17-AAG (Tanespimycin) 化学構造
分子量: 585.69

高品質保証

カスタマーフィードバック(7)

MSDS

製品説明

  • Compare HSP (e.g. HSP90) Inhibitors
    HSP (e.g. HSP90)製品生物活性の比較
  • 研究分野

製品の説明

生物活性

製品説明 17-AAG (Tanespimycin)は、5nMのIC50による強力な熱ショックタンパク質90(Hsp90)阻害剤です。
ターゲット HSP90
IC50 5 nM [1]
In vitro試験 17-AAG, an analog of geldanamycin, exhibits greater than 100 times higher binding affinity for Hsp90 derived from HER-2-overexpressing cancer cells (BT474, N87, SKOV3 and SKBR3) or BT474 breast carcinoma cells with IC50 values of 5-6 nM. [1] 17-AAG causes the degradation of HER2, HER3, Akt, and both mutant and wild-type androgen receptor (AR), leading to the RB-dependent G1 growth arrest of prostate cancer cells such as LNCaP, LAPC-4, DU-145, and PC-3 with IC50 values of 25-45 nM. [2] In addition to inducing apoptosis of Ba/F3 cells transformed with wild-type BCR-ABL with an IC50 of 5.2 μM, 17-AAG has the ability to induce apoptosis of cells transformed with imatinib mesylate-resistant T315I and E255K BCR-ABL mutants with IC50 values of 2.3 μM and 1.0 μM, respectively, by inducing the degradation of both wild-type BCR-ABL protein and mutants. [3]
Cell Data
Cell LinesAssay TypeConcentrationIncubation TimeFormulationActivity DescriptionPMID
A549 M1vObmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mm\HTWM2OD1yLkCwNFMxOyEQvF2= MlnlV2FPT0WU
IST-MEL1 M4rKcGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWnJR|UxRTBwMECwOFA4KM7:TR?= NInmWWFUSU6JRWK=
NCI-SNU-1 MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGi1fJdKSzVyPUCuNFAzODdizszN M2LnXnNCVkeHUh?=
FADU MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEjaVpVKSzVyPUCuNFAzODlizszN Mm[0V2FPT0WU
C32 NXXBd4hrT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1qyUWlEPTB;MD6wNFMxPCEQvF2= MlLsV2FPT0WU
D-566MG Ml\GS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWrJR|UxRTBwMECzPUDPxE1? M4D3XXNCVkeHUh?=
LXF-289 MorVS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NX;MbYJHUUN3ME2wMlAxPDF7IN88US=> M2jtZnNCVkeHUh?=
HGC-27 MnvNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkPqTWM2OD1yLkCwOVEh|ryP NEHuenRUSU6JRWK=
RPMI-7951 M136cGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUfiR5M2UUN3ME2wMlAxPzF5IN88US=> MXzTRW5ITVJ?
HSC-3 NXyzcYFwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHnwbVdKSzVyPUCuNFA6OjlizszN NEi3UJZUSU6JRWK=
MIA-PaCa-2 MWDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmC4TWM2OD1yLkCxNFA6KM7:TR?= NEDxSWZUSU6JRWK=
KS-1 MoTvS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3LrXGlEPTB;MD6wNVM2PSEQvF2= NYHVb41uW0GQR1XS
CAL-51 NFi1VHlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2G2[WlEPTB;MD6wNVQxPSEQvF2= NW\wfFN{W0GQR1XS
MDA-MB-361 MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWXJR|UxRTBwMEG0PVUh|ryP MkDkV2FPT0WU
TI-73 NF32TXVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnXzTWM2OD1yLkCxO|k3KM7:TR?= NHzLcIJUSU6JRWK=
AGS M{\3RWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MorlTWM2OD1yLkCxPVM5KM7:TR?= MUTTRW5ITVJ?
NCI-H460 NUX5V4d6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1vEWmlEPTB;MD6wNVk4PCEQvF2= NV60XnFpW0GQR1XS
A204 MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHHhTVVKSzVyPUCuNFIzPDlizszN MlnkV2FPT0WU
CHL-1 MojMS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVjGNZA1UUN3ME2wMlAzOjVzIN88US=> NXWwPZFDW0GQR1XS
DU-4475 MVTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkL1TWM2OD1yLkCyNlYyKM7:TR?= MXjTRW5ITVJ?
CGTH-W-1 MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGPxfFNKSzVyPUCuNFI{PDlizszN M2H3bXNCVkeHUh?=
HCC2218 MmPsS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHHBVIFKSzVyPUCuNFI1QTRizszN M1rHO3NCVkeHUh?=
A2780 NF32Z2VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MljJTWM2OD1yLkCyOVMyKM7:TR?= MonJV2FPT0WU
NCI-H720 Mof3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUDMUlJEUUN3ME2wMlAzPTR4IN88US=> NWK5RYw6W0GQR1XS
NCI-N87 M{Ts[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkjXTWM2OD1yLkCyOVk{KM7:TR?= NIPmS|dUSU6JRWK=
CHP-212 NVW2SXFRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{jae2lEPTB;MD6wNlYzQCEQvF2= NH3LZWpUSU6JRWK=
NCI-H23 NIGwfJdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4fxOGlEPTB;MD6wNlY3PSEQvF2= MYrTRW5ITVJ?
D-263MG Ml;OS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MV\JR|UxRTBwMEK3PFYh|ryP Mk\0V2FPT0WU
ME-180 NIXLT2tIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2CwfWlEPTB;MD6wNlg6OSEQvF2= MnzPV2FPT0WU
SW982 NH3rXlJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFTtO2RKSzVyPUCuNFI6QTlizszN NEjMPItUSU6JRWK=
OE19 NEj1OGRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlrxTWM2OD1yLkCzNFc4KM7:TR?= M2qxSnNCVkeHUh?=
SK-LU-1 NHrGPZpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1riTGlEPTB;MD6wN|A5OiEQvF2= M1zhWHNCVkeHUh?=
H4 MnzaS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MX\JR|UxRTBwMEOwPUDPxE1? NVLHbXBkW0GQR1XS
HT-144 Mlu4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn;QTWM2OD1yLkCzNFk{KM7:TR?= NFTIcFdUSU6JRWK=
SK-UT-1 M{XW[Gdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIm4bVNKSzVyPUCuNFMyPzhizszN M1LHS3NCVkeHUh?=
D-336MG NGX6PYxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NH;DeW5KSzVyPUCuNFM{ODlizszN NF3nNpVUSU6JRWK=
MDA-MB-175-VII NFPaZmpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWH6O|loUUN3ME2wMlA{OzV2IN88US=> NUnye49VW0GQR1XS
GAMG MmTjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXLJR|UxRTBwMEO0N|Uh|ryP MXLTRW5ITVJ?
CP50-MEL-B NICyXIpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmTETWM2OD1yLkCzOFUh|ryP NEm5OVhUSU6JRWK=
OVCAR-5 MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYrJR|UxRTBwMEO0PEDPxE1? NXX6eIk6W0GQR1XS
SK-MES-1 NUe1NHVWT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFm2bYFKSzVyPUCuNFM3ODZizszN MnfRV2FPT0WU
VM-CUB-1 M3f0T2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3;HPGlEPTB;MD6wN|Y2PyEQvF2= NIfOcI5USU6JRWK=
WM-115 Ml\GS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHS4WYlKSzVyPUCuNFM4PjJizszN NFLwV5lUSU6JRWK=
DSH1 NXrzT492T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVXJR|UxRTBwMEO4NFch|ryP M1\XXHNCVkeHUh?=
Becker MlO1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MX3JR|UxRTBwMEO4PFUh|ryP M3LlNXNCVkeHUh?=
SW962 NGnrW|RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mo\QTWM2OD1yLkCzPVQ2KM7:TR?= NYXJVpljW0GQR1XS
TYK-nu NH7TOWdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlHXTWM2OD1yLkCzPVg2KM7:TR?= MoDnV2FPT0WU
HO-1-N-1 NH\XbmtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mnn3TWM2OD1yLkC0NFIyKM7:TR?= M3PzV3NCVkeHUh?=
T98G M1vkSmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlzGTWM2OD1yLkC0NVA{KM7:TR?= NVS3dm5VW0GQR1XS
ACN M2rrfGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mo\kTWM2OD1yLkC0NVYzKM7:TR?= MkXnV2FPT0WU
SW780 NX75RWJJT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGjTWnRKSzVyPUCuNFQzODNizszN NUnKN|k1W0GQR1XS
Detroit562 MYXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFjkeHFKSzVyPUCuNFQzOzlizszN M4XzSXNCVkeHUh?=
BB49-HNC NVnKS3pmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUn3d4JuUUN3ME2wMlA1OjR|IN88US=> M1XEXnNCVkeHUh?=
HN M1zTV2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MX3JR|UxRTBwMESyO|Ih|ryP MYjTRW5ITVJ?
H9 M1jYW2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEXJW|lKSzVyPUCuNFQ{PzFizszN NV73flFSW0GQR1XS
VA-ES-BJ NYPZTYpLT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlXaTWM2OD1yLkC0OFQ4KM7:TR?= M{H6N3NCVkeHUh?=
MEL-JUSO NFX5TJlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3;xc2lEPTB;MD6wOFQ4PSEQvF2= MYHTRW5ITVJ?
BT-474 NEPiZolIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEXlfXFKSzVyPUCuNFQ2KM7:TR?= MVXTRW5ITVJ?
CaR-1 NELrOpdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFy3XWlKSzVyPUCuNFQ2PDlizszN NV2zb4FbW0GQR1XS
PSN1 MlvKS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2\JSmlEPTB;MD6wOFYxOyEQvF2= NFXwdG5USU6JRWK=
KYSE-510 MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVLJR|UxRTBwMES2OFkh|ryP MX;TRW5ITVJ?
KP-4 M3\ZfWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWfqTnczUUN3ME2wMlA1PzV|IN88US=> NHrTd5BUSU6JRWK=
KYSE-410 NULycWxJT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVPVfZJuUUN3ME2wMlA1Pzd{IN88US=> M3\zTXNCVkeHUh?=
G-402 NEfuNIZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYHJR|UxRTBwMES3PFkh|ryP NGHmVmJUSU6JRWK=
DOK MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXvX[GtpUUN3ME2wMlA1QTB{IN88US=> M3jVe3NCVkeHUh?=
COR-L88 Ml\DS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVnmXo1oUUN3ME2wMlA1QTF{IN88US=> MojLV2FPT0WU
SKG-IIIa MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1;FSWlEPTB;MD6wOFk5PiEQvF2= M{nleXNCVkeHUh?=
AN3-CA NYnrRYg2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWXJR|UxRTBwMEWg{txO M2[2d3NCVkeHUh?=
SW48 M2D3UGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHzKVJhKSzVyPUCuNFUxOzlizszN NX:wPYFvW0GQR1XS
YKG-1 NFfrb|JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHHw[5lKSzVyPUCuNFUxPzFizszN MWnTRW5ITVJ?
KYSE-150 MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYTJR|UxRTBwMEWyN|Uh|ryP NHvoPXJUSU6JRWK=
HuO-3N1 M1HlTmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2Xjb2lEPTB;MD6wOVI{PyEQvF2= M1fLO3NCVkeHUh?=
LB1047-RCC MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYrJR|UxRTBwMEWyPVYh|ryP Ml;vV2FPT0WU
NCI-H2030 NXTYZZlKT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mn7iTWM2OD1yLkC1OFE1KM7:TR?= NYrhR2luW0GQR1XS
YH-13 MoK3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3G0VGlEPTB;MD6wOVczOiEQvF2= NHTVWHVUSU6JRWK=
5637 MV7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmnMTWM2OD1yLkC1O|Qh|ryP NFi5eo9USU6JRWK=
LOXIMVI MlLiS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWPJR|UxRTBwMEW4O|Ih|ryP MXzTRW5ITVJ?
GT3TKB NYe3cWIyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MofxTWM2OD1yLkC1PVQzKM7:TR?= MXvTRW5ITVJ?
TCCSUP MWnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mn\KTWM2OD1yLkC1PVY1KM7:TR?= NYL0T45tW0GQR1XS
EPLC-272H MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NW\ZdY9mUUN3ME2wMlA3OjB3IN88US=> MVvTRW5ITVJ?
LU-99A NYrzWHhCT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEjwOmNKSzVyPUCuNFYzOzdizszN M{njZXNCVkeHUh?=
NCI-H1755 M2fFcWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3\QbWlEPTB;MD6wOlM1OSEQvF2= Ml\pV2FPT0WU
KM12 NVPES3QxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUXMN4JMUUN3ME2wMlA3OzR6IN88US=> NYfR[2tzW0GQR1XS
SF295 NX\RXYoyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEXqdoxKSzVyPUCuNFY1PTJizszN M4K0VXNCVkeHUh?=
MZ2-MEL NInz[WpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MULJR|UxRTBwME[1OVMh|ryP MYHTRW5ITVJ?
HEC-1 NGTpVZVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mn\xTWM2OD1yLkC2OVg5KM7:TR?= M4DLXXNCVkeHUh?=
SW684 M4PETmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGXoRnlKSzVyPUCuNFY2QTFizszN M1TVcXNCVkeHUh?=
SF539 NXz5bnBvT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1fSS2lEPTB;MD6wOlY5OSEQvF2= MYfTRW5ITVJ?
GMS-10 NUDKSI42T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXTJR|UxRTBwME[2PVkh|ryP MXfTRW5ITVJ?
MV-4-11 M3W5V2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NF;WbldKSzVyPUCuNFY5ODNizszN MWfTRW5ITVJ?
HT-29 NGf0PXpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUPJR|UxRTBwME[5NVkh|ryP NXTK[mZKW0GQR1XS
23132-87 MV7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnL6TWM2OD1yLkC2PVUh|ryP MmP1V2FPT0WU
SW620 M1j1UWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYrJR|UxRTBwMEewNlYh|ryP MWXTRW5ITVJ?
HCC1806 M{Tucmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYDzO|JSUUN3ME2wMlA4OTNzIN88US=> MX7TRW5ITVJ?
Hs-578-T NHjV[olIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2PZV2lEPTB;MD6wO|IxQCEQvF2= MUHTRW5ITVJ?
A2058 NHnQOmlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYLEdlhsUUN3ME2wMlA4OjJ6IN88US=> M2TFXHNCVkeHUh?=
MEL-HO NG\C[nRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFP2WFFKSzVyPUCuNFczPTVizszN MUDTRW5ITVJ?
HCC2998 MljOS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmGyTWM2OD1yLkC3N|Q4KM7:TR?= M2TUR3NCVkeHUh?=
HuO9 NVnRR5RJT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MX;JR|UxRTBwMEe1PFkh|ryP NW\ud3NFW0GQR1XS
CAL-39 NVjVV3Z2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2fid2lEPTB;MD6wO|c3PiEQvF2= M4nqXnNCVkeHUh?=
M14 NHPscIxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEnLTmVKSzVyPUCuNFc6OTNizszN M1XqenNCVkeHUh?=
BFTC-909 MnLWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHXGPY9KSzVyPUCuNFc6PjlizszN MofkV2FPT0WU
TE-11 NVrHPW1wT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYC0[VRPUUN3ME2wMlA4QTl4IN88US=> NVfI[mJnW0GQR1XS
TGBC1TKB M{n0[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlPJTWM2OD1yLkC4NFQ{KM7:TR?= M4TCcXNCVkeHUh?=
L-363 MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXXJR|UxRTBwMEiyNFYh|ryP NX7jNmVCW0GQR1XS
A431 MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFjlV3JKSzVyPUCuNFgzOSEQvF2= NEm1Uo9USU6JRWK=
MKN45 MlfQS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MX\JR|UxRTBwMEiyNVkh|ryP NFnlN3BUSU6JRWK=
HT-1080 MljjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4PP[2lEPTB;MD6wPFQ{QSEQvF2= NEO5bWNUSU6JRWK=
OVCAR-8 NYKxWWcyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NX3Q[HpwUUN3ME2wMlA5PjJ{IN88US=> M1nvOXNCVkeHUh?=
LCLC-97TM1 NEf4dXZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1zFTmlEPTB;MD6wPFczQCEQvF2= NW[2bWNMW0GQR1XS
M059J M4PSO2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mnm2TWM2OD1yLkC5NFI4KM7:TR?= MoLCV2FPT0WU
SK-MEL-2 NYrUO3JCT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{fpe2lEPTB;MD6wPVA3KM7:TR?= Mmr2V2FPT0WU
TE-1 MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWGwXFd5UUN3ME2wMlA6OjB2IN88US=> M2rPTnNCVkeHUh?=
KYSE-180 NIfXZVdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXjJR|UxRTBwMEmyOlIh|ryP MX;TRW5ITVJ?
D-247MG NIjIb4tIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4nGc2lEPTB;MD6wPVQ2PSEQvF2= M2LTVXNCVkeHUh?=
8-MG-BA M1ThfWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIXVS2NKSzVyPUCuNFk1PzJizszN NVj4XJByW0GQR1XS
NCI-H1792 NXfJe5pJT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1W2fGlEPTB;MD6wPVYyQCEQvF2= MofNV2FPT0WU
MCF7 NV;2SFRiT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXr6TJJ5UUN3ME2wMlA6Pjd5IN88US=> MlW4V2FPT0WU
NCI-H2122 NVWxbm1TT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWDJR|UxRTBwMEm3OFUh|ryP MoTUV2FPT0WU
EFO-27 MUjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1\xUmlEPTB;MD6wPVk6PyEQvF2= MUXTRW5ITVJ?
LB2241-RCC M1fZfmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlXTTWM2OD1yLkGwNFU1KM7:TR?= MkTrV2FPT0WU
SN12C MXTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWTJR|UxRTBwMUCxNFch|ryP NVjUZpE2W0GQR1XS
A498 MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{G5VGlEPTB;MD6xNFE5KM7:TR?= MU\TRW5ITVJ?
PANC-03-27 M2Px[Wdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFnhSXBKSzVyPUCuNVAzQDZizszN M{j4c3NCVkeHUh?=
NCI-H1581 M1LrWGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXLNO3NmUUN3ME2wMlExOjlizszN M4DhUXNCVkeHUh?=
U-87-MG MWDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkXvTWM2OD1yLkGwN|A4KM7:TR?= NVTJOoJvW0GQR1XS
G-401 NX\WeHl3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEjodoNKSzVyPUCuNVA{PTNizszN M1\PVHNCVkeHUh?=
SiHa MmHuS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2PlfmlEPTB;MD6xNFQ5PiEQvF2= MoHPV2FPT0WU
U251 NUDKdZNRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGrRZlRKSzVyPUCuNVA2OjVizszN MUnTRW5ITVJ?
MMAC-SF M1XWVmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHPCfZhKSzVyPUCuNVA2OzFizszN NFPYZm5USU6JRWK=
BB65-RCC NHq4R|RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIX0TJhKSzVyPUCuNVA2PTRizszN MX\TRW5ITVJ?
NKM-1 NWXOWGxCT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVT5S2o1UUN3ME2wMlExPjZ4IN88US=> NWjjTXRUW0GQR1XS
HD-MY-Z MoSxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGfWSGpKSzVyPUCuNVA5PzNizszN MlT4V2FPT0WU
TGBC11TKB NF6weJZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYrJR|UxRTBwMUC5NFMh|ryP MkTGV2FPT0WU
COLO-679 MkLOS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mm\3TWM2OD1yLkGxNlEyKM7:TR?= NIfBeHRUSU6JRWK=
TE-8 MXjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlviTWM2OD1yLkGxNlY1KM7:TR?= NV[0[2U3W0GQR1XS
SK-MEL-28 NFyzXItIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHrTVJRKSzVyPUCuNVE{OjFizszN MkiwV2FPT0WU
SH-4 NVHIcWhDT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGPte|ZKSzVyPUCuNVE{PTZizszN M{P2XXNCVkeHUh?=
KALS-1 M1HlTmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MofpTWM2OD1yLkGxN|k{KM7:TR?= M3z0THNCVkeHUh?=
RKO MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEDZZ|NKSzVyPUCuNVE4PjRizszN MoDwV2FPT0WU
OMC-1 NEiy[Y1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIjoUIFKSzVyPUCuNVE4QTdizszN NWnSd|ZmW0GQR1XS
BT-549 MmLhS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MULJR|UxRTBwMUG3PVkh|ryP MXnTRW5ITVJ?
NCI-H28 NXrmdFAzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MX3JR|UxRTBwMUG4NVch|ryP MonBV2FPT0WU
RXF393 M{m1Wmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWPVT2J{UUN3ME2wMlEyQTh{IN88US=> M360VHNCVkeHUh?=
COLO-829 NXnQbnM2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXTJR|UxRTBwMUKwNFUh|ryP NFTrXGRUSU6JRWK=
HMV-II NH2zemhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NV:3Z5d[UUN3ME2wMlEzODJizszN NF7OTnlUSU6JRWK=
SW1990 NYr6U|ZMT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWT3XodDUUN3ME2wMlEzOTV5IN88US=> MU\TRW5ITVJ?
NCI-H1437 NW\3V5JzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MojBTWM2OD1yLkGyNVU4KM7:TR?= MUfTRW5ITVJ?
SNB75 NF;SVHdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlfpTWM2OD1yLkGyNVY6KM7:TR?= M1j6dXNCVkeHUh?=
EW-3 M4nVbGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1:wW2lEPTB;MD6xNlY3OSEQvF2= MWrTRW5ITVJ?
SAS MkjlS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmTwTWM2OD1yLkGyOlkh|ryP NF7ObolUSU6JRWK=
NCI-H1666 M{fD[2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGPCUGdKSzVyPUCuNVI4PzRizszN M3TMeXNCVkeHUh?=
A375 NGnFZYlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVvYNIprUUN3ME2wMlEzPzd6IN88US=> MUnTRW5ITVJ?
CAMA-1 NYruSHVKT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{\wfGlEPTB;MD6xNlkzPCEQvF2= NITnU5dUSU6JRWK=
HuP-T4 NFLqOlBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{PjdWlEPTB;MD6xNlk1OyEQvF2= NIXhN2dUSU6JRWK=
NCI-H292 NH\JRlhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoXKTWM2OD1yLkGzNVEh|ryP MoDDV2FPT0WU
PC-14 Mn\DS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MX7JR|UxRTBwMUOyNVEh|ryP M2jrXXNCVkeHUh?=
BPH-1 MnXtS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUDJR|UxRTBwMUO0NUDPxE1? NWTZdZFvW0GQR1XS
GAK NVPJZWtDT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmPZTWM2OD1yLkGzOVY4KM7:TR?= NX7tUJpsW0GQR1XS
VMRC-RCZ NGHxdYdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mln0TWM2OD1yLkGzO|YzKM7:TR?= M4jrcXNCVkeHUh?=
SK-MEL-24 M{HNfWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1H0e2lEPTB;MD6xN|g4KM7:TR?= MX7TRW5ITVJ?
LB831-BLC NH\WO5pIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGrjNIdKSzVyPUCuNVM5QDNizszN NUfKO4duW0GQR1XS
NCI-H2452 MkLaS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3zoTWlEPTB;MD6xN|k2PiEQvF2= M{jVeHNCVkeHUh?=
RT-112 Mn\jS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWXBUGdjUUN3ME2wMlE1ODN3IN88US=> NHnVeYJUSU6JRWK=
GP5d MnXZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHy3UnVKSzVyPUCuNVQyODRizszN M17SSnNCVkeHUh?=
LC-2-ad NHv5So5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M33ueWlEPTB;MD6xOFEzOSEQvF2= M3\HcHNCVkeHUh?=
MPP-89 M3nQNWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{iyUWlEPTB;MD6xOFEzPSEQvF2= MXHTRW5ITVJ?
NUGC-3 M1rT[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHnkUZFKSzVyPUCuNVQ1PzhizszN M13IeHNCVkeHUh?=
GI-1 MoDXS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3fYc2lEPTB;MD6xOFU2QCEQvF2= MYLTRW5ITVJ?
HCC1419 Ml3kS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Ml7DTWM2OD1yLkG0OVc3KM7:TR?= MoLSV2FPT0WU
SW1573 M4TRdWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlLQTWM2OD1yLkG0O|U5KM7:TR?= MkLlV2FPT0WU
NCI-H2347 NI\KfIdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWHzVmpmUUN3ME2wMlE1QDN7IN88US=> MY\TRW5ITVJ?
Mewo NVHQTIp2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWT5S4tuUUN3ME2wMlE1QDh7IN88US=> MnzwV2FPT0WU
639-V NGj5bXVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYPJR|UxRTBwMUWwNVMh|ryP NEX5PItUSU6JRWK=
AsPC-1 NUnKUoloT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYLJR|UxRTBwMUWyNlUh|ryP NX:1bIJbW0GQR1XS
NCI-H1648 MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mn;qTWM2OD1yLkG1NlMzKM7:TR?= M1:5[nNCVkeHUh?=
786-0 NUe0OIFqT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2riOmlEPTB;MD6xOVM5OSEQvF2= NIq0eVNUSU6JRWK=
ETK-1 MkS5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3vHRWlEPTB;MD6xOVkh|ryP MVTTRW5ITVJ?
BxPC-3 NWDU[olmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MonJTWM2OD1yLkG1PVY3KM7:TR?= MoTXV2FPT0WU
CAL-62 M172T2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFi3VFdKSzVyPUCuNVYyPjlizszN M{\USnNCVkeHUh?=
HCC1937 M4L5NGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWjsSYV2UUN3ME2wMlE3Ojd3IN88US=> M2\oXnNCVkeHUh?=
NCI-H1299 NEPaOpdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFPTeWxKSzVyPUCuNVYzQDVizszN M1rQbXNCVkeHUh?=
SW1088 M4r2[Gdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MljtTWM2OD1yLkG2OFE{KM7:TR?= NInYdoxUSU6JRWK=
FTC-133 NVfnXnR{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUHU[XJZUUN3ME2wMlE3PTRizszN M1nXO3NCVkeHUh?=
OC-314 M1vpRmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYnIVHMxUUN3ME2wMlE3PjlizszN NYPYZ3BbW0GQR1XS
SCC-9 MojUS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1jNTGlEPTB;MD6xOlcyPiEQvF2= M1TGcXNCVkeHUh?=
HT-1376 NH[2TFVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2\1emlEPTB;MD6xOlk{PiEQvF2= MUTTRW5ITVJ?
U-2-OS M1\2TWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYfJR|UxRTBwMUexO|Mh|ryP NUm3RW5CW0GQR1XS
COLO-824 M4nHeWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3\0NmlEPTB;MD6xO|I6PCEQvF2= MXXTRW5ITVJ?
BB30-HNC MonmS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{TmbGlEPTB;MD6xO|M{KM7:TR?= MX\TRW5ITVJ?
NCI-H2087 M13BWmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVXHc2RbUUN3ME2wMlE4OzZ6IN88US=> NHHWb49USU6JRWK=
NCI-H2170 MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmH2TWM2OD1yLkG3OVM3KM7:TR?= NVrxNHVYW0GQR1XS
SK-OV-3 MnHNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXLhR2xNUUN3ME2wMlE4PTdzIN88US=> MnG5V2FPT0WU
MZ7-mel NGXNVpNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NH7pOYRKSzVyPUCuNVc3PDlizszN NHPOVndUSU6JRWK=
NCI-H650 NEizcXJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1TzWWlEPTB;MD6xO|Y5OiEQvF2= NFrHWFlUSU6JRWK=
KOSC-2 MV7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M17vWmlEPTB;MD6xO|c{PCEQvF2= M{Hh[3NCVkeHUh?=
SCC-4 MlexS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYnJR|UxRTBwMUe3O|ch|ryP M3rFPXNCVkeHUh?=
MDA-MB-157 MmizS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYS0NY1bUUN3ME2wMlE5ODh{IN88US=> M4HzbXNCVkeHUh?=
KYSE-520 NEfncYVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWPJR|UxRTBwMUiyJO69VQ>? MkXUV2FPT0WU
LK-2 M1fUfWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWLJR|UxRTBwMUizNFMh|ryP MoKwV2FPT0WU
KNS-81-FD MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4i5cWlEPTB;MD6xPFM6PCEQvF2= NFHiTphUSU6JRWK=
IGROV-1 NIX2bHZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGm2S2dKSzVyPUCuNVg1PDNizszN M2ixbnNCVkeHUh?=
DEL MnvWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Ml3qTWM2OD1yLkG4OFUh|ryP MkD6V2FPT0WU
NCI-H1395 M{HPXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NY\uUJJ3UUN3ME2wMlE5Pjh{IN88US=> MULTRW5ITVJ?
JEG-3 NFLod|lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVyxW2puUUN3ME2wMlE5PzB3IN88US=> NYXuSpl7W0GQR1XS
BCPAP MYXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmLXTWM2OD1yLkG4PFczKM7:TR?= NGfRblNUSU6JRWK=
CAL-27 MljYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2nsWWlEPTB;MD6xPVAzOiEQvF2= NUPNN21VW0GQR1XS
RD MkjLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVjZUWtHUUN3ME2wMlE6OTF|IN88US=> NUS5clMyW0GQR1XS
RVH-421 NEnYbFFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEf3TlhKSzVyPUCuNVkyOTZizszN NIfZcphUSU6JRWK=
Capan-2 NILJPWhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYjZNGJ7UUN3ME2wMlE6OjV4IN88US=> MmjBV2FPT0WU
COLO-680N MlPUS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEXWTXpKSzVyPUCuNVk{PjRizszN NX7wWVA5W0GQR1XS
NCI-H1650 NXWzSWllT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkfmTWM2OD1yLkKwNFU4KM7:TR?= M4P3SHNCVkeHUh?=
SBC-5 M3PVN2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M37FTWlEPTB;MD6yNFEyQCEQvF2= M{HhSXNCVkeHUh?=
U031 Mn\zS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4fDeWlEPTB;MD6yNFU1PyEQvF2= NFnve2hUSU6JRWK=
S-117 NYDKWFg1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHrLdldKSzVyPUCuNlA2PjRizszN NXnQVlFsW0GQR1XS
DoTc2-4510 NILH[nFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4PxS2lEPTB;MD6yNFc3QSEQvF2= Mn61V2FPT0WU
AM-38 MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{K5bWlEPTB;MD6yNFg1QCEQvF2= M{PUVnNCVkeHUh?=
A172 MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEHSd5NKSzVyPUCuNlExOjJizszN MYLTRW5ITVJ?
HPAF-II NX3pXGpyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4PrbmlEPTB;MD6yNVI3PCEQvF2= NFjLPVNUSU6JRWK=
769-P NEXjclhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2\WcmlEPTB;MD6yNVI5KM7:TR?= NY[5e|ZHW0GQR1XS
MFE-280 MUjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVfYN3ppUUN3ME2wMlIyOjl6IN88US=> MlzjV2FPT0WU
TE-9 NVTDcmFFT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4LX[WlEPTB;MD6yNVc5PiEQvF2= NHfCVlFUSU6JRWK=
C2BBe1 NH3OW|VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NX[2SpdMUUN3ME2wMlIzOTlizszN MVnTRW5ITVJ?
EoL-1-cell Mn7GS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M33GWGlEPTB;MD6yNlIxOyEQvF2= NX7aNlN[W0GQR1XS
G-361 Mn7XS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGLZSFVKSzVyPUCuNlI3QDJizszN NXjpc2lpW0GQR1XS
KYSE-270 M1zzbmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M13GbGlEPTB;MD6yN|A5PCEQvF2= NWHDPWJHW0GQR1XS
TK10 MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWPJR|UxRTBwMkOxNVch|ryP NIHoSIZUSU6JRWK=
ML-2 NITBWodIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnfTTWM2OD1yLkKzNVE6KM7:TR?= NUXqNFV3W0GQR1XS
MHH-ES-1 NEXr[JRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWjCb3lSUUN3ME2wMlI{PjhzIN88US=> NYXZT4lwW0GQR1XS
BHY MlXRS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Ml7ETWM2OD1yLkKzOlkyKM7:TR?= MmK5V2FPT0WU
LS-513 MX\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Ml;RTWM2OD1yLkKzPVYyKM7:TR?= M1rK[3NCVkeHUh?=
COLO-678 M13Hcmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXrDcXp4UUN3ME2wMlI1ODR2IN88US=> M1\CVnNCVkeHUh?=
NCI-H747 MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYrJR|UxRTBwMkSxOlkh|ryP MXTTRW5ITVJ?
K5 MoS1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MofHTWM2OD1yLkK0N|gh|ryP MkHoV2FPT0WU
OS-RC-2 NXXvVnBGT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlvmTWM2OD1yLkK0OVA6KM7:TR?= MVjTRW5ITVJ?
KINGS-1 M{S1eGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mn\4TWM2OD1yLkK0OVI6KM7:TR?= MV;TRW5ITVJ?
SCC-25 NH7vUZdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEf0RWlKSzVyPUCuNlQ2PjNizszN Ml7yV2FPT0WU
CAPAN-1 MX7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnX2TWM2OD1yLkK0O|g{KM7:TR?= MkfVV2FPT0WU
ESS-1 NFXGfFhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NULxXmw2UUN3ME2wMlI1QDB3IN88US=> M3G4UnNCVkeHUh?=
TE-6 M2jURmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVfySFdPUUN3ME2wMlI2PzVizszN MXzTRW5ITVJ?
LB2518-MEL MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmLDTWM2OD1yLkK1O|c4KM7:TR?= NHrwNo1USU6JRWK=
COLO-800 M1iyd2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M17PUGlEPTB;MD6yOVgyOiEQvF2= MV;TRW5ITVJ?
LU-134-A M2L0PGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MofiTWM2OD1yLkK2NVM3KM7:TR?= M4\STnNCVkeHUh?=
NCI-H1155 M{L2eWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVLJR|UxRTBwMk[xOlIh|ryP MorpV2FPT0WU
MFM-223 NFfxNFdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXe0R49JUUN3ME2wMlI3OzZ|IN88US=> MnLUV2FPT0WU
HTC-C3 MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mo\vTWM2OD1yLkK2OVA3KM7:TR?= M3HHbHNCVkeHUh?=
HCT-116 NH\KSFJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXfYZYR2UUN3ME2wMlI3PTl7IN88US=> NIXZUmlUSU6JRWK=
Ca-Ski NWLuRoFRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYHJR|UxRTBwMk[2O|gh|ryP M3myV3NCVkeHUh?=
SBC-1 NV\KUIQ1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MY\JR|UxRTBwMk[3OFIh|ryP M1\DZnNCVkeHUh?=
NB69 NGfnUGdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGnTRotKSzVyPUCuNlcxQDdizszN NWP4eIRwW0GQR1XS
J82 NXPPe5VQT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnzITWM2OD1yLkK3NlY2KM7:TR?= NGnKfJpUSU6JRWK=
U-118-MG NFLUblFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEnoUo1KSzVyPUCuNlc2PzlizszN MUHTRW5ITVJ?
NCI-H1355 NYfZdnVUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M33Dd2lEPTB;MD6yPFA4PCEQvF2= MV\TRW5ITVJ?
NCI-H1048 NHK1TmlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUPJR|UxRTBwMki5OVYh|ryP MmjnV2FPT0WU
SW954 MmfMS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGHRWVhKSzVyPUCuNlkzOjdizszN M3PZfnNCVkeHUh?=
NMC-G1 M3jHNGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGmyXlVKSzVyPUCuNlkzPzdizszN M2G5SnNCVkeHUh?=
SW1710 MmjWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1LscGlEPTB;MD6yPVQ6PCEQvF2= M1O2S3NCVkeHUh?=
KY821 M{j4TWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnTzTWM2OD1yLkK5PFczKM7:TR?= NFvXVFRUSU6JRWK=
HCC38 NVLaVo17T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MV;JR|UxRTBwM{CwO|gh|ryP NGTRb49USU6JRWK=
NCI-SNU-5 MoiyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVTJR|UxRTBwM{C1OEDPxE1? NY[2VGpMW0GQR1XS
ES8 NV7qSpQ6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3;UR2lEPTB;MD6zNFc5PCEQvF2= MX\TRW5ITVJ?
COLO-792 MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFrEWHNKSzVyPUCuN|EzPTFizszN MlXwV2FPT0WU
BFTC-905 M4i0cGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2LzfWlEPTB;MD6zNVUzOSEQvF2= M3TqRnNCVkeHUh?=
ChaGo-K-1 M4HvWWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGjwWYJKSzVyPUCuN|E4OTVizszN M3fI[XNCVkeHUh?=
Daoy MUHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGK2RldKSzVyPUCuN|E4OjNizszN MVvTRW5ITVJ?
SJSA-1 MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWLJR|UxRTBwM{G4OFch|ryP NGCxSohUSU6JRWK=
KNS-62 NF;lcY9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYfndGFUUUN3ME2wMlMzODh6IN88US=> NGr0V2NUSU6JRWK=
CAKI-1 NYH5bJBTT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWfMUGdQUUN3ME2wMlMzOTFzIN88US=> M4W1SHNCVkeHUh?=
UACC-62 NFnRNJJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NX3Q[HI1UUN3ME2wMlMzOjJ5IN88US=> NEH5O2VUSU6JRWK=
HuCCT1 MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWDJR|UxRTBwM{KyPFMh|ryP M1m2eHNCVkeHUh?=
CTB-1 MmLWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGLje29KSzVyPUCuN|I4PTNizszN MV;TRW5ITVJ?
NTERA-S-cl-D1 MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGfZNYVKSzVyPUCuN|I5OzZizszN Mn7LV2FPT0WU
T-24 M4GycGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M17WTmlEPTB;MD6zN|E2QSEQvF2= NFfab4RUSU6JRWK=
KYSE-70 MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{Tw[2lEPTB;MD6zN|I5OyEQvF2= M3\tZXNCVkeHUh?=
SW626 MULHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXXI[YJiUUN3ME2wMlM{PTN{IN88US=> MkXKV2FPT0WU
LB996-RCC M4TKUWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkXLTWM2OD1yLkOzOlE6KM7:TR?= MlzVV2FPT0WU
DMS-273 NF73Z41Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUDrcGFOUUN3ME2wMlM{QTF4IN88US=> MYrTRW5ITVJ?
SW1783 MX\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4HGSmlEPTB;MD6zN|k6PyEQvF2= M2\tdHNCVkeHUh?=
KU812 M372fmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEW5fmRKSzVyPUCuN|QxOzhizszN Mmr2V2FPT0WU
HSC-2 NFvsUIhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUPOOYhWUUN3ME2wMlM1ODV|IN88US=> NVHNOHFoW0GQR1XS
A3-KAW NWnE[phMT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NX7XboFmUUN3ME2wMlM1OTZ{IN88US=> NYTJfWZZW0GQR1XS
COLO-684 M4rqXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MY\JR|UxRTBwM{S1NFEh|ryP MUPTRW5ITVJ?
NCI-H2405 NWD5U3IzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYjJR|UxRTBwM{S2N|Eh|ryP NHTINFZUSU6JRWK=
NCI-H2228 MnrSS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWnJR|UxRTBwM{WzOVch|ryP M4jFd3NCVkeHUh?=
NB13 NF7iUGVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEjkdGpKSzVyPUCuN|Y5OjlizszN MUjTRW5ITVJ?
no-11 M2iyRWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXrsfJgzUUN3ME2wMlM3QTVizszN M2W5PHNCVkeHUh?=
DK-MG NIjmPHdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoL2TWM2OD1yLkO3NVg5KM7:TR?= M3;hUHNCVkeHUh?=
NBsusSR M{DJfmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGO0V2FKSzVyPUCuN|czQDVizszN Mn;CV2FPT0WU
KP-N-YS NGfUc4JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4TmWmlEPTB;MD6zO|Q3OyEQvF2= NVr6PJY5W0GQR1XS
CFPAC-1 M1XkSWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUfUTWZCUUN3ME2wMlM4PTF6IN88US=> MYrTRW5ITVJ?
KARPAS-45 Ml3zS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGXzcXFKSzVyPUCuN|c5PjJizszN MojBV2FPT0WU
NCI-H1793 MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2\ETGlEPTB;MD6zPFUyKM7:TR?= M{XyeHNCVkeHUh?=
HCE-T MkP0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4e3bWlEPTB;MD6zPFYxOyEQvF2= M3;FOHNCVkeHUh?=
NCI-H520 NILLTHZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1r2SWlEPTB;MD6zPFcxOyEQvF2= MlfpV2FPT0WU
HCC2157 NE\CZYxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4myT2lEPTB;MD6zPFc5OSEQvF2= NV7IZpV1W0GQR1XS
EW-18 M1SzUGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEXtTm5KSzVyPUCuN|g6PDFizszN MXvTRW5ITVJ?
RO82-W-1 NYDGfFQ5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXjJR|UxRTBwM{m2PVkh|ryP MXzTRW5ITVJ?
HuP-T3 MULHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXPyNI1WUUN3ME2wMlQxOTR|IN88US=> NWTNfFFyW0GQR1XS
PANC-10-05 MnuzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Ml7iTWM2OD1yLkSxNVch|ryP NG[5ZZZUSU6JRWK=
NCI-H1703 MnTlS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYDFe|JVUUN3ME2wMlQyPDR4IN88US=> Mom4V2FPT0WU
TE-10 MnixS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NX;qcpBXUUN3ME2wMlQyPDR5IN88US=> NEPEeZlUSU6JRWK=
HOS NWDjVVA{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYDJR|UxRTBwNEG2PFIh|ryP NIn2[FZUSU6JRWK=
LN-405 NFLtPIxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFj2dJJKSzVyPUCuOFE3QDdizszN NG\ONVVUSU6JRWK=
A427 MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4m3V2lEPTB;MD60NVk5OSEQvF2= MlPoV2FPT0WU
CAL-12T MmDJS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFWybYhKSzVyPUCuOFI4QCEQvF2= M3z3PHNCVkeHUh?=
SW756 NXL1UIQ4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1K0WmlEPTB;MD60OFE5OyEQvF2= NInDVXlUSU6JRWK=
YAPC NUD6bmhST3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGnJW|RKSzVyPUCuOFUxQCEQvF2= MojuV2FPT0WU
GOTO MlTyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Ml\sTWM2OD1yLkS1NVYh|ryP NGLsc5RUSU6JRWK=
C3A MlixS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M165VGlEPTB;MD60OVQ{PyEQvF2= MljWV2FPT0WU
UM-UC-3 Mnr2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYnyOFBpUUN3ME2wMlQ2PDdizszN MUnTRW5ITVJ?
NCI-H1573 NIrRZolIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWrJR|UxRTBwNEW1Olkh|ryP NU\zWYVbW0GQR1XS
LS-411N MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWDJR|UxRTBwNE[1Nlch|ryP M1T2OXNCVkeHUh?=
COR-L23 MlLPS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIm0cpdKSzVyPUCuOFY4PjRizszN MlXLV2FPT0WU
HCE-4 NVexXmNDT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXHJR|UxRTBwNEe0OFYh|ryP MnL1V2FPT0WU
NCI-H2291 NXHneJZNT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4exbmlEPTB;MD60O|g6PiEQvF2= NV;nbo9FW0GQR1XS
A101D NFvGb|ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYTINIRYUUN3ME2wMlQ5ODV|IN88US=> NXPwRpVFW0GQR1XS
HT-3 MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnPjTWM2OD1yLkS4NlE4KM7:TR?= M2flVnNCVkeHUh?=
HOP-62 NEP4dplIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUjJR|UxRTBwNEm4OlUh|ryP NWD5UVlzW0GQR1XS
PC-3 M3zDcmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1W5PWlEPTB;MD61NVUxPyEQvF2= MULTRW5ITVJ?
CTV-1 NX7UfWVNT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoSxTWM2OD1yLkWyOlY6KM7:TR?= MUfTRW5ITVJ?
PANC-08-13 MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFPqbYtKSzVyPUCuOVMyPzdizszN MlezV2FPT0WU
CAL-120 MXjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFu1PZNKSzVyPUCuOVM{QTlizszN NVLCbpFjW0GQR1XS
UMC-11 NYLUSXdOT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFjCXnpKSzVyPUCuOVUzOzRizszN MorHV2FPT0WU
MSTO-211H MmOzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEfMO4VKSzVyPUCuOVU4PjJizszN NEXC[WxUSU6JRWK=
NCI-H2126 NWrFWnZrT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWS3PFNUUUN3ME2wMlU3QDF3IN88US=> M3S0SnNCVkeHUh?=
SNU-C2B NIjBcVFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmDLTWM2OD1yLkW3PVc4KM7:TR?= MnPRV2FPT0WU
DBTRG-05MG MoDIS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlnpTWM2OD1yLkW4NFU{KM7:TR?= NHLvRoRUSU6JRWK=
MKN1 M{[3OGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MX3JR|UxRTBwNUi3PFMh|ryP M2XreXNCVkeHUh?=
ES3 M37zd2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWTJR|UxRTBwNUmxNlQh|ryP NWmz[Y9zW0GQR1XS
OVCAR-3 MlfGS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnvFTWM2OD1yLkW5N|QyKM7:TR?= NV[0S3o5W0GQR1XS
ACHN NYjJZm1ST3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVrHV3ZIUUN3ME2wMlYxPTZ7IN88US=> MUTTRW5ITVJ?
SW872 M3PLZ2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWXJR|UxRTBwNkC3OlMh|ryP NF3hTmlUSU6JRWK=
CP66-MEL NUG3RZVxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MULJR|UxRTBwNkC5Olkh|ryP NVf4[Iw3W0GQR1XS
NCI-H661 NXP4Zo4{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVHJR|UxRTBwNkGxNFQh|ryP NXvtO3ZEW0GQR1XS
UACC-893 MVHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXzJR|UxRTBwNkO2PFEh|ryP M2PLXnNCVkeHUh?=
JVM-3 NX7XSYwzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVLOUW57UUN3ME2wMlY{QDB2IN88US=> M3uzZ3NCVkeHUh?=
SF268 NWTBc|JwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3zWNGlEPTB;MD62OFM1QSEQvF2= M3fKWnNCVkeHUh?=
OCI-AML2 M{TVWmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3ft[GlEPTB;MD62OVM6PyEQvF2= NWjQW4E2W0GQR1XS
RPMI-8226 NHHz[lBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NH\WU2VKSzVyPUCuOlY{OjNizszN NIXvcmFUSU6JRWK=
MKN28 Ml3zS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmK2TWM2OD1yLk[2OlI1KM7:TR?= M2\FeXNCVkeHUh?=
MDA-MB-453 MYjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2O5SWlEPTB;MD62O|E5KM7:TR?= M3KwSXNCVkeHUh?=
BV-173 NVzueGxCT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWjJR|UxRTBwNki2O|kh|ryP MWHTRW5ITVJ?
NCI-H358 NG\6WIZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGHvWW5KSzVyPUCuOlg4OjZizszN Mmj4V2FPT0WU
NCI-H1651 MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlvHTWM2OD1yLkeg{txO M4D1ZXNCVkeHUh?=
MDA-MB-415 NHS4NlZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlfOTWM2OD1yLkewPFI6KM7:TR?= MW\TRW5ITVJ?
8305C M1XZWmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{TXTWlEPTB;MD63NlQ6QCEQvF2= M4XwR3NCVkeHUh?=
EFM-19 NVThNWJuT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1;QTGlEPTB;MD63N|Y4OSEQvF2= M4L0bXNCVkeHUh?=
RERF-LC-MS M3m0Omdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWrJR|UxRTBwN{S2NVMh|ryP NYPrcWQ4W0GQR1XS
A388 NYHvWlc1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYHBToJiUUN3ME2wMlc3PDZ5IN88US=> Mo\uV2FPT0WU
GI-ME-N MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NX3LPYE2UUN3ME2wMlc4OjN3IN88US=> Mk\JV2FPT0WU
IGR-1 NISxTFdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NV;SW4ozUUN3ME2wMlc6ODR|IN88US=> MoXsV2FPT0WU
LNCaP-Clone-FGC NH[wbG5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoLuTWM2OD1yLkiwNFA1KM7:TR?= MVjTRW5ITVJ?
SK-MEL-3 M2nybmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M331RmlEPTB;MD64NVUxQCEQvF2= NEnMcnRUSU6JRWK=
UACC-257 NV;NZ5NFT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFnqVlRKSzVyPUCuPFIzOzFizszN NGDEdFhUSU6JRWK=
OE33 NH\ueVNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUXM[IRMUUN3ME2wMlg2OTBzIN88US=> MVvTRW5ITVJ?
QIMR-WIL NYLZV3VzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFrGVoRKSzVyPUCuPFUyPDFizszN NEK4cJZUSU6JRWK=
NCI-H2009 NUWyVXgyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmnVTWM2OD1yLki1N|EyKM7:TR?= M3XJenNCVkeHUh?=
NCI-H522 NUfRN4lMT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWexPXV7UUN3ME2wMlg4Pzh|IN88US=> MYDTRW5ITVJ?
Saos-2 MoL0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MV\JR|UxRTBwOEe4O|Eh|ryP M2HMVHNCVkeHUh?=
NB17 NGGwbHNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mn3BTWM2OD1yLki4NFI2KM7:TR?= MY\TRW5ITVJ?
D-392MG M4Dzb2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnXZTWM2OD1yLki5N|U3KM7:TR?= Mki5V2FPT0WU
SHP-77 NVHTcWh2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXvCXIN6UUN3ME2wMlkxPDh3IN88US=> MoX2V2FPT0WU
SK-MEL-30 MnvSS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWn2cJp3UUN3ME2wMlkyOTh3IN88US=> NVHBNGlVW0GQR1XS
GCIY NWrm[WZ2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXzwTFlJUUN3ME2wMlkyQDR|IN88US=> NVraNVRIW0GQR1XS
HCC70 NEnKWnNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXzJR|UxRTBwOUKwOVkh|ryP MUjTRW5ITVJ?
LU-65 NGPmW41Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYrJR|UxRTBwOUK1PVEh|ryP Ml3HV2FPT0WU
NCI-H1563 M333SGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVPNZm5CUUN3ME2wMlk1QDZ3IN88US=> MoXTV2FPT0WU
KURAMOCHI NX;4RllWT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXnJR|UxRTBwOUWxPVIh|ryP M33oUXNCVkeHUh?=
PA-1 MlLsS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHPIfoFKSzVyPUCuPVU1OjRizszN NHvWOItUSU6JRWK=
NOS-1 MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIi2XZNKSzVyPUCuPVc1QDlizszN MlzvV2FPT0WU
NCI-H69 M2Kzfmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlTOTWM2OD1yLkm3OlM1KM7:TR?= MW\TRW5ITVJ?
KYSE-450 MljuS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4HHc2lEPTB;MD65PFYzPiEQvF2= NXrWdoxLW0GQR1XS
8505C M1;1SGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXrJR|UxRTBwOUm5PFIh|ryP NVvnO3BlW0GQR1XS
TGBC24TKB NETNeHJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXrJR|UxRTFwMECwPFQh|ryP M4jae3NCVkeHUh?=
PFSK-1 M3;5S2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Ml:wTWM2OD1zLkCxOFI5KM7:TR?= MWrTRW5ITVJ?
EKVX M3nrbGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2LMdmlEPTB;MT6wN|EzOSEQvF2= M{O0NHNCVkeHUh?=
RCM-1 NV\pR2lVT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXX0PZJlUUN3ME2xMlA2PTB5IN88US=> M1XL[XNCVkeHUh?=
SW900 M3L1XGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MW\JR|UxRTFwMEe4N{DPxE1? M1fJXHNCVkeHUh?=
D-542MG MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkntTWM2OD1zLkC3PFU2KM7:TR?= MkLtV2FPT0WU
SK-PN-DW MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmnYTWM2OD1zLkGwNFU3KM7:TR?= MmDiV2FPT0WU
NCI-H727 MUjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmXhTWM2OD1zLkGwNVU1KM7:TR?= M1S0WnNCVkeHUh?=
SW837 NWPtWnh1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVzJR|UxRTFwMUC5OVQh|ryP Ml:3V2FPT0WU
BT-20 NF\TUXVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoK4TWM2OD1zLkGxNlA1KM7:TR?= Moi1V2FPT0WU
RH-18 NGDTXIJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXfpdYlbUUN3ME2xMlE{OTB|IN88US=> NFHIWmJUSU6JRWK=
TE-12 MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFLzcGVKSzVyPUGuNVM{OzNizszN Mmi3V2FPT0WU
NB10 Mn7SS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2jzd2lEPTB;MT6xN|M1PCEQvF2= NXjP[JdtW0GQR1XS
AU565 M4nUSmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4r4TGlEPTB;MT6xOVk4OyEQvF2= M1e5[3NCVkeHUh?=
OAW-42 MV7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mnf2TWM2OD1zLkG4N|A3KM7:TR?= NV7kRXBuW0GQR1XS
DJM-1 NXXpV2tDT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHjZbYNKSzVyPUGuNVk5QDFizszN MUjTRW5ITVJ?
HH NGXVcolIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVfJWVJVUUN3ME2xMlI{QDNzIN88US=> M{jDZ3NCVkeHUh?=
LAMA-84 M2fkWWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlPBTWM2OD1zLkK3N|k1KM7:TR?= M2KxfHNCVkeHUh?=
KNS-42 MULHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUnUN3VbUUN3ME2xMlMxOjl4IN88US=> MmPEV2FPT0WU
NCI-H2052 M4fuW2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYLJR|UxRTFwM{C1NFch|ryP MXrTRW5ITVJ?
MLMA MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M37EUGlEPTB;MT6zNlQxPyEQvF2= M1W0R3NCVkeHUh?=
NB12 NXj2b|BNT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoLaTWM2OD1zLkO1OlM3KM7:TR?= NHq2cIlUSU6JRWK=
NCI-H1838 M1P5cmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M37uO2lEPTB;MT6zOlMxPiEQvF2= NGP2dnZUSU6JRWK=
NCI-H526 MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUfHfIhoUUN3ME2xMlM4QDV|IN88US=> MkDyV2FPT0WU
LS-123 NVrySVRCT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXjJR|UxRTFwM{mwPVQh|ryP MoXvV2FPT0WU
HDLM-2 NVzQTXMyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mo[zTWM2OD1zLkO5NlcyKM7:TR?= MVzTRW5ITVJ?
MC-IXC NHiwNIJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVfkeJZyUUN3ME2xMlQzOzdzIN88US=> MUXTRW5ITVJ?
HCT-15 NFTXS3lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NY\vVGY{UUN3ME2xMlQ{ODZ6IN88US=> Mn3LV2FPT0WU
NCI-H596 MlvpS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXXJR|UxRTFwNEWwOlEh|ryP NHrXU41USU6JRWK=
ZR-75-30 NH3YfGpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mny4TWM2OD1zLkS3NFgzKM7:TR?= M2rZe3NCVkeHUh?=
A704 NITNXJdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFf5XmRKSzVyPUGuOlY2PjNizszN NWjyO3dVW0GQR1XS
OVCAR-4 M{\TOWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MU\JR|UxRTFwNkm2NFch|ryP NFjhbXZUSU6JRWK=
SW1417 MkGzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVe0[pNjUUN3ME2xMlczQDR7IN88US=> MYTTRW5ITVJ?
CAS-1 M2TR[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MV\JR|UxRTFwN{O5N|Yh|ryP NYG2UGpoW0GQR1XS
IST-SL1 NFW2fIlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUfOSokzUUN3ME2xMlc6PzV7IN88US=> MWnTRW5ITVJ?
A253 NGrCWZJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3KzcGlEPTB;MT64NlI{QSEQvF2= MYTTRW5ITVJ?
EW-16 M1vKTWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnHaTWM2OD1zLkiyPFc2KM7:TR?= M2TZ[3NCVkeHUh?=
SK-NEP-1 NEnRWGdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXrJR|UxRTFwOE[5PFgh|ryP MUfTRW5ITVJ?
NCI-H226 NF:5NHZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NY\BSVhLUUN3ME2xMlg6OzV7IN88US=> MWnTRW5ITVJ?
HOP-92 NF3GZo5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NELmbVZKSzVyPUGuPVYxQTlizszN NV63e5E4W0GQR1XS
NCI-H441 M1LxOWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4rKbWlEPTB;Mj6wNlM{PyEQvF2= MmDRV2FPT0WU
LU-139 M3jOdmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFvrdoJKSzVyPUKuNFMyOTRizszN NV7uc2pJW0GQR1XS
SJRH30 M4TzeWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUPvRXhqUUN3ME2yMlA1OjV|IN88US=> M13aSHNCVkeHUh?=
MG-63 NFv6S|NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHfWZmdKSzVyPUKuNVQyOTFizszN NYXKTIVUW0GQR1XS
NH-12 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NV\mVmd1UUN3ME2yMlE2ODB4IN88US=> MYTTRW5ITVJ?
NB7 MXjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M17l[mlEPTB;Mj6xPVY4OyEQvF2= NFy3blRUSU6JRWK=
LB771-HNC MlfRS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFfWc|RKSzVyPUKuNlA2QTVizszN MWHTRW5ITVJ?
HCC1569 Mn[xS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXPJR|UxRTJwMkS1PFMh|ryP M2rxc3NCVkeHUh?=
D-283MED NVy2W4xLT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEW5b2VKSzVyPUKuNlQ4QDJizszN M1rJSXNCVkeHUh?=
J-RT3-T3-5 MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3vZdmlEPTB;Mj6yOVM2OSEQvF2= MY\TRW5ITVJ?
ATN-1 Ml[0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGP3T2pKSzVyPUKuN|MxQDJizszN Mnn0V2FPT0WU
HCC1954 M4OwOWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHrxXGVKSzVyPUKuN|Q1ODhizszN MXjTRW5ITVJ?
SCC-15 MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVHQOW1FUUN3ME2yMlM6OzF{IN88US=> MWfTRW5ITVJ?
COLO-668 M2nXXmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1j4ZWlEPTB;Mj60N|Ih|ryP MU\TRW5ITVJ?
LB373-MEL-D MnW2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoPWTWM2OD1{LkW0Olc4KM7:TR?= NVTK[GtPW0GQR1XS
no-10 MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWTJR|UxRTJwNUS5OFch|ryP M1nVVnNCVkeHUh?=
HT-1197 MUHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWrie3VCUUN3ME2yMlY{OTh6IN88US=> MVTTRW5ITVJ?
DU-145 M1fOcWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoWwTWM2OD1{Lke5NVYzKM7:TR?= NID5V4tUSU6JRWK=
SK-N-AS M4PyZmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NH33XYVKSzVyPUKuPFQ3QTJizszN M1uzd3NCVkeHUh?=
MOLT-4 MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4\vcWlEPTB;Mj64OVMzOiEQvF2= MXvTRW5ITVJ?
EW-22 M{frVGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYez[3Z1UUN3ME2yMlkzQDRzIN88US=> MVnTRW5ITVJ?
DB NH;1NmFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmH5TWM2OD1{Lkm3O|U6KM7:TR?= NV3URXR2W0GQR1XS
HL-60 MWnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1u2NWlEPTB;Mz6wOFM4PiEQvF2= NFrwRVNUSU6JRWK=
SK-N-DZ NXLwe3A{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmnjTWM2OD1|LkC1NFc2KM7:TR?= NFrlRW1USU6JRWK=
NY MmLWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnPsTWM2OD1|LkC4OVQzKM7:TR?= M2\qeXNCVkeHUh?=
T47D M2HT[2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUnVPIJIUUN3ME2zMlExPTV6IN88US=> NXPuXVJlW0GQR1XS
NCI-H2029 NGnI[oxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{nSR2lEPTB;Mz6yNlQ4PyEQvF2= M4i4RXNCVkeHUh?=
KARPAS-299 M{PCdGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVW1emJSUUN3ME2zMlI3ODJ5IN88US=> MYPTRW5ITVJ?
KM-H2 NVHpXGJnT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVzJR|UxRTNwM{C2PEDPxE1? M3rEUnNCVkeHUh?=
CHP-134 M4HXcGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFH1UHFKSzVyPUOuOFc{QSEQvF2= MUXTRW5ITVJ?
22RV1 NWK0e2lIT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWXJR|UxRTNwNEmxOlgh|ryP M{jGPXNCVkeHUh?=
NB5 NVfqOWEyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWrnemZHUUN3ME2zMlUxPjh7IN88US=> MYPTRW5ITVJ?
CW-2 NFHRb5JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NI\4ZVlKSzVyPUOuOVU{OTRizszN NEPwPXVUSU6JRWK=
EFO-21 M{OxTGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmfFTWM2OD1|LkW2PVQh|ryP NFPFb4NUSU6JRWK=
HuH-7 MkfVS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NE\QcZZKSzVyPUOuOVg1OTRizszN MW\TRW5ITVJ?
ALL-PO NYDZSo93T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2ezUmlEPTB;Mz62NlM{PSEQvF2= MXfTRW5ITVJ?
EM-2 NF3NbXNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFjh[ZRKSzVyPUOuOlkxOTFizszN NWHzVIxTW0GQR1XS
KLE MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUDJR|UxRTNwN{OwNlkh|ryP MoW0V2FPT0WU
NEC8 MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NW\mV5N5UUN3ME2zMlkyQDB6IN88US=> M4PEU3NCVkeHUh?=
KP-N-YN M2H0bmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MY\JR|UxRTNwOUO0O|Yh|ryP MmG0V2FPT0WU
SK-MEL-1 MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVfJR|UxRTRwMEO1NVgh|ryP NGXqZnZUSU6JRWK=
CAL-54 MnmxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2\XVmlEPTB;ND6wOVkyKM7:TR?= Mn7VV2FPT0WU
MS-1 NFzUeVlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlqzTWM2OD12LkG2NVU2KM7:TR?= NFSxRZZUSU6JRWK=
NCI-H209 MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGHIUplKSzVyPUSuNlk6QTlizszN M{\zNXNCVkeHUh?=
NOMO-1 M1n4VWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFvGdpBKSzVyPUSuN|IyOzFizszN NFyxNG1USU6JRWK=
RPMI-2650 MkPqS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFi3eZNKSzVyPUSuN|Y{OjdizszN Mn7JV2FPT0WU
NCI-H810 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEjjWoNKSzVyPUSuN|k4OzZizszN NWHjUHEzW0GQR1XS
Ca9-22 NFvGTJhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYfUclBZUUN3ME20MlQ2PjlzIN88US=> M3TqZXNCVkeHUh?=
ES4 NHXsVpZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnX0TWM2OD12LkS3NFk2KM7:TR?= M3;OSHNCVkeHUh?=
ES6 M33LNWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NF7j[YJKSzVyPUSuOFk3PTdizszN MkLNV2FPT0WU
DMS-114 MoTGS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2nDS2lEPTB;ND61OFY6OSEQvF2= MWDTRW5ITVJ?
ONS-76 MoTXS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXHGdVQzUUN3ME20MlU4QTVizszN M3y0UnNCVkeHUh?=
K-562 Mki2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGjBd5VKSzVyPUSuO|M5OTRizszN NImyVnhUSU6JRWK=
MHH-NB-11 M{XVXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{nlZ2lEPTB;ND63OVQ3OSEQvF2= NUj5VGhmW0GQR1XS
Calu-3 NVnwOXlmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlO5TWM2OD12Lke4OVQ5KM7:TR?= MWPTRW5ITVJ?
HT55 NIHuZ4xIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGLTOnlKSzVyPUSuPFQ2PDVizszN MmHmV2FPT0WU
SK-N-FI NHXSfYxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYnJR|UxRTRwOEWwNFkh|ryP MV;TRW5ITVJ?
ES1 NEXrOXVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mk\wTWM2OD12Lki2NFU4KM7:TR?= NF\xZ5JUSU6JRWK=
SF126 NFrwWGpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUXJR|UxRTRwOUOxPFQh|ryP MX7TRW5ITVJ?
ES5 M2L6Umdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MV7JR|UxRTVwMUK0Nlch|ryP MXTTRW5ITVJ?
LoVo MorES5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUjJR|UxRTVwMUW4O|Eh|ryP MUjTRW5ITVJ?
SNU-387 NWP4TIdkT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1HKOmlEPTB;NT6zNlM{QSEQvF2= M3LNUHNCVkeHUh?=
C8166 Mk\xS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHjyRnVKSzVyPUWuN|Y{OzlizszN NYe1V5FZW0GQR1XS
LS-1034 NWW4SIN1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVTJR|UxRTVwNEKzNFch|ryP MVXTRW5ITVJ?
GR-ST NXr5eXdnT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NY\WSpJrUUN3ME21MlUzOjBzIN88US=> NIjrZnlUSU6JRWK=
NCI-H1092 M1z2T2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4TEOWlEPTB;NT63Nlg1OyEQvF2= NYLVW4t5W0GQR1XS
647-V MoroS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NULiUnpwUUN3ME21Mlc1PzB4IN88US=> Mmr4V2FPT0WU
EW-13 M3n0VGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXvmcVVwUUN3ME21Mlc3PjJ5IN88US=> NH;MV45USU6JRWK=
KGN MkDBS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NID4OWRKSzVyPU[uNFk6OjFizszN MnWwV2FPT0WU
D-423MG M1jZZ2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4DJZWlEPTB;Nj60NFI5PCEQvF2= NW\NToE3W0GQR1XS
ECC10 M4DycWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYPJR|UxRTdwMUCxNFEh|ryP MmP5V2FPT0WU
TE-5 MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFLKfI9KSzVyPUeuOFEzQThizszN M{KyTHNCVkeHUh?=
P12-ICHIKAWA Mn;pS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1O3R2lEPTB;Nz60OVUzOyEQvF2= M174S3NCVkeHUh?=
NCI-H82 M{PuZmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoTnTWM2OD15LkS1O|AyKM7:TR?= NWfZTFN[W0GQR1XS
NCI-H1993 M4\HTWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYXJR|UxRTdwOEOwOlMh|ryP MmnCV2FPT0WU
RH-1 NF[5bZVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mn3LTWM2OD15Lki1NlQ1KM7:TR?= M3K3eHNCVkeHUh?=
SW948 M37ufmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mkj2TWM2OD15Lkm2NFQ6KM7:TR?= NEDad21USU6JRWK=
CAL-33 NGnjTVVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{K5NmlEPTB;Nz65PVk{QCEQvF2= MXLTRW5ITVJ?
U-266 MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYnJR|UxRThwMUW3O|ch|ryP NFHiOHJUSU6JRWK=
CAL-72 NEHiPVlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXv2eY06UUN3ME24MlIxOzJizszN Ml\JV2FPT0WU
SNU-423 MoDZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUTJR|UxRTlwM{[2OlYh|ryP MYXTRW5ITVJ?
KG-1 NFLrcphIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnnCTWM2OD17LkW4OFU3KM7:TR?= M1fTcXNCVkeHUh?=
HCC1395 MkTIS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1vmV2lEPTB;OT65NlM2OiEQvF2= M4npPXNCVkeHUh?=
BE-13 MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWXRUW1nUUN3ME2xNE45QDl{IN88US=> NF7qd3pUSU6JRWK=
MKN7 MVHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVLJeolEUUN3ME2xNE46PzZ3IN88US=> MlnHV2FPT0WU
697 M{LsOGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3XK[mlEPTB;MUGuNVQ4OiEQvF2= NWnnWXRvW0GQR1XS
LU-135 NXG2OZlmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnvXTWM2OD1zMT6yN|A4KM7:TR?= M4XDSnNCVkeHUh?=
ES7 NV;ZVHltT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYrKXVZyUUN3ME2xNU4{OzF|IN88US=> MoO1V2FPT0WU
SK-HEP-1 M164XWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MX3JR|UxRTFzLke2OFYh|ryP NXHTVGJMW0GQR1XS
BEN MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MX3JR|UxRTFzLki1NUDPxE1? MmHhV2FPT0WU
NCI-H1770 NHnrc5RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWLpTYZJUUN3ME2xNk4yOjZizszN M3XITHNCVkeHUh?=
SW13 NHy2WIRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWTJR|UxRTF{LkG1OFEh|ryP NWrVTYg6W0GQR1XS
MZ1-PC NXHTbopDT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUnJR|UxRTF{LkW0OVIh|ryP MlrwV2FPT0WU
Mo-T Ml:3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXX3fWJ[UUN3ME2xNk44PDJzIN88US=> NXS0VXZSW0GQR1XS
HLE MnfxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHHJ[JRKSzVyPUGyMlgzOTVizszN NHzl[3hUSU6JRWK=
RCC10RGB MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mn3CTWM2OD1zMz62O|Eh|ryP M{\ESHNCVkeHUh?=
COLO-320-HSR NFP4XphIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYDJR|UxRTF|LkezPFEh|ryP NUexeHQzW0GQR1XS
BHT-101 MorKS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGjJTVJKSzVyPUGzMlg{PDVizszN MWnTRW5ITVJ?
OCUB-M NGf1PZVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1zDdGlEPTB;MUSuNVYxOiEQvF2= NFTDOFJUSU6JRWK=
MEG-01 NETOcVhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXv6R4J2UUN3ME2xOE4{PzB6IN88US=> MojHV2FPT0WU
RS4-11 NXTiUpFyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUDRRWxNUUN3ME2xOE44PDJizszN Mn\HV2FPT0WU
MN-60 MkjVS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NULxWXNkUUN3ME2xOE44QDl2IN88US=> NUHReHo2W0GQR1XS
NCI-H1304 MVTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NF;VUGpKSzVyPUG1MlA1OjVizszN NGq5W|ZUSU6JRWK=
Ramos-2G6-4C10 MojKS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXHJR|UxRTF3LkC1PFEh|ryP M1ryWXNCVkeHUh?=
NCI-H2342 NUX0cFNTT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2HDfWlEPTB;MUWuNlA1PCEQvF2= MVXTRW5ITVJ?
LAN-6 MYjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVjJR|UxRTF3LkS0NVQh|ryP NWr1VWlzW0GQR1XS
JVM-2 Mn;hS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NES4UHpKSzVyPUG1MlU4PDhizszN MoexV2FPT0WU
P30-OHK NV7qVZdxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGC4eZRKSzVyPUG2MlA3OTRizszN MojGV2FPT0WU
C-33-A NXHqUVQxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWH5VFN6UUN3ME2xOk43OjF2IN88US=> MnvaV2FPT0WU
RPMI-8866 M2LjT2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHq1PJJKSzVyPUG2Mlg1QTZizszN M1LsOXNCVkeHUh?=
NCI-H630 M1TBT2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWrrWpZlUUN3ME2xOk45PTN5IN88US=> MXjTRW5ITVJ?
KYSE-140 NH35O5FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mn\STWM2OD1zNz6yNFI5KM7:TR?= MmHyV2FPT0WU
T84 NWPNfml6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEXxboRKSzVyPUG4Mlg3QTVizszN MknEV2FPT0WU
KU-19-19 MkLmS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVftcYpDUUN3ME2xPE46PjB6IN88US=> NHHWOlFUSU6JRWK=
BALL-1 NXTSXZJMT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoPTTWM2OD1zOT6zN|k6KM7:TR?= MXHTRW5ITVJ?
Calu-6 NX7ST|R6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFfEZmhKSzVyPUG5MlQ6OiEQvF2= NETLTYNUSU6JRWK=
EGI-1 NGLlTXpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFLkXVdKSzVyPUG5MlU6QCEQvF2= MXHTRW5ITVJ?
MFH-ino MnqyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MULJR|UxRTF7Lke0OVQh|ryP NIOzVI5USU6JRWK=
GB-1 NHfZVHNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXzJR|UxRTJyLkO1N|Uh|ryP MonxV2FPT0WU
NCI-H1693 M33NRmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWHJR|UxRTJyLk[1NFUh|ryP M{KwWXNCVkeHUh?=
SW1116 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVvIUmhlUUN3ME2yNE46OzZ{IN88US=> MXzTRW5ITVJ?
H-EMC-SS M2X6T2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWjoXVh3UUN3ME2yNk4xPDVizszN MmfSV2FPT0WU
D-502MG NVz2[Wd[T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlvRTWM2OD1{Mj64NlYyKM7:TR?= Mm[5V2FPT0WU
IA-LM NGHLXlVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlvzTWM2OD1{Mz6yOFk{KM7:TR?= MlvaV2FPT0WU
SW1463 M3\QSGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWnJR|UxRTJ|Lke5JO69VQ>? NYXMOolNW0GQR1XS
JAR MomyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MV7JR|UxRTJ2LkOyPVMh|ryP MV\TRW5ITVJ?
HT NGXlfGVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYXJR|UxRTJ2LkS3OVMh|ryP NVnXRZVDW0GQR1XS
LCLC-103H NFTvPIdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIH1dZJKSzVyPUK0Mlg1PDlizszN NVvVWHNSW0GQR1XS
SNU-449 Mn;0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NED1NYVKSzVyPUK0Mlg4PDFizszN NFS4SXNUSU6JRWK=
KE-37 M4\OT2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGT0dVJKSzVyPUK1MlA6OjhizszN MmjjV2FPT0WU
NCI-H1623 MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3nvbmlEPTB;MkeuNVMxOyEQvF2= MknoV2FPT0WU
MOLT-13 NWXmbnVPT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVrId2lyUUN3ME2yO{4{PTF4IN88US=> NXrxfIdEW0GQR1XS
COLO-741 MoDlS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXPmcmQ4UUN3ME2zNU4{OzN|IN88US=> MVjTRW5ITVJ?
NB6 NWj2bYw6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoHuTWM2OD1|Mj6yPFc3KM7:TR?= NYSy[2lVW0GQR1XS
MOLT-16 NWHlcFRGT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXH1Z3N5UUN3ME2zN{4xODV3IN88US=> NFm1VVhUSU6JRWK=
IST-MES1 MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFnJcGxKSzVyPUO0MlA2PDFizszN MoXNV2FPT0WU
A4-Fuk MnfZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NV;TPXFZUUN3ME2zOU4xPjZizszN NIqzb5ZUSU6JRWK=
CAL-85-1 M4DPW2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnHUTWM2OD1|NT6yPFE4KM7:TR?= NYDMNm51W0GQR1XS
CCRF-CEM NWXWUINtT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mk\4TWM2OD1|Nz6xOVM3KM7:TR?= Mlr0V2FPT0WU
HAL-01 NUDkTmtLT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUfMdI5tUUN3ME2zPE41QDh7IN88US=> NFHKcoRUSU6JRWK=
HEL NHOzZZVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mo[2TWM2OD12Mz6zOFA6KM7:TR?= NHG5bmJUSU6JRWK=
EW-1 NXHrfHlkT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYTmeFFSUUN3ME20N{41PzZ6IN88US=> M37S[XNCVkeHUh?=
MDA-MB-231 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUewZ25jUUN3ME20OU4yOTl7IN88US=> MWLTRW5ITVJ?
ABC-1 NETiOYRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NH;OfYlKSzVyPUS2Mlg2OzhizszN M133OXNCVkeHUh?=
NCI-H446 NEfJdYRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NF;6[mNKSzVyPUS4MlUxPThizszN MVfTRW5ITVJ?
MHH-PREB-1 MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYDHcGZFUUN3ME20PU43ODB5IN88US=> NH;HfmJUSU6JRWK=
DOHH-2 MnS2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGq2eYlKSzVyPUS5MlY3PTZizszN NVr3XIVrW0GQR1XS
GCT NIjGd4RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEn4SYVKSzVyPUS5MlY6PzZizszN NWjTbI5zW0GQR1XS

... Click to View More Cell Line Experimental Data

In vivo試験 17-AAG displays significantly higher binding affinity for Hsp90 from 3T3-src, B16 or CT26 xenografts in nude mice with IC50 values of 8-35 nM as compared with that from the normal tissues with IC50 values of 200-600 nM. [1] Administration of 17-AAG (~50 mg/kg) causes significant decline in AR, HER2, HER3, and Akt expression in a dose-dependent manner with >50% decline at dose of 50 mg/kg, resulting in the dose-dependent inhibition of androgen-dependent (CWR22) and -independent (CWR22R and CWRSA6) prostate cancer xenografts growth by 67%, 80% and 68% at dose of 50 mg/kg, respectively. [2]
臨床試験 A Phase II study of 17-AAG in patients with relapsed/refractory CD30 plus anaplastic large cell lymphoma (ALCL) relapsed/refractory mantle cell lymphoma (MCL) and relapsed/refractory classical Hodgkin's lymphoma (HL) has been completed.
特集 Displays very low toxicity toward normal cells.

プロトコル (参考用のみ)

キナーゼアッセイ: [1]

Hsp90 binding assays Purified native Hsp90 protein or cell lysates from HER-2-overexpressing cancer cells (BT474, N87, SKOV3 and SKBR3) or BT474 breast carcinoma cells in lysis buffer (20 mM HEPES, pH 7.3, 1 mM EDTA, 5 mM MgCl2, 100 mM KCl) are incubated with various concentrations of 17-AAG for 30 minutes at 4 °C, and then incubated with biotin-GM linked to BioMag streptavidin magnetic beads for 1 hour at 4 °C. Tubes are placed on a magnetic rack, and the unbound supernatant removed. The magnetic beads are washed three times in lysis buffer and heated for 5 minutes at 95 °C in SDS–PAGE sample buffer. Samples are analysed on SDS protein gels, and western blots done using indicated antibodies. Bands in the western blots are quantified using the Bio-rad Fluor-S MultiImager, and the percentage inhibition of binding of Hsp90 to the biotin-GM is calculated. The IC50 reported is the concentration of 17-AAG needed to cause half-maximal inhibition of binding.

細胞アッセイ: [1]

細胞株 BT474, SKBR3, N87, SKOV3, MCF7, MDA468, Hs578T, Hs578Bst, A549, HT29, U87, SKMG3, HT1080, RPTEC, NDF, HMVEC, HMEC, HUVEC, and PBMC cells
濃度 Dissolved in DMSO, final concentrations ~10 μM
反応時間 5 days
実験の流れ Cells are seeded in 96-well plates at 2,000 cells per well in a final culture volume of 100 μL for 24 hours before the addition of increasing concentrations of 17-AAG that is incubated for 5 days. Viable cell number is determined using the Celltiter 96 AQueous Nonradioactive Cell Proliferation Assay. The value of the background absorbance at 490 nm (A490) of wells not containing cells is subtracted. Percentage of viable cells = (A490 of 17-AAG treated sample/A490 untreated cells) × 100. The IC50 is defined as the concentration that gave rise to 50% viable cell number.

動物実験: [2]

動物モデル Male nu/nu athymic mice inoculated s.c. with androgen-dependent CWR22 xenograft, and female nu/nu athymic mice inoculated s.c. with androgen-independent xenografts CWR22R and CWRSA6
製剤 Dissolved in DMSO, and diluted in egg phospholipids (EPL) vehicle
投薬量 ~50 mg/kg
投与方法 Injection i.p.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)

SpeciesMouseRatRabbitGuinea pigHamsterDogMonkeyBaboon
Weight (kg)0.020.151.80.40.0810312
Body Surface Area (m2)0.0070.0250.150.050.020.50.240.6
Km factor361285201220
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Rat dose (mg/kg) = mouse dose (22.4 mg/kg) ×  mouse Km(3)  = 11.2 mg/kg
rat Km(6)
1

参考

化学情報

Download 17-AAG (Tanespimycin) SDF
分子量 585.69
化学式

C31H43N3O8

CAS No. 75747-14-7
保管 3年-20℃
2年-80℃in solvent
別名 CP127374,NSC-330507, KOS 953
溶解度 (25°C) * In vitro DMSO 100 mg/mL (170.73 mM)
Ethanol 5 mg/mL (8.53 mM)
Water <1 mg/mL
In vivo 5%DMSO+corn oil 10mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
化学名 17-demethoxy-17-(2-propenylamino)- [(3R,5R,6S,7R,8E,10R,11R,12Z,14E)-6-Hydroxy-5,11,21-trimethoxy-3,7,9,15-tetramethyl-16,20,22-trioxo-17-azabicyclo[16.3.1]docosa-1(21),8,12,14,18-pentaen-10-yl] carbamate

文献中の引用 (19)

Frequently Asked Questions

  • Question 1
    What kind of subtypes does this compound inhibit? HSP90α or HSP90β ?

    Answer: 17-AAG can inhibit both HSP90α and HSP90β, but it is unclear how much are they affected respectively. You should note that Hsp90 derived from tumor cells has a 100-fold higher binding affinity for 17-AAG than that from normal cells according to this paper. http://www.nature.com.ezp-prod1.hul.harvard.edu/nature/journal/v425/n6956/full/nature01913.html

技術サポート&よくある質問(FAQ)

ストックの作り方、阻害剤の保管する方法、細胞実験や動物実験に注意すべきな点を全部含めており、製品を取扱う時よくあった質問に対して取扱説明書でお答えいたします。

電話番号: +1-832-582-8158 Ext:3月曜日〜金曜日 9:00 AM–5:00 PM (米国中部標準時)

他の質問がある場合は、お気軽くお問合せください。

* 必須

Related HSP (e.g. HSP90) 阻害剤

  • PU-H71

    PU-H71 is a potent and selective inhibitor of HSP90 with IC50 of 51 nM.

  • KNK437

    KNK437は1種のパン(pan)- HSP 阻害剤で、誘導HSPsの合成(HSP105、 HSP72,と HSP40を含める)を抑制します。

  • VER155008

    VER-155008 is a potent Hsp70 family inhibitor with IC50 of 0.5 μM, 2.6 μM, and 2.6 μM in cell-free assays for HSP70, HSC70, and GRP78, respectively, >100-fold selectivity over HSP90.

  • FRAX597

    FRAX597 is a potent, ATP-competitive inhibitor of group I PAKs with IC50 of 8 nM, 13 nM, and 19 nM for PAK1, PAK2, and PAK3, respectively.

  • Luminespib (AUY-922, NVP-AUY922)

    Luminespib (AUY-922, NVP-AUY922)は高度的に HSP90 を抑制、 HSP90α と HSP90β を作用すると、 IC50 がそれぞれ 13 nM 、 21 nM となる。

  • Ganetespib (STA-9090)

    Ganetespib (STA-9090)は独特な triazolone-containing Hsp90阻害剤、 IC50 が4 nM となる.

  • 17-DMAG (Alvespimycin) HCl

    17-DMAG (Alvespimycin) HClは、62nMのIC50による強力なHsp90阻害剤です。

    Features:A synthetic derivative Geldanamycin, with lower hepatotoxicity than parent antibiotic & higher potency and bioavailability than the similar derivative 17-AAG.

  • Geldanamycin

    Geldanamycinは一種の天然なHSP90阻害剤で、Kd値が1.2μMですが、糖質ステロイド受容体(GR)/HSP連合を特異性的に妨害します。

  • HSP990 (NVP-HSP990)

    NVP-HSP990 (HSP990) is a novel, potent and selective HSP90 inhibitor for HSP90α/β with IC50 of 0.6 nM/0.8 nM.

    Features:NVP-HSP990 is an orally available HSP90 inhibitor and is structurally distinct from other clinical HSP90 inhibitors.

最近チェックしたアイテム

Tags: 17-AAG (Tanespimycin)を買う | 17-AAG (Tanespimycin)供給者 | 17-AAG (Tanespimycin)を購入する | 17-AAG (Tanespimycin)費用 | 17-AAG (Tanespimycin)生産者 | オーダー17-AAG (Tanespimycin) | 17-AAG (Tanespimycin)代理店
×
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
お問い合わせ