wb2pzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoHnTWM2OD1yLkC3NFY3KM7:TR?= M2K3eXNCVkeHUh?=
D-247MG NHnFXXhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2X2cGlEPTB;MD6wO|IxQSEQvF2= Mni4V2FPT0WU
MMAC-SF NVLvWmlrT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIjBOoxKSzVyPUCuNFczPjhizszN NEL0SpNUSU6JRWK=
CP66-MEL M1HhZ2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUXs[HVUUUN3ME2wMlA4PSEQvF2= MlH3V2FPT0WU
LB771-HNC NFzONIZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHLtdYxKSzVyPUCuNFgxOzZizszN MY\TRW5ITVJ?
no-10 NGPTXW1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1TvcGlEPTB;MD6wPFkxQSEQvF2= NX6y[ngxW0GQR1XS
A388 MXzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkTRTWM2OD1yLkC5NFY2KM7:TR?= MmrqV2FPT0WU
OPM-2 MYPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVPuZoFSUUN3ME2wMlExPDd2IN88US=> M1H4bnNCVkeHUh?=
OVCAR-4 NGn6bGVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFHDTZVKSzVyPUCuNVA6OzhizszN NILYZYFUSU6JRWK=
HOP-62 M1THN2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWm0c|ZuUUN3ME2wMlExQTR7IN88US=> NV3vdnBEW0GQR1XS
ML-2 M1zWcGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIexeVlKSzVyPUCuNVE5ODZizszN NWfOOWZ2W0GQR1XS
UACC-257 NH3EW3JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYO0UHY1UUN3ME2wMlEyQTJ5IN88US=> NWfuXHhzW0GQR1XS
NEC8 MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M13Bc2lEPTB;MD6xNVk6PSEQvF2= MknVV2FPT0WU
ONS-76 MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{fieGlEPTB;MD6xNlk{PSEQvF2= M4jKPHNCVkeHUh?=
KE-37 M2Pmd2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2DxNmlEPTB;MD6xN|I4QCEQvF2= NFXNW5pUSU6JRWK=
HT-144 M{nDNGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnmwTWM2OD1yLkGzPFk2KM7:TR?= NIqwNppUSU6JRWK=
LB2241-RCC NHWzOYxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXfJR|UxRTBwMUSyOFch|ryP M1LV[XNCVkeHUh?=
TE-5 MX7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmXTTWM2OD1yLkG0Nlc5KM7:TR?= M1rrbHNCVkeHUh?=
KINGS-1 MmPUS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4DJVGlEPTB;MD6xOFc6KM7:TR?= M4TEO3NCVkeHUh?=
NCI-H69 NFvY[4NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGDqW5pKSzVyPUCuNVUyPDFizszN NX;E[ItMW0GQR1XS
CAS-1 NX;EXWtuT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NY\vT4FjUUN3ME2wMlE2PDh{IN88US=> NGLD[lZUSU6JRWK=
D-263MG NXLmfpE{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MU\JR|UxRTBwMU[wNFYh|ryP MXrTRW5ITVJ?
A253 MUjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2j0RWlEPTB;MD6xOlEzQCEQvF2= NE\yUlZUSU6JRWK=
PF-382 MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NF:xbVVKSzVyPUCuNVY4ODZizszN M4DacXNCVkeHUh?=
CESS NUe5NnVJT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4L1e2lEPTB;MD6xO|A3KM7:TR?= M363PHNCVkeHUh?=
MZ2-MEL M1P6dGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mk\jTWM2OD1yLkG3OVU6KM7:TR?= M{PJR3NCVkeHUh?=
HEL M4Ltfmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUnNUIR4UUN3ME2wMlE5PTF5IN88US=> M3jibnNCVkeHUh?=
D-392MG M2PnXmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NV;nSJRxUUN3ME2wMlE6OTF3IN88US=> NX3Z[YRuW0GQR1XS
SK-LMS-1 NIj4ZlhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVrJR|UxRTBwMUmzNFMh|ryP MVjTRW5ITVJ?
GI-ME-N MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVvJR|UxRTBwMUmzNFYh|ryP MnLnV2FPT0WU
LB831-BLC MVTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIHsNmNKSzVyPUCuNVk{PCEQvF2= MUfTRW5ITVJ?
DU-4475 NFjjd4hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3TIN2lEPTB;MD6xPVY2QCEQvF2= Mn\qV2FPT0WU
IST-SL1 MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Ml;YTWM2OD1yLkKwNFk1KM7:TR?= NUmwTG5xW0GQR1XS
GAK MXTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2XtPGlEPTB;MD6yNFU{PCEQvF2= Mn;LV2FPT0WU
EW-1 NYPjOVR4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NV3pPWhbUUN3ME2wMlIyODR5IN88US=> MVTTRW5ITVJ?
LAMA-84 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4\pOmlEPTB;MD6yNVg2OSEQvF2= M4XWcHNCVkeHUh?=
SK-UT-1 M4n6XGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mly2TWM2OD1yLkKyNFQ6KM7:TR?= NVvNcnpoW0GQR1XS
VA-ES-BJ NEnxNIhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4XNcGlEPTB;MD6yNlI2PyEQvF2= MYHTRW5ITVJ?
ACN NYHUe2J[T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MX3JR|UxRTBwMkK2N|gh|ryP NX7CdoJMW0GQR1XS
SK-PN-DW NUTxNFYzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlzjTWM2OD1yLkKzNVkh|ryP M2XYVHNCVkeHUh?=
HD-MY-Z MlHGS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXrERWxpUUN3ME2wMlI{OzB|IN88US=> NWf3dnVDW0GQR1XS
LB373-MEL-D M3rQUmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoG5TWM2OD1yLkK0NVk5KM7:TR?= MoXEV2FPT0WU
COLO-829 M17heWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M13VT2lEPTB;MD6yOFI2PyEQvF2= MW\TRW5ITVJ?
ES8 MmXpS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4TSSWlEPTB;MD6yOFc3OyEQvF2= M{P2RnNCVkeHUh?=
RXF393 M{S3OWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Ml\NTWM2OD1yLkK1NFE2KM7:TR?= NW\QUplKW0GQR1XS
TK10 MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFLLVGZKSzVyPUCuNlU1OzVizszN MlfpV2FPT0WU
LOUCY NH7ydWJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3TFOmlEPTB;MD6yOVQ2PiEQvF2= M3TRXXNCVkeHUh?=
MZ7-mel MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M33CT2lEPTB;MD6yOlM4PCEQvF2= MVzTRW5ITVJ?
CP67-MEL Ml3IS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEXsO2ZKSzVyPUCuNlY4OyEQvF2= M4P0VnNCVkeHUh?=
C2BBe1 NVO0OpVMT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYrJR|UxRTBwMke5NFch|ryP M3\aenNCVkeHUh?=
K052 NHKxO|dIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmO5TWM2OD1yLkK4PVkh|ryP MXvTRW5ITVJ?
MOLT-16 M{jhSWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mk\xTWM2OD1yLkK5OVI1KM7:TR?= NHjOV3VUSU6JRWK=
KNS-81-FD MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MULJR|UxRTBwM{CzNlMh|ryP NFnjbVNUSU6JRWK=
CMK M4jBNWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHTQRZVKSzVyPUCuN|EyOiEQvF2= MYPTRW5ITVJ?
LAN-6 NHvBdYpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnP0TWM2OD1yLkOxN{DPxE1? MoH6V2FPT0WU
KLE M3;ESmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWfDOXhnUUN3ME2wMlMyOzB4IN88US=> M{jX[XNCVkeHUh?=
NCCIT M1jKR2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NY\LfVhZUUN3ME2wMlMyPzh|IN88US=> MYrTRW5ITVJ?
HH MkPUS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGC3[2pKSzVyPUCuN|I5QTdizszN M1rlN3NCVkeHUh?=
TE-8 M{[xV2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIjEcHpKSzVyPUCuN|QzPzlizszN M2L6SHNCVkeHUh?=
GDM-1 Ml7KS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mm\TTWM2OD1yLkO1NVA1KM7:TR?= MmP3V2FPT0WU
NCI-H747 M3nFOmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3jEUWlEPTB;MD6zO|ExOyEQvF2= MX\TRW5ITVJ?
NCI-H1092 NEO5dXZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MU\JR|UxRTBwM{i4OFQh|ryP MXHTRW5ITVJ?
8-MG-BA MoXoS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWTIO4l3UUN3ME2wMlM6QDN5IN88US=> NFrYZ2FUSU6JRWK=
NB17 M3nvdWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEjRSo1KSzVyPUCuOFI6PyEQvF2= MVXTRW5ITVJ?
LC4-1 M2r4OGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmP5TWM2OD1yLkSzOlA4KM7:TR?= M{PGfXNCVkeHUh?=
TE-1 M4\wN2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEG3NGtKSzVyPUCuOFUyOTlizszN M{O5VnNCVkeHUh?=
KALS-1 M2P0OWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVLUV5I2UUN3ME2wMlQ3PTh2IN88US=> MVHTRW5ITVJ?
CCRF-CEM M2r4TGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mn7VTWM2OD1yLkS3Olc1KM7:TR?= MYPTRW5ITVJ?
OS-RC-2 NF\XeHJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWjYenFRUUN3ME2wMlQ4QTd{IN88US=> NYizeWV3W0GQR1XS
A704 NIrSPXJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3XK[mlEPTB;MD60PFY6OiEQvF2= NYnBeXZIW0GQR1XS
BB49-HNC NHfrNWlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEPycXhKSzVyPUCuOFkxQTZizszN MXjTRW5ITVJ?
EVSA-T MnHTS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIjQS2tKSzVyPUCuOFk6OTFizszN NGL6PIhUSU6JRWK=
Mo-T NWPmfolST3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHTGVI1KSzVyPUCuOVE4PjJizszN Ml;hV2FPT0WU
MONO-MAC-6 MoXRS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{jwSmlEPTB;MD61N|YyOSEQvF2= NXjwSHoxW0GQR1XS
BB65-RCC MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NV7TWIl2UUN3ME2wMlU3QDFzIN88US=> NILzS4pUSU6JRWK=
NCI-H1882 Mnj5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlfLTWM2OD1yLkW5NFM3KM7:TR?= MUnTRW5ITVJ?
TE-9 NVTxfIRqT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmmwTWM2OD1yLk[xNFM{KM7:TR?= NHHrfmxUSU6JRWK=
NCI-H2126 M33MTWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVm4SZplUUN3ME2wMlYzPjZ7IN88US=> NYDReop2W0GQR1XS
SF268 NYTiUpc6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Ml;oTWM2OD1yLk[1OlQyKM7:TR?= NH;1WHZUSU6JRWK=
SW872 MlS3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFHVNXZKSzVyPUCuOlU4OjlizszN NF[3d2lUSU6JRWK=
LS-513 NWfGPGZHT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3u5[2lEPTB;MD62Olc2OSEQvF2= MnLVV2FPT0WU
NCI-H1355 NE\jTVNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2nOcGlEPTB;MD62PFYyQSEQvF2= MkTYV2FPT0WU
BL-70 MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1PaVGlEPTB;MD62PVM5QCEQvF2= M3W1d3NCVkeHUh?=
NCI-SNU-5 MV7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mn7XTWM2OD1yLk[5OVQ2KM7:TR?= NGOwV2hUSU6JRWK=
SNU-C2B M4P1bmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGG4UmZKSzVyPUCuO|A4OzlizszN M2jKR3NCVkeHUh?=
GB-1 NFvPPZBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVLJR|UxRTBwN{KxNlQh|ryP M37mSXNCVkeHUh?=
CTB-1 MmTFS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUfaZmM5UUN3ME2wMlc4QTV3IN88US=> MWHTRW5ITVJ?
Becker NYP0W3RNT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MV7JR|UxRTBwN{m2NlEh|ryP MVTTRW5ITVJ?
KM12 NH7MWXhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2LESWlEPTB;MD64OVQ3PiEQvF2= MmHJV2FPT0WU
ES7 MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVPoZZR5UUN3ME2wMlg6PjVizszN NIrVO4tUSU6JRWK=
COLO-684 NYLhdmlHT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MljGTWM2OD1yLkmwOlU5KM7:TR?= NWXjUWtHW0GQR1XS
HCC2998 M3q5RWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoL3TWM2OD1yLkmzPFU1KM7:TR?= MYLTRW5ITVJ?
TE-10 Ml7wS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUnJR|UxRTBwOU[0N{DPxE1? MW\TRW5ITVJ?
SF126 MnW2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoG2TWM2OD1yLkm4PVcyKM7:TR?= M2D0S3NCVkeHUh?=
EKVX M1;KNGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NF:0cI9KSzVyPUGuNFM1PDJizszN NUPrW3E2W0GQR1XS
KARPAS-45 MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1vXUmlEPTB;MT6wOFAyPiEQvF2= Mm\YV2FPT0WU
KGN NFL2dGFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYPjfIp[UUN3ME2xMlA2ODR3IN88US=> NVzGfJduW0GQR1XS
ES1 MmHYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXO0OI9tUUN3ME2xMlA4QTJzIN88US=> MYDTRW5ITVJ?
L-540 NX:5[pN[T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3PIbmlEPTB;MT6xNVg{QSEQvF2= Mk\hV2FPT0WU
KURAMOCHI M{nobWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGXudZlKSzVyPUGuNVI{PzRizszN M1XFSHNCVkeHUh?=
LU-65 MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUPJR|UxRTFwMUK3OVMh|ryP MXnTRW5ITVJ?
MFH-ino Mk[yS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2LmXmlEPTB;MT6xO|UxOSEQvF2= NWfZOWlzW0GQR1XS
NCI-H23 M{DW[2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NG\l[oxKSzVyPUGuNlA1OSEQvF2= NVf4dmI3W0GQR1XS
IA-LM NWTmeGFQT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NF71UmpKSzVyPUGuNlQyOTZizszN M2HHfHNCVkeHUh?=
PSN1 NF;XV3JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYLJR|UxRTFwMkewNVYh|ryP Mn61V2FPT0WU
NCI-H719 M1TnWWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NV\PcYt{UUN3ME2xMlI4PDFzIN88US=> NYDhRVh5W0GQR1XS
SW684 NFzEZnlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGroVVNKSzVyPUGuNlg3PTlizszN M2LjU3NCVkeHUh?=
HCE-4 MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MonlTWM2OD1zLkOwNlIyKM7:TR?= M2PYO3NCVkeHUh?=
EW-16 NWS5elcxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkHITWM2OD1zLkOxN|Q4KM7:TR?= NXX5PGY5W0GQR1XS
NCI-H128 NWPheWZIT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NES5[|ZKSzVyPUGuN|U5OTRizszN NVf3VIdIW0GQR1XS
HC-1 NIKwd|lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIPHb3VKSzVyPUGuN|gyPyEQvF2= NUfK[pVQW0GQR1XS
IST-MES1 NWnPUY9ZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkL1TWM2OD1zLkSwNlA5KM7:TR?= MWXTRW5ITVJ?
Raji NED0eFdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NV3UNWNjUUN3ME2xMlQyQDVizszN MWXTRW5ITVJ?
DMS-114 M3L0Vmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVTJR|UxRTFwNES1N|kh|ryP Mo\2V2FPT0WU
GI-1 NIDJcHhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXTJR|UxRTFwNEexN|Eh|ryP M2TLfXNCVkeHUh?=
NCI-H2081 MmraS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmfITWM2OD1zLkW1NVk3KM7:TR?= MoPFV2FPT0WU
LC-1F M2jGOmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFTjdmxKSzVyPUGuOVUyQThizszN M{\HcnNCVkeHUh?=
NCI-H2227 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkOyTWM2OD1zLk[xOVYyKM7:TR?= MWnTRW5ITVJ?
D-502MG NYTmfoN2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3jqbGlEPTB;MT62O|IyOSEQvF2= NYi5VFEzW0GQR1XS
NCI-H2141 MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYT4bXpvUUN3ME2xMlY4OzF5IN88US=> M1;QVXNCVkeHUh?=
LS-411N NGjEfFZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{TI[WlEPTB;MT62PVgxPyEQvF2= Mmq0V2FPT0WU
SU-DHL-1 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVSxO5lrUUN3ME2xMlcyOjhzIN88US=> NFn5SZpUSU6JRWK=
BB30-HNC MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{K5TmlEPTB;MT63NlY5PSEQvF2= NXSxWI5uW0GQR1XS
TE-15 NW\HVHZTT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{\EOWlEPTB;MT65NlM4OyEQvF2= M13aPXNCVkeHUh?=
JVM-3 NGL3UmhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFe4d5NKSzVyPUGuPVM6ODRizszN M2W5dHNCVkeHUh?=
IST-SL2 NEPzOVJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1\COGlEPTB;Mj6wNVI2OiEQvF2= MWTTRW5ITVJ?
EW-18 Mlz2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mo\STWM2OD1{LkCyN|M4KM7:TR?= MYTTRW5ITVJ?
DJM-1 NIn1OmhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4nmT2lEPTB;Mj6wNlU2OiEQvF2= NFviZYlUSU6JRWK=
no-11 M1HBcmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3rTb2lEPTB;Mj6wN|ExPCEQvF2= NEC0e2dUSU6JRWK=
QIMR-WIL NELo[ldIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoDKTWM2OD1{LkG2O|YzKM7:TR?= NIT5W21USU6JRWK=
MC-CAR M1Owfmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3;5dWlEPTB;Mj6yNlk2KM7:TR?= NGfNXIhUSU6JRWK=
KM-H2 NYTCWHRHT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{K1UGlEPTB;Mj6yPVA1OyEQvF2= M1vsb3NCVkeHUh?=
ECC12 NIX4OGdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXHJR|UxRTJwM{e5OEDPxE1? NXftZoxkW0GQR1XS
HCE-T NVfhPY5yT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHnGWG1KSzVyPUKuOFQ5QDNizszN NVvt[IhiW0GQR1XS
MFM-223 MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MofGTWM2OD1{LkWwPFcyKM7:TR?= MmTCV2FPT0WU
SW982 NXfXcHZNT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlS2TWM2OD1{LkWxOFgh|ryP M1T5fHNCVkeHUh?=
KG-1 MlHUS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mk\BTWM2OD1{Lki4O|kyKM7:TR?= NEjOcndUSU6JRWK=
ES4 NYP0TYFpT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYn4R3JzUUN3ME2zMlA3OTFzIN88US=> NEXKTlhUSU6JRWK=
SCC-3 MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mnf2TWM2OD1|LkGwPFQ5KM7:TR?= M4rYbXNCVkeHUh?=
RH-1 NH3SZ|RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MV7JR|UxRTNwM{i3OFgh|ryP NVnkU3hPW0GQR1XS
NCI-H748 M37NcGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MULJR|UxRTNwNESyOlYh|ryP NXvjcW9uW0GQR1XS
HCC2218 NWPxPVJuT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4jMZ2lEPTB;Mz60Olk{PyEQvF2= M2f2WHNCVkeHUh?=
MEG-01 M1LtSWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoDCTWM2OD1|LkW5Olgh|ryP NEf4VoJUSU6JRWK=
NB12 NXPHWpQzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkHRTWM2OD1|LkW5PFg5KM7:TR?= MWDTRW5ITVJ?
SNB75 MWHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWKxRoNIUUN3ME2zMlYxOTB|IN88US=> MWPTRW5ITVJ?
KMS-12-PE MYXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWDJR|UxRTNwNke3NlMh|ryP MonpV2FPT0WU
SKM-1 M12wWmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWOyTI5DUUN3ME2zMlcyOzd4IN88US=> NV24Vnh4W0GQR1XS
COLO-320-HSR NFfEV2lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFzVWpdKSzVyPUOuO|U3OzRizszN NXLSb|BZW0GQR1XS
NKM-1 NXHyPGNYT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGLjOIhKSzVyPUOuO|c{PzhizszN M1P3UXNCVkeHUh?=
TE-6 MmrDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFjjPHdKSzVyPUOuPVQ2PjFizszN NXHE[pI2W0GQR1XS
D-336MG Mo\4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIjJSmRKSzVyPUSuNFEyPjZizszN NHmxOnRUSU6JRWK=
NCI-H1650 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NH;5UZBKSzVyPUSuNVU4QTdizszN MUDTRW5ITVJ?
ES3 MmTWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4ezbGlEPTB;ND6zNlgzPCEQvF2= MWjTRW5ITVJ?
YT NH\UT4FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4Dpb2lEPTB;ND6zOVQzPCEQvF2= M{PIVnNCVkeHUh?=
ES5 M330cWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{jKNmlEPTB;ND60NFI2PSEQvF2= NX7UVZAzW0GQR1XS
LB647-SCLC NWDZU4g4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Ml;WTWM2OD12LkW2N|A5KM7:TR?= NVXSZYhlW0GQR1XS
HAL-01 NYHPTWt4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlfNTWM2OD12LkW3NFM1KM7:TR?= NXftT|dmW0GQR1XS
LP-1 MoXLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2nROmlEPTB;ND63NlM4OSEQvF2= MmTIV2FPT0WU
BC-1 NWnyW3V2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2XBdGlEPTB;NT6wNFQ1PyEQvF2= MY\TRW5ITVJ?
EB-3 MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkT5TWM2OD13LkCzNFQyKM7:TR?= NELKRolUSU6JRWK=
GT3TKB MoPZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVjJR|UxRTVwMUe2OlIh|ryP M37OeXNCVkeHUh?=
NCI-H209 NF;4T5ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHLF[FJKSzVyPUWuNVk{PTJizszN Mn3kV2FPT0WU
BT-474 NY\nU4dVT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmH2TWM2OD13LkKzNVAzKM7:TR?= MWHTRW5ITVJ?
RKO M2f2Z2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmjyTWM2OD13LkKzOFIzKM7:TR?= MVTTRW5ITVJ?
SIMA MoLlS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWHJR|UxRTVwM{C3OlUh|ryP NXqweHhPW0GQR1XS
RL MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGrWSVJKSzVyPUWuN|c2PDFizszN MUXTRW5ITVJ?
GCIY M1Px[2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1u4RmlEPTB;NT60O|I{PiEQvF2= NWjuZnVNW0GQR1XS
Calu-6 NHr5SGtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVXnUHJOUUN3ME21MlYzOiEQvF2= M3vCe3NCVkeHUh?=
ALL-PO NVzpPHprT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFzNXJFKSzVyPUWuOlM4QTVizszN MUTTRW5ITVJ?
ARH-77 MnHUS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHnsc|RKSzVyPUWuOlcxQDdizszN MXfTRW5ITVJ?
A4-Fuk NUXlXmpRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEHCe4JKSzVyPU[uNFgyOThizszN M1\WV3NCVkeHUh?=
NCI-H1581 NFjhUphIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NY\qbVh5UUN3ME22MlI{QDR7IN88US=> NUK0[5JUW0GQR1XS
HUTU-80 MoL6S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M33Hb2lEPTB;Nj6zOlg6PyEQvF2= NX;lRXI3W0GQR1XS
TGW M4HvU2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MX\JR|UxRTZwNEW1PVMh|ryP NFLvNHZUSU6JRWK=
SK-N-FI MmnsS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWPJR|UxRTZwNEW4OVQh|ryP MYPTRW5ITVJ?
U-266 MkPwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2nR[2lEPTB;Nj61NVkzPiEQvF2= NFy0WnBUSU6JRWK=
EM-2 MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3XG[GlEPTB;Nj62O|A6QSEQvF2= NFjTWI9USU6JRWK=
NMC-G1 M2LrTGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXXJR|UxRTZwN{G4PVUh|ryP MUfTRW5ITVJ?
KASUMI-1 NHuzWGNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MU\JR|UxRTZwOES3PFch|ryP M4HVOHNCVkeHUh?=
NALM-6 NVr3fmlZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXztV2E2UUN3ME22Mlg3PzV2IN88US=> MWPTRW5ITVJ?
OCI-AML2 MnvmS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn;KTWM2OD15LkCwN|I3KM7:TR?= MlPIV2FPT0WU
SHP-77 M{LiVGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NX7xeVN1UUN3ME23MlIzPDNizszN NVPZV3c3W0GQR1XS
NOMO-1 M4HOTWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHvHSXZKSzVyPUeuNlQzPTRizszN NG\rflRUSU6JRWK=
SK-N-DZ M4XqVGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MV;JR|UxRTdwN{GwPFkh|ryP MmLFV2FPT0WU
LB1047-RCC MUDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFnLeWZKSzVyPUeuO|IzOzFizszN NU\sTnRCW0GQR1XS
MZ1-PC NHHqN5BIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1niPGlEPTB;Nz64OlU2QCEQvF2= MYHTRW5ITVJ?
NB10 NITwV2RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXfJR|UxRTdwOUm1OVYh|ryP M1jUVnNCVkeHUh?=
RL95-2 NGHH[2JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWnJR|UxRThwMUC4OFIh|ryP MkjCV2FPT0WU
OMC-1 M3HSd2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmTXTWM2OD16LkWyNVkyKM7:TR?= NWPnVFdWW0GQR1XS
D-283MED NWi5eGNvT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYnJR|UxRThwOUG3NVkh|ryP NUjUR5NlW0GQR1XS
MC116 MmS2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXiwNYFmUUN3ME24Mlk4QTRizszN MoH4V2FPT0WU
SJSA-1 M2fEVWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIHTVo1KSzVyPUmuNFkxQTFizszN NHy1S5BUSU6JRWK=
JiyoyeP-2003 NVKzelVVT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4rRTWlEPTB;OT6yPVMyPyEQvF2= NVzqWY5TW0GQR1XS
IST-MEL1 M2jqUWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXPZe5gzUUN3ME25Mlc1OTl6IN88US=> MYLTRW5ITVJ?
CTV-1 MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1\MfWlEPTB;MUCuNFk4QSEQvF2= NVK5UmFXW0GQR1XS
NH-12 MlTjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGHSWnBKSzVyPUGwMlI1OzNizszN Ml7nV2FPT0WU
CA46 NFLVWoNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1;LOGlEPTB;MUCuN|YyKM7:TR?= NEPZb4dUSU6JRWK=
NCI-SNU-1 NXLMelZPT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{nFOmlEPTB;MUCuOFk3QSEQvF2= MULTRW5ITVJ?
SCLC-21H M{WzNmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M17lSGlEPTB;MUCuOlU6PiEQvF2= MmnDV2FPT0WU
EC-GI-10 MUDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWTJR|UxRTFyLkewN|Eh|ryP M2\DXHNCVkeHUh?=
SR Mn\1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3PlPWlEPTB;MUGuNFE5PSEQvF2= MnX1V2FPT0WU
NCI-H1648 MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3naO2lEPTB;MUGuNFk3PSEQvF2= NGHVUFNUSU6JRWK=
TGBC1TKB MnzuS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2nMR2lEPTB;MUGuOFExOiEQvF2= MU\TRW5ITVJ?
EW-11 MmPkS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFjqb2tKSzVyPUGxMlUyQDZizszN NVjyXm0yW0GQR1XS
SK-MM-2 NWHUO|RZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmT2TWM2OD1zMT64NFYyKM7:TR?= NXLwflRzW0GQR1XS
NCI-H524 NUPZdnFqT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NU\K[GVYUUN3ME2xNU46QDJ{IN88US=> NVLJV|FpW0GQR1XS
NOS-1 NV:4WpRmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{GxdmlEPTB;MUKuNFM1PSEQvF2= MUjTRW5ITVJ?
AM-38 NH24SZpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2XtPWlEPTB;MUKuOVY{OyEQvF2= NFXjR|ZUSU6JRWK=
A498 M{Szdmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NH7OSYdKSzVyPUGyMlcxPjlizszN MXvTRW5ITVJ?
KARPAS-422 MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXvJR|UxRTF{Lke0PVYh|ryP M{XNU3NCVkeHUh?=
LU-139 NULPSWJDT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFTM[YlKSzVyPUGyMlkxOjZizszN Ml33V2FPT0WU
COR-L88 MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NF3me4pKSzVyPUGyMlk{QDJizszN NELjbnFUSU6JRWK=
K5 M{nSeWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIjSS4RKSzVyPUGyMlk1PjJizszN NGDhZXlUSU6JRWK=
NB13 M4DUeGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVzyNFFlUUN3ME2xNk46Pzh|IN88US=> NVnST3M4W0GQR1XS
MRK-nu-1 MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVfSfIxmUUN3ME2xN{4yQTVizszN MX\TRW5ITVJ?
MHH-NB-11 M1zuNmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlT2TWM2OD1zMz6yPVAzKM7:TR?= M1Sxc3NCVkeHUh?=
KU812 Mk[xS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFzhSXhKSzVyPUGzMlYyOjRizszN MnrvV2FPT0WU
TE-12 M2LDe2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MU\JR|UxRTF|Lk[5PVQh|ryP NX;CV2pnW0GQR1XS
NCI-N87 NHXENY5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MX\JR|UxRTF|LkezOkDPxE1? MmLNV2FPT0WU
EB2 MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2GyfWlEPTB;MUOuPFUxPSEQvF2= MVXTRW5ITVJ?
DB M2\meGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYfaS5QzUUN3ME2xN{46QDh3IN88US=> MWTTRW5ITVJ?
697 Mnz2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGrvXFNKSzVyPUG0MlQ2OTFizszN MnLMV2FPT0WU
MSTO-211H MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYPhOlh4UUN3ME2xOE44PDR6IN88US=> MknNV2FPT0WU
JVM-2 NGS2[ZNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXHJR|UxRTF2Lke3N|Uh|ryP NYPK[oxRW0GQR1XS
COLO-824 MnjhS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVH5cHdTUUN3ME2xOE44QTl2IN88US=> M3HPZ3NCVkeHUh?=
BC-3 MWHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoTrTWM2OD1zNT6zPVgh|ryP M3f5NHNCVkeHUh?=
BOKU NWfCNHN[T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NInG[JNKSzVyPUG1Mlk3ODhizszN NEfNOWhUSU6JRWK=
GOTO NGiwOZlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVzDRYN3UUN3ME2xOk46PjF5IN88US=> MmS1V2FPT0WU
HCC2157 MVTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHnJOZFKSzVyPUG3MlQ4PTVizszN MUHTRW5ITVJ?
LS-1034 NWrHTZU5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUXQd2ZHUUN3ME2xO{43QDF6IN88US=> NHXjTINUSU6JRWK=
CAL-148 NFvKbnRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4TGV2lEPTB;MUeuPVc6PiEQvF2= MVrTRW5ITVJ?
MOLT-4 M4jZTmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYfJR|UxRTF6LkiyNFgh|ryP MWfTRW5ITVJ?
Daudi MUHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYLFN3psUUN3ME2xPE46OjNzIN88US=> MkLIV2FPT0WU
J-RT3-T3-5 M3H1bGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXvJR|UxRTF7LkSwOlYh|ryP M1PwSHNCVkeHUh?=
KMOE-2 M1r4eWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEWw[ZlKSzVyPUG5MlY1QDJizszN MonKV2FPT0WU
HL-60 NV7JN21XT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Ml\yTWM2OD1{MD6xPVY2KM7:TR?= M4rV[nNCVkeHUh?=
P31-FUJ NW\ZfohwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MX3JR|UxRTJyLkS3OVMh|ryP NF3XcpBUSU6JRWK=
IM-9 NX62XmxxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXfJR|UxRTJyLk[yNlQh|ryP MkCyV2FPT0WU
HDLM-2 MknFS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MV\JR|UxRTJyLki4NlEh|ryP Mon1V2FPT0WU
NCI-H1304 M3TFRWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFvLfFlKSzVyPUKxMlA{OTFizszN NV3IVHJqW0GQR1XS
NCI-H345 MV7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3TMNWlEPTB;MkGuNFY1OyEQvF2= NF:4OGFUSU6JRWK=
RPMI-6666 M3z1TWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXHYRpVTUUN3ME2yNU4{PjB{IN88US=> M17uXXNCVkeHUh?=
GR-ST MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEixU|dKSzVyPUKxMlQyPyEQvF2= MVLTRW5ITVJ?
CHP-126 MoG3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWPKSFQ3UUN3ME2yNU43OThzIN88US=> MVTTRW5ITVJ?
EHEB NVLLO2UzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVLJR|UxRTJzLk[3N|Eh|ryP MX;TRW5ITVJ?
CPC-N MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmjnTWM2OD1{ND6wNlAyKM7:TR?= MVfTRW5ITVJ?
NB1 NIfXZXNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVjKe|ZVUUN3ME2yOE43QTN7IN88US=> M{[2U3NCVkeHUh?=
LS-123 MVfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MULJR|UxRTJ2LkmwNVIh|ryP NYjLVpBvW0GQR1XS
ST486 NXP3VlNZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MU\JR|UxRTJ3LkGxNVMh|ryP M4PRVHNCVkeHUh?=
NCI-H1963 NWrVVGhqT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mn24TWM2OD1{Nj6wOlI{KM7:TR?= NI\tV4FUSU6JRWK=
U-87-MG MmjHS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYHLWYd4UUN3ME2yOk44PjR2IN88US=> MoXzV2FPT0WU
COR-L279 NW\uXYx[T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWnLdppTUUN3ME2yOk44QTJ{IN88US=> M4[5SHNCVkeHUh?=
LU-165 M1[wfWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXW4Z5V{UUN3ME2yPE4xQDZzIN88US=> MorHV2FPT0WU
COLO-800 M4HqfWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmrETWM2OD1{OD6yPVU3KM7:TR?= M4LBW3NCVkeHUh?=
ETK-1 NGLMdVNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXrjeJhFUUN3ME2yPE4{PDR4IN88US=> NEnXbnFUSU6JRWK=
LNCaP-Clone-FGC MYXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHzadXlKSzVyPUK5MlkzQDFizszN MnPuV2FPT0WU
SIG-M5 MmnHS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVf2SYc2UUN3ME2zNE44QTV{IN88US=> MmrqV2FPT0WU
NB6 MnTwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVXJR|UxRTNyLkm1NFMh|ryP M3HMenNCVkeHUh?=
NCI-H2107 NUTSV|NNT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Ml\wTWM2OD1|MT6yN|M5KM7:TR?= M{XSdnNCVkeHUh?=
SNU-C1 NX\IU2x4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVvmZ4tDUUN3ME2zNU4{OTJ4IN88US=> M2juSXNCVkeHUh?=
JAR MmDiS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVrJR|UxRTNzLkO3PVkh|ryP NUfQeFB6W0GQR1XS
L-363 MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWjJR|UxRTN{LkKxOFQh|ryP Mnz6V2FPT0WU
EW-24 MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3PveWlEPTB;M{KuN|Q4PCEQvF2= NW\5co1UW0GQR1XS
NB69 NH\GU5NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWTqeHR7UUN3ME2zN{43PDV2IN88US=> Mm\lV2FPT0WU
EW-13 NIOzU2xIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3rLNWlEPTB;M{OuPFk3QSEQvF2= MVLTRW5ITVJ?
Ramos-2G6-4C10 NFPqbFdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVfJR|UxRTN2LkK5PVMh|ryP NEDjT4pUSU6JRWK=
TE-11 MlznS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVjJR|UxRTN2LkS4NlIh|ryP MlPBV2FPT0WU
L-428 NYXBUIhNT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3LNfWlEPTB;M{SuO|U{PiEQvF2= NUm0UWl5W0GQR1XS
KP-N-YN MnzzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXXJR|UxRTN2LkmwOVch|ryP M1vsR3NCVkeHUh?=
CGTH-W-1 NX7iSGl3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHj1R4dKSzVyPUO2MlkxPDhizszN M4jBUXNCVkeHUh?=
K-562 MVfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkTkTWM2OD1|Nz6wPFY1KM7:TR?= MXzTRW5ITVJ?
NCI-H1299 MlrVS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWTJR|UxRTN6LkG2NFMh|ryP NXvTcIlnW0GQR1XS
RCC10RGB M1HpOWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXTJR|UxRTN6LkKwPFMh|ryP MXPTRW5ITVJ?
NCI-SNU-16 MVfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGGxfYtKSzVyPUO4MlU3PTNizszN NUHS[oRDW0GQR1XS
LC-2-ad NYDoWXgzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYnJR|UxRTN7LkSzN|ch|ryP M2fGZnNCVkeHUh?=
MHH-PREB-1 NIXsWFNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVGxcnJrUUN3ME2zPU44Ozh6IN88US=> NVv1dnFUW0GQR1XS
NCI-H64 MmD3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEmxN41KSzVyPUSwMlA6PDhizszN NVLrbWIyW0GQR1XS
LB996-RCC NWnyOZVWT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Ml3STWM2OD12MD64O|E3KM7:TR?= M2i0[HNCVkeHUh?=
DEL NFjQcW1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYHaNYUzUUN3ME20NU41PDB3IN88US=> NYjtUolvW0GQR1XS
MLMA M2j3b2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVfJR|UxRTRzLke1PVUh|ryP NYjV[WlZW0GQR1XS
SBC-1 NGKyc21Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYLJR|UxRTR{LkG4NFYh|ryP NIrXXZhUSU6JRWK=
MPP-89 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXfJR|UxRTR{LkW4O|Uh|ryP NFXzNYxUSU6JRWK=
MV-4-11 MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmS3TWM2OD12Mj65NFY4KM7:TR?= NUL5SJVsW0GQR1XS
EoL-1- NXXUeW1wT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mn;jTWM2OD12ND6xOVY5KM7:TR?= M3HMNHNCVkeHUh?=
CW-2 M{P5Vmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnrETWM2OD12ND64N|QzKM7:TR?= NIe5WIVUSU6JRWK=
HT NES3R|lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3\ucGlEPTB;NEWuO|AxPyEQvF2= MmTPV2FPT0WU
SW954 MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mn;pTWM2OD12Nz60NVI5KM7:TR?= MXHTRW5ITVJ?
A3-KAW MkXQS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MX\JR|UxRTR7LkiwOlEh|ryP NUOxVWVLW0GQR1XS
TC-YIK NFmyS25Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXrJR|UxRTVyLkCzOlMh|ryP NFvBOolUSU6JRWK=
SW962 MmKxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3\UdmlEPTB;NUSuPFM2PyEQvF2= MlPXV2FPT0WU
KP-N-RT-BM-1 MlX6S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYrqUHh4UUN3ME21Ok43PjN6IN88US=> MVfTRW5ITVJ?
NCI-H1395 MnLmS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUTJR|UxRTV6LkixO|Ih|ryP MkK0V2FPT0WU
RPMI-8402 MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M33iR2lEPTB;NUiuPVUzPiEQvF2= NEPiVpJUSU6JRWK=
SCH NEH0Xo5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoHjTWM2OD14MD65OlM5KM7:TR?= NXvJR2k{W0GQR1XS
NCI-H2196 NFXQTnZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3O2RWlEPTB;NkGuNlMyKM7:TR?= MoO1V2FPT0WU
LOXIMVI MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mn3NTWM2OD14MT64NlY3KM7:TR?= MoO4V2FPT0WU
TGBC24TKB NEnPT3ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWnrPI0yUUN3ME22Nk4yPDlzIN88US=> NWm5WmdOW0GQR1XS
SK-MEL-2 MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVTQXHU5UUN3ME22N{46QDl{IN88US=> NYDIVo54W0GQR1XS
U-698-M NIXaRnBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXe5SZBvUUN3ME22PE42Pjh5IN88US=> Mn3yV2FPT0WU
NCI-H1522 NHr1NY9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1nocmlEPTB;NkmuNFA1PyEQvF2= MVfTRW5ITVJ?
UACC-812 MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXfEW5B5UUN3ME22PU42OjB7IN88US=> NITrS29USU6JRWK=
MHH-CALL-2 M1\kdGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGjEXmZKSzVyPUewMlA3KM7:TR?= NVfRSmt1W0GQR1XS
NB5 NYLSV4VUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWj0PW9NUUN3ME23NE4{PDZ6IN88US=> MoTIV2FPT0WU
KARPAS-299 NUX2blhLT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGnTRpRKSzVyPUewMlQ1PDdizszN MVjTRW5ITVJ?
NCI-H1694 Mm[yS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEf5XYRKSzVyPUexMlA{OiEQvF2= M2ft[HNCVkeHUh?=
NCI-H82 M1O0bmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4O4TGlEPTB;N{GuPVUxPyEQvF2= M1f4WXNCVkeHUh?=
SCC-15 MnnGS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NV;T[HJ1UUN3ME23Nk4{PCEQvF2= M{ftcHNCVkeHUh?=
NCI-H1436 Mk\wS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkLSTWM2OD15Mj63OFU3KM7:TR?= NE\UeYVUSU6JRWK=
ATN-1 MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{WxTWlEPTB;N{SuOVA2KM7:TR?= MVvTRW5ITVJ?
RPMI-8866 MlLNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEfjepBKSzVyPUe0Mlc2ODlizszN NIPQRmdUSU6JRWK=
HCC1599 NH;aNlFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnHVTWM2OD15ND64O|MzKM7:TR?= MX\TRW5ITVJ?
NCI-H1155 M3\wTWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkPZTWM2OD15ND65N|Y4KM7:TR?= MXrTRW5ITVJ?
DOHH-2 NF\wTnBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWjSXmYzUUN3ME23OE46PTF2IN88US=> MUDTRW5ITVJ?
SK-NEP-1 NXHi[HJ[T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVXJR|UxRTd3LkC3OVQh|ryP M3HGSHNCVkeHUh?=
HCC1187 M2K3WWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIfV[2pKSzVyPUe3MlYyOjJizszN MlX6V2FPT0WU
NCI-H322M MnfWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1qzb2lEPTB;N{iuN|cxQSEQvF2= MV;TRW5ITVJ?
NCI-H526 MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXzJR|UxRTd6LkW4O|ch|ryP M2Ht[3NCVkeHUh?=
NCI-H2171 M3y3Z2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3PxSGlEPTB;N{muOFE{PiEQvF2= Mnm3V2FPT0WU
COLO-668 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIXOXmpKSzVyPUixMlU5QDRizszN NUPq[oE4W0GQR1XS
RS4-11 NHLPc|dIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3jicGlEPTB;OEKuNlUxPSEQvF2= NIrhb4FUSU6JRWK=
NCI-H716 M1nPeWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFPuOm5KSzVyPUiyMlkxPzVizszN NFvKcVJUSU6JRWK=
LU-134-A MmXsS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmDwTWM2OD16Mz6xN|UyKM7:TR?= NFnXZllUSU6JRWK=
RPMI-8226 MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXTJR|UxRTh2LkKxNFch|ryP NWnQeJllW0GQR1XS
KY821 NYXEO2tuT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NULMdHJ2UUN3ME25NU43PTVzIN88US=> MlnPV2FPT0WU
ECC4 MoSzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NX\x[mJ4UUN3ME25N{45OjZ7IN88US=> NYPnU3pDW0GQR1XS
EW-3 Ml\CS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1\qO2lEPTB;OUSuPVA5OSEQvF2= NYnwb|A1W0GQR1XS
NB7 Mn6wS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIHBbFZKSzVyPUm1Mlc4QDZizszN NHjER5NUSU6JRWK=
NCI-H720 NUHlZpIyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHXXb5pKSzVyPUm4MlQxPjFizszN NXfETXlKW0GQR1XS
NCI-H446 NIL2UZJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXrJR|UxRTl7Lke1PFgh|ryP MXzTRW5ITVJ?
NCI-H889 NFLLenVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVPtbIU6UUN3ME2xNFQvOjR{IN88US=> NF;GPZNUSU6JRWK=
EW-22 NXnySVNUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVnqdIRUUUN3ME2xNFYvOTlizszN NG[x[2NUSU6JRWK=
BV-173 NXfPNZhbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkH1TWM2OD1zMEiuO|I5KM7:TR?= M1K2[HNCVkeHUh?=
WSU-NHL MkK1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWny[WJkUUN3ME2xNFkvPjdzIN88US=> M2LN[nNCVkeHUh?=
MN-60 MkDGS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MX7JR|UxRTFyOT62PUDPxE1? MnzxV2FPT0WU
DG-75 M2ixZmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYDUNo5lUUN3ME2xNVMvOzV{IN88US=> M4nHcHNCVkeHUh?=
DMS-79 NIXEXGZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIfoVnBKSzVyPUGxO{4{QDJizszN NHXKfHFUSU6JRWK=
SK-MEL-1 MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVnJR|UxRTFzOD6wNFkh|ryP NHvaRYdUSU6JRWK=
DMS-153 M4PBTGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXXJR|UxRTF{MT63OFUh|ryP NFXJUYFUSU6JRWK=
NCI-H510A Mo[1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUjEfFdmUUN3ME2xNlcvOzJizszN MVfTRW5ITVJ?
BE-13 MVTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlH2TWM2OD1zM{SuNFQ1KM7:TR?= NIXS[oxUSU6JRWK=
KP-N-YS NVzUNZBiT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NY[5cZQzUUN3ME2xN|kvPzN4IN88US=> MUDTRW5ITVJ?
SUP-T1 Ml\JS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGTxXllKSzVyPUG0N{44ODhizszN NVfyeoZrW0GQR1XS
EW-12 MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NULvc3BSUUN3ME2xOFQvPjl7IN88US=> Mn\5V2FPT0WU
NB14 NF3wfHBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmnVTWM2OD1zNEeuNFgzKM7:TR?= MkDvV2FPT0WU
MDA-MB-134-VI NVjTbFlwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4S4fmlEPTB;MUS4MlI3QCEQvF2= NUTsUVltW0GQR1XS
NCI-H1770 MkflS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1Xne2lEPTB;MUW2MlI4QSEQvF2= M4q1NnNCVkeHUh?=
TUR NEjtUG5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4[3WmlEPTB;MU[3Mlg4KM7:TR?= MmT6V2FPT0WU
NCI-H1417 MoTuS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHqz[3RKSzVyPUG4NE4{OzFizszN NEnxVXZUSU6JRWK=
IMR-5 NVWwSmwyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MX3JR|UxRTF6MT61O|Eh|ryP NUS3WoFlW0GQR1XS
NCI-H226 NYO5[pI6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEPHSZlKSzVyPUG4PE45PjZizszN NV3jVGxYW0GQR1XS
NCI-H187 M4fVUWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEK0RXJKSzVyPUG5NE4xPjRizszN NFfPXnRUSU6JRWK=
SF539 M2Dp[Gdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYTJR|UxRTF7Mj63Nlgh|ryP NVLVe3diW0GQR1XS
TALL-1 NEXifnVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoHvTWM2OD1zOUiuN|A1KM7:TR?= M1nwUnNCVkeHUh?=
TE-441-T NUTBbmhTT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoTvTWM2OD1zOUmuO|M6KM7:TR?= NEPFWJBUSU6JRWK=
REH NWXMbZUxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWrJR|UxRTJ|Nj62NlYh|ryP MoXkV2FPT0WU
MS-1 MmnkS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWTJR|UxRTJ|OT6xNlEh|ryP M{jycHNCVkeHUh?=
THP-1 NYjDW45mT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NU\P[XFsUUN3ME2yOlQvPzN6IN88US=> MkjoV2FPT0WU
NCI-H1838 MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHHBNmxKSzVyPUK3NU41PTZizszN MnTjV2FPT0WU
P30-OHK NX:0b5VnT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGrHNm1KSzVyPUK4N{45PDdizszN M2\jcnNCVkeHUh?=
C8166 NHK5[pVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIDn[nhKSzVyPUO0OU4{OzhizszN NH[1VW9USU6JRWK=

... Click to View More Cell Line Experimental Data

In vivo試験 Administration of MG-132 effectively rescues the expression levels and plasma membrane localization of dystrophin, β-dystroglycan, α-bdystroglycan, and α-sarcoglycan in skeletal muscle fibers from mdx mice, reduces muscle membrane damage, and ameliorates the histopathological signs of muscular dystrophy. [7] MG-132 treatment significantly reduces immobilization-induced skeletal muscle atrophy in mice, by downregulating the muscle-specific ubiquitin ligases atrogin-1/MAFbx and MuRF-1 mRNA. [8]
臨床試験
特集

プロトコル (参考用のみ)

キナーゼアッセイ:

[1]

Measurement of inhibitory activities of MG-132 against 20S proteasome The reaction mixture for the 20S proteasome inhibitory assay contains 0.1 M Tris-acetate, pH 7.0, 20S proteasome, MG-132, and 25 μM substrate dissolved in dimethyl sulfoxide in a final volume of 1 mL. After incuba tion at 37 °C for 15 minutes, the reaction is stopped by the addition of 0.1 mL of 10% SDS and 0.9 mL of 0.1M Tris acetate, pH 9.0. The fluorescence of the reaction products is measured. To determine the IC50 against 20S proteasome, various concentrations of MG-132 are included in the assay mixture.

細胞アッセイ:

[3]

細胞株 KIM-2, HC11, and ES
濃度 Dissolved in DMSO, final concentrations ~25 μM
反応時間 24, and 48 hours
実験の流れ

Cells are exposed to various concentrations of MG-132 for 24, and 48 hours. Supernatant and monolayer cells are harvested by centrifugation and fixed in 70% ethanol in PBS for staining with acridine orange. Equal volumes of cells and acridine orange (5 mg/mL in PBS) are mixed on a microscope slide and examined by fluorescence microscopy. For annexin V analysis, cells are harvested by centrifugation and stained with annexin V and propidium iodide. For cell cycle analysis, cells are rehydrated in PBS at room temperature for 10 minutes, followed by staining with propidium iodide (5 mg/mL). All samples are analyzed using a Coulter Epics XL flow cytometer.

動物実験:

[7]

動物モデル Male mdx (C57BL/10ScSn DMD mdx) mice
製剤 Dissolved in DMSO, and diluted in PBS
投薬量 ~10 μg/kg/day
投与方法 Injection

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)

SpeciesMouseRatRabbitGuinea pigHamsterDogMonkeyBaboon
Weight (kg)0.020.151.80.40.0810312
Body Surface Area (m2)0.0070.0250.150.050.020.50.240.6
Km factor361285201220
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Rat dose (mg/kg) = mouse dose (22.4 mg/kg) ×  mouse Km(3)  = 11.2 mg/kg
rat Km(6)
1

参考

化学情報

Download MG-132 SDF
分子量 475.62
化学式

C26H41N3O5

CAS No. 133407-82-6
保管 3年-20℃
2年-80℃in solvent
別名 N/A
溶解度 (25°C) * In vitro DMSO 95 mg/mL (199.73 mM)
Ethanol 95 mg/mL (199.73 mM)
Water <1 mg/mL
In vivo 4% DMSO+30% PEG 300+20% propylene glycol+ddH2O 2mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
化学名 benzyl (S)-4-methyl-1-((S)-4-methyl-1-((S)-4-methyl-1-oxopentan-2-ylamino)-1-oxopentan-2-ylamino)-1-oxopentan-2-ylcarbamate

文献中の引用 (46)

Frequently Asked Questions

  • Question 1
    I want to know whether it contains EDTA or other chelating agent in this product(S2619)?

    Answer: Our S2619 MG-132 doesn't contain EDTA or other chelating agent.

技術サポート&よくある質問(FAQ)

ストックの作り方、阻害剤の保管する方法、細胞実験や動物実験に注意すべきな点を全部含めており、製品を取扱う時よくあった質問に対して取扱説明書でお答えいたします。

電話番号: +1-832-582-8158 Ext:3月曜日〜金曜日 9:00 AM–5:00 PM (米国中部標準時)

他の質問がある場合は、お気軽くお問合せください。

* 必須

Related プロテアソーム 阻害剤

  • VR23

    VR23は1種の有効なプロテアソーム阻害剤で、トリプシン様プロテアソーム(trypsin-like proteasomes)、キモトリプシン様プロテアソーム(chymotrypsin-like proteasomes)とカスパーゼ様プロテアソーム(caspase-like proteasomes)に作用するIC50値は1 nM、50-100 nMと 3 μMそれぞれに分かれます。

  • Calpeptin

    Calpeptinは1種の有効的で、細胞浸透性のカルパイン( calpain)阻害剤で、カルパインI(豚赤血球)、カルパインII (豚腎臓)、パパイン(Papain)とカルパインI(人血小板)に対するID50値は52 nM、34 nM、138 nMと40 nMそれぞれに分かれます。

  • Marimastat (BB-2516)

    Marimastat (BB-2516)は1種の広範囲に使用されるマトリックスメタロプロテアーゼ(MMP)阻害剤で、MMP-9、MMP-1、MMP-2、MMP-14とMMP-7に作用する IC50値は3 nM、5 nM、6 nM、9 nMと13 nMそれぞれに分かれます。臨床3期。

  • Ledipasvir (GS5885)

    Ledipasvir(GS5885)は1種のHCV NS5Aポリメラーゼ(polymerase)阻害剤で、C型肝炎ウイルス感染の治療に使用します。

  • Bortezomib (PS-341)

    Bortezomib (PS-341)は、強力なプロテアソーム阻害剤で、Kiが0.6nMです。

  • Carfilzomib (PR-171)

    Carfilzomib (PR-171) is a proteasome inhibitor with IC50 less than 5 nM.

  • Ixazomib (MLN2238)

    Ixazomib (MLN2238)は窒素端加帽の二ペプチドロイシンホウ酸で、20Sプロテアソームのカイモトリプシン類(β5)加水分解部位を抑制、IC50が3.4nM、Ki値が0.93nM。

    Features:A first-in-class proteasome inhibitor that has improved pharmacokinetics (PK), pharmacodynamics(PD), and antitumor activity in preclinical studies.

  • ONX-0914 (PR-957)

    ONX-0914(PR-957)は、恒常的プロテアソームのための最小限の交差反応性を持つ強力かつ選択的な免疫プロテアソームの阻害剤です。

    Features:The first highly selective, small molecule inhibitor of the immunoproteasome. Potential use in cancer and autoimmune diseases (e.g. rheumatoid arthritis, inflammatory bowel disease, and lupus).

  • MLN9708

    MLN9708は二代目経口生物の有効性にプロテアソーム選択阻害剤で、20Sプロテアソームのカイモトリプシン類(β5)加水分解部位に作用すると、IC50が3.4nM、Ki値が0.93nMになる。

    Features:The 1st oral proteasome inhibitor in early stage clinical trials for Multiple Myeloma.

最近チェックしたアイテム

Tags: MG-132を買う | MG-132供給者 | MG-132を購入する | MG-132費用 | MG-132生産者 | オーダーMG-132 | MG-132代理店
×
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
お問い合わせ