Tanespimycin (17-AAG) 化学構造
分子量: 585.69

高品質保証

カスタマーフィードバック(7)

MSDS

製品説明

  • Compare HSP (e.g. HSP90) Inhibitors
    HSP (e.g. HSP90)製品生物活性の比較
  • 研究分野

製品の説明

生物活性

製品説明 Tanespimycin (17-AAG)は、5nMのIC50による強力な熱ショックタンパク質90(Hsp90)阻害剤です。
ターゲット HSP90
IC50 5 nM [1]
In vitro試験 17-AAG, an analog of geldanamycin, exhibits greater than 100 times higher binding affinity for Hsp90 derived from HER-2-overexpressing cancer cells (BT474, N87, SKOV3 and SKBR3) or BT474 breast carcinoma cells with IC50 values of 5-6 nM. [1] 17-AAG causes the degradation of HER2, HER3, Akt, and both mutant and wild-type androgen receptor (AR), leading to the RB-dependent G1 growth arrest of prostate cancer cells such as LNCaP, LAPC-4, DU-145, and PC-3 with IC50 values of 25-45 nM. [2] In addition to inducing apoptosis of Ba/F3 cells transformed with wild-type BCR-ABL with an IC50 of 5.2 μM, 17-AAG has the ability to induce apoptosis of cells transformed with imatinib mesylate-resistant T315I and E255K BCR-ABL mutants with IC50 values of 2.3 μM and 1.0 μM, respectively, by inducing the degradation of both wild-type BCR-ABL protein and mutants. [3]
Cell Data
Cell LinesAssay TypeConcentrationIncubation TimeFormulationActivity DescriptionPMID
A549 M2O0dGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUXJR|UxRTBwMECwN|A{KM7:TR?= MVXTRW5ITVJ?
IST-MEL1 M3npT2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYrJR|UxRTBwMECwOFA4KM7:TR?= NXvGS3dQW0GQR1XS
NCI-SNU-1 MUHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MX;JR|UxRTBwMECyNFch|ryP NWezVZJbW0GQR1XS
FADU Mn7BS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2fub2lEPTB;MD6wNFIxQSEQvF2= MYrTRW5ITVJ?
C32 NHXuXGVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4jB[GlEPTB;MD6wNFMxPCEQvF2= MXLTRW5ITVJ?
D-566MG M2Psdmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWnTfHJRUUN3ME2wMlAxOzlizszN NV;2dWZ7W0GQR1XS
LXF-289 M4nzeWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MX3JR|UxRTBwMEC0NVkh|ryP M4LQXHNCVkeHUh?=
HGC-27 NIjYelNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYe0ZplyUUN3ME2wMlAxPTFizszN NYeyfWZRW0GQR1XS
RPMI-7951 MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mn7WTWM2OD1yLkCwO|E4KM7:TR?= M4nw[3NCVkeHUh?=
HSC-3 MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHjDd5BKSzVyPUCuNFA6OjlizszN NYDyelhiW0GQR1XS
MIA-PaCa-2 MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NG\NVXVKSzVyPUCuNFExODlizszN MVXTRW5ITVJ?
KS-1 Mkf0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4jKfmlEPTB;MD6wNVM2PSEQvF2= NFfYPWVUSU6JRWK=
CAL-51 MYjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoLOTWM2OD1yLkCxOFA2KM7:TR?= MWLTRW5ITVJ?
MDA-MB-361 NGTKZlRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlrFTWM2OD1yLkCxOFk2KM7:TR?= Mnq2V2FPT0WU
TI-73 NImyeIhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3LJUWlEPTB;MD6wNVc6PiEQvF2= M4HLXXNCVkeHUh?=
AGS MoH0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NF7Z[mVKSzVyPUCuNFE6OzhizszN Mn7zV2FPT0WU
NCI-H460 M3nY[Gdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXjJR|UxRTBwMEG5O|Qh|ryP MXjTRW5ITVJ?
A204 NH;wVWxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVLJR|UxRTBwMEKyOFkh|ryP NISyWVhUSU6JRWK=
CHL-1 MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEP1UHRKSzVyPUCuNFIzPTFizszN MYjTRW5ITVJ?
DU-4475 M3j3b2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmiyTWM2OD1yLkCyNlYyKM7:TR?= M1mxd3NCVkeHUh?=
CGTH-W-1 M1LSRWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHfNUW5KSzVyPUCuNFI{PDlizszN M4fteHNCVkeHUh?=
HCC2218 MXTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NI\mNFdKSzVyPUCuNFI1QTRizszN Mn[zV2FPT0WU
A2780 M2\hTmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXrJR|UxRTBwMEK1N|Eh|ryP NV7We2pYW0GQR1XS
NCI-H720 MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUDJR|UxRTBwMEK1OFYh|ryP M4LZenNCVkeHUh?=
NCI-N87 MkCyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVTJR|UxRTBwMEK1PVMh|ryP NF7hN2hUSU6JRWK=
CHP-212 NIDoNJRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{nKNWlEPTB;MD6wNlYzQCEQvF2= NEfHVnZUSU6JRWK=
NCI-H23 NGDqd4hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MW\JR|UxRTBwMEK2OlUh|ryP M3zMWnNCVkeHUh?=
D-263MG NXGxRoQyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVfY[HpQUUN3ME2wMlAzPzh4IN88US=> MW\TRW5ITVJ?
ME-180 MkHsS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnHwTWM2OD1yLkCyPFkyKM7:TR?= MUjTRW5ITVJ?
SW982 NXe1OlJ5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{K3XWlEPTB;MD6wNlk6QSEQvF2= MnvrV2FPT0WU
OE19 NXnqfGdPT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUXJR|UxRTBwMEOwO|ch|ryP MkCxV2FPT0WU
SK-LU-1 M2DaTWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFf3Z2FKSzVyPUCuNFMxQDJizszN M4[xPHNCVkeHUh?=
H4 M37KZmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWHJR|UxRTBwMEOwPUDPxE1? MV\TRW5ITVJ?
HT-144 NGTqNndIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mmr0TWM2OD1yLkCzNFk{KM7:TR?= NWfLdolCW0GQR1XS
SK-UT-1 MmD5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGrv[mhKSzVyPUCuNFMyPzhizszN NHzH[ZNUSU6JRWK=
D-336MG NYL2d5lXT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3HrbGlEPTB;MD6wN|MxQSEQvF2= NXzTdoFOW0GQR1XS
MDA-MB-175-VII M3;jOWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3zafWlEPTB;MD6wN|M2PCEQvF2= MVnTRW5ITVJ?
GAMG M1fINmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1[xfGlEPTB;MD6wN|Q{PSEQvF2= NWe5TopWW0GQR1XS
CP50-MEL-B NY[0[JRIT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mm\ZTWM2OD1yLkCzOFUh|ryP Ml3DV2FPT0WU
OVCAR-5 MX3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2XCbGlEPTB;MD6wN|Q5KM7:TR?= NWj5cm1pW0GQR1XS
SK-MES-1 NYrrZ3YyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkXGTWM2OD1yLkCzOlA3KM7:TR?= MX\TRW5ITVJ?
VM-CUB-1 M{\GN2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2fnVWlEPTB;MD6wN|Y2PyEQvF2= MULTRW5ITVJ?
WM-115 MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3XsZ2lEPTB;MD6wN|c3OiEQvF2= MUnTRW5ITVJ?
DSH1 MoTLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWDJR|UxRTBwMEO4NFch|ryP M2nYfHNCVkeHUh?=
Becker NGO2bm9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NH3vcGtKSzVyPUCuNFM5QDVizszN NYTpSYJxW0GQR1XS
SW962 M{Ppd2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmD5TWM2OD1yLkCzPVQ2KM7:TR?= M1fP[nNCVkeHUh?=
TYK-nu NIXLfYpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFXXU4RKSzVyPUCuNFM6QDVizszN MXXTRW5ITVJ?
HO-1-N-1 NHToXoxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEHNfHVKSzVyPUCuNFQxOjFizszN NIjrN3ZUSU6JRWK=
T98G Moj6S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXT2c3huUUN3ME2wMlA1OTB|IN88US=> MWDTRW5ITVJ?
ACN NHq2[2NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYfJR|UxRTBwMESxOlIh|ryP M{nPd3NCVkeHUh?=
SW780 MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4Lt[mlEPTB;MD6wOFIxOyEQvF2= MlvZV2FPT0WU
Detroit562 M1XFc2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUnt[Fd{UUN3ME2wMlA1OjN7IN88US=> NFfSfHRUSU6JRWK=
BB49-HNC M{D5VWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkKwTWM2OD1yLkC0NlQ{KM7:TR?= NEfLcFVUSU6JRWK=
HN NYrPS2h5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4DwZ2lEPTB;MD6wOFI4OiEQvF2= Mkn4V2FPT0WU
H9 NWnH[WRRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmPiTWM2OD1yLkC0N|cyKM7:TR?= MVrTRW5ITVJ?
VA-ES-BJ NHfXdI9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NE\jcZVKSzVyPUCuNFQ1PDdizszN MYPTRW5ITVJ?
MEL-JUSO NGTQeoVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mkn6TWM2OD1yLkC0OFc2KM7:TR?= MoLSV2FPT0WU
BT-474 MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoXVTWM2OD1yLkC0OUDPxE1? M4\me3NCVkeHUh?=
CaR-1 NHPkOI1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGLIeXhKSzVyPUCuNFQ2PDlizszN MV7TRW5ITVJ?
PSN1 MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{L4OWlEPTB;MD6wOFYxOyEQvF2= M1HsWnNCVkeHUh?=
KYSE-510 NWfr[G1yT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYHJR|UxRTBwMES2OFkh|ryP MlK2V2FPT0WU
KP-4 NF3VVYtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEnlTZRKSzVyPUCuNFQ4PTNizszN MluyV2FPT0WU
KYSE-410 MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmLCTWM2OD1yLkC0O|czKM7:TR?= MWHTRW5ITVJ?
G-402 MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVrJR|UxRTBwMES3PFkh|ryP MXvTRW5ITVJ?
DOK MlPkS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MojBTWM2OD1yLkC0PVAzKM7:TR?= Mn;vV2FPT0WU
COR-L88 M1rub2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NITRXXpKSzVyPUCuNFQ6OTJizszN NV7neY1lW0GQR1XS
SKG-IIIa M{Lr[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWnJVIQ2UUN3ME2wMlA1QTh4IN88US=> MXvTRW5ITVJ?
AN3-CA M1z3UWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXrTO|hYUUN3ME2wMlA2KM7:TR?= NFTjNVdUSU6JRWK=
SW48 NXXGSoxKT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVTJR|UxRTBwMEWwN|kh|ryP M{jIU3NCVkeHUh?=
YKG-1 M1jsU2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWDJR|UxRTBwMEWwO|Eh|ryP MlziV2FPT0WU
KYSE-150 MlfES5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVvJR|UxRTBwMEWyN|Uh|ryP MVvTRW5ITVJ?
HuO-3N1 NGPrWYdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYXiWmt3UUN3ME2wMlA2OjN5IN88US=> NFvMTFBUSU6JRWK=
LB1047-RCC MmXOS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYrHVmVrUUN3ME2wMlA2Ojl4IN88US=> M3zxfHNCVkeHUh?=
NCI-H2030 NIXR[mpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGDUNFVKSzVyPUCuNFU1OTRizszN M4PCZnNCVkeHUh?=
YH-13 NWXV[4xxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXvJR|UxRTBwMEW3NlIh|ryP MlyyV2FPT0WU
5637 NGL5blNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NW\TZ41pUUN3ME2wMlA2PzRizszN MUnTRW5ITVJ?
LOXIMVI M{jON2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHLib3FKSzVyPUCuNFU5PzJizszN NHjQOpBUSU6JRWK=
GT3TKB MnrsS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXO1SlN5UUN3ME2wMlA2QTR{IN88US=> NGP6e3dUSU6JRWK=
TCCSUP NEKyRmpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NV;YWpRRUUN3ME2wMlA2QTZ2IN88US=> NHzNfIhUSU6JRWK=
EPLC-272H NUHXdI1DT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVHJR|UxRTBwME[yNFUh|ryP NWjsPWZPW0GQR1XS
LU-99A NF;nW5hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHnLTYhKSzVyPUCuNFYzOzdizszN NWfvOmpLW0GQR1XS
NCI-H1755 MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVj5W|ZQUUN3ME2wMlA3OzRzIN88US=> MVvTRW5ITVJ?
KM12 Mmq2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mkn1TWM2OD1yLkC2N|Q5KM7:TR?= NVzvemI3W0GQR1XS
SF295 MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mn33TWM2OD1yLkC2OFUzKM7:TR?= Mo\BV2FPT0WU
MZ2-MEL M4i2WWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NX\vOmhJUUN3ME2wMlA3PTV|IN88US=> NVXvR5gzW0GQR1XS
HEC-1 MlT3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2KwOGlEPTB;MD6wOlU5QCEQvF2= NELXSm5USU6JRWK=
SW684 NX7YVXoyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{Lzd2lEPTB;MD6wOlU6OSEQvF2= MmfxV2FPT0WU
SF539 MnTqS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mmq2TWM2OD1yLkC2OlgyKM7:TR?= MUnTRW5ITVJ?
GMS-10 NH\VcplIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1W5R2lEPTB;MD6wOlY6QSEQvF2= MoPBV2FPT0WU
MV-4-11 M{XQXmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NX3NXWc1UUN3ME2wMlA3QDB|IN88US=> NVLVeY1HW0GQR1XS
HT-29 NI\iOndIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWLJR|UxRTBwME[5NVkh|ryP MnXvV2FPT0WU
23132-87 Mlz1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnXiTWM2OD1yLkC2PVUh|ryP NYfCfGZrW0GQR1XS
SW620 MULHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3HOV2lEPTB;MD6wO|AzPiEQvF2= NVTONXlYW0GQR1XS
HCC1806 NYW0NWJYT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4niSWlEPTB;MD6wO|E{OSEQvF2= M4jpdnNCVkeHUh?=
Hs-578-T MoGzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHq2bXlKSzVyPUCuNFczODhizszN MnHBV2FPT0WU
A2058 M1z1bGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHjlUlVKSzVyPUCuNFczOjhizszN M1XBVnNCVkeHUh?=
MEL-HO MXzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXfvXXlTUUN3ME2wMlA4OjV3IN88US=> NXKxcHN3W0GQR1XS
HCC2998 Mm\TS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEjEZVZKSzVyPUCuNFc{PDdizszN MUfTRW5ITVJ?
HuO9 MkDLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmTwTWM2OD1yLkC3OVg6KM7:TR?= NIPmVo1USU6JRWK=
CAL-39 NXHkeFVyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NF3KR3pKSzVyPUCuNFc4PjZizszN MULTRW5ITVJ?
M14 NX3MOZBLT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWTRcJA3UUN3ME2wMlA4QTF|IN88US=> NXiyPFIxW0GQR1XS
BFTC-909 M4q2U2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXz4ZoFQUUN3ME2wMlA4QTZ7IN88US=> NF:4doZUSU6JRWK=
TE-11 NWPjZlY{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYXJR|UxRTBwMEe5PVYh|ryP NEjU[YNUSU6JRWK=
TGBC1TKB NIPpTVRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVrOToF6UUN3ME2wMlA5ODR|IN88US=> M1T1dHNCVkeHUh?=
L-363 MmHUS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIm1d3ZKSzVyPUCuNFgzODZizszN M{LGZ3NCVkeHUh?=
A431 M37Ld2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWLjeJdbUUN3ME2wMlA5OjFizszN NF:yeFRUSU6JRWK=
MKN45 NGe2PJdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXfJR|UxRTBwMEiyNVkh|ryP MXLTRW5ITVJ?
HT-1080 M3ryZWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUnJR|UxRTBwMEi0N|kh|ryP Mo\3V2FPT0WU
OVCAR-8 M3\PR2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoX6TWM2OD1yLkC4OlIzKM7:TR?= M3SzcnNCVkeHUh?=
LCLC-97TM1 NFfwb2NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mo\0TWM2OD1yLkC4O|I5KM7:TR?= MkPTV2FPT0WU
M059J Ml3nS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1TBUmlEPTB;MD6wPVAzPyEQvF2= NVvLeW84W0GQR1XS
SK-MEL-2 Mn;vS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUTJR|UxRTBwMEmwOkDPxE1? NWLDUFJzW0GQR1XS
TE-1 M2P0SGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFn5OnZKSzVyPUCuNFkzODRizszN NHPrTYhUSU6JRWK=
KYSE-180 MYPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYn2WJZTUUN3ME2wMlA6OjZ{IN88US=> MVPTRW5ITVJ?
D-247MG M4[3emdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnXMTWM2OD1yLkC5OFU2KM7:TR?= NYjWfYJRW0GQR1XS
8-MG-BA MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVzJR|UxRTBwMEm0O|Ih|ryP M4fSW3NCVkeHUh?=
NCI-H1792 MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1zT[GlEPTB;MD6wPVYyQCEQvF2= NGroZ2xUSU6JRWK=
MCF7 MoP0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFexNGtKSzVyPUCuNFk3PzdizszN M1nHSnNCVkeHUh?=
NCI-H2122 M3iwWWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4\5OGlEPTB;MD6wPVc1PSEQvF2= MWHTRW5ITVJ?
EFO-27 MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MorwTWM2OD1yLkC5PVk4KM7:TR?= MoD4V2FPT0WU
LB2241-RCC MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4P3PGlEPTB;MD6xNFA2PCEQvF2= MkTMV2FPT0WU
SN12C M3S1dGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFzwWolKSzVyPUCuNVAyODdizszN M1vDUnNCVkeHUh?=
A498 NIT4TYNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWLzTFY3UUN3ME2wMlExOThizszN NUHPRYtTW0GQR1XS
PANC-03-27 NFy4WmtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGPqOIVKSzVyPUCuNVAzQDZizszN NULqWnF6W0GQR1XS
NCI-H1581 NULmfW01T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2rFU2lEPTB;MD6xNFI6KM7:TR?= M3:0SnNCVkeHUh?=
U-87-MG M1zS[Gdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnX4TWM2OD1yLkGwN|A4KM7:TR?= M4nSS3NCVkeHUh?=
G-401 NWHNfFFbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M37TO2lEPTB;MD6xNFM2OyEQvF2= MlG1V2FPT0WU
SiHa NWLFc4RZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYTZcHE6UUN3ME2wMlExPDh4IN88US=> MWrTRW5ITVJ?
U251 NGL0c2xIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWnJR|UxRTBwMUC1NlUh|ryP M2i0SHNCVkeHUh?=
MMAC-SF MWDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXX6W45CUUN3ME2wMlExPTNzIN88US=> M4HzWXNCVkeHUh?=
BB65-RCC M3foNGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mn2xTWM2OD1yLkGwOVU1KM7:TR?= NF;LTHBUSU6JRWK=
NKM-1 MYXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NX35WppRUUN3ME2wMlExPjZ4IN88US=> Mm\5V2FPT0WU
HD-MY-Z MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4\Sc2lEPTB;MD6xNFg4OyEQvF2= M4TJWHNCVkeHUh?=
TGBC11TKB NGTZXnFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NETZbmxKSzVyPUCuNVA6ODNizszN NVq1cIs1W0GQR1XS
COLO-679 MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{nmVmlEPTB;MD6xNVIyOSEQvF2= NIHiOXRUSU6JRWK=
TE-8 M1WwfWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NILhc5BKSzVyPUCuNVEzPjRizszN MYrTRW5ITVJ?
SK-MEL-28 NV\GWodZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Ml:1TWM2OD1yLkGxN|IyKM7:TR?= MkntV2FPT0WU
SH-4 NXPYRZVMT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHvCR2VKSzVyPUCuNVE{PTZizszN M{i3NHNCVkeHUh?=
KALS-1 MlX3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGCwTYFKSzVyPUCuNVE{QTNizszN M3uxfnNCVkeHUh?=
RKO MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEXyNnlKSzVyPUCuNVE4PjRizszN MYTTRW5ITVJ?
OMC-1 NW\iSpUyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWPJR|UxRTBwMUG3PVch|ryP M1\1eXNCVkeHUh?=
BT-549 NX3ZVVcyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFfOeZNKSzVyPUCuNVE4QTlizszN NUHuRm5wW0GQR1XS
NCI-H28 M4XIeGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYXJR|UxRTBwMUG4NVch|ryP MUTTRW5ITVJ?
RXF393 NFLUZXJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXXJR|UxRTBwMUG5PFIh|ryP NV7JTI5bW0GQR1XS
COLO-829 MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NF\ScGNKSzVyPUCuNVIxODVizszN NHK4ZYZUSU6JRWK=
HMV-II MULHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkfxTWM2OD1yLkGyNFIh|ryP MVvTRW5ITVJ?
SW1990 M{HNcmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWjJR|UxRTBwMUKxOVch|ryP Mly3V2FPT0WU
NCI-H1437 NXLCZ|BUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mn60TWM2OD1yLkGyNVU4KM7:TR?= MV;TRW5ITVJ?
SNB75 NHi3c5hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWTJR|UxRTBwMUKxOlkh|ryP MoTmV2FPT0WU
EW-3 M2jXe2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVXJR|UxRTBwMUK2OlEh|ryP NX3Zd|ZyW0GQR1XS
SAS Ml76S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M17HdmlEPTB;MD6xNlY6KM7:TR?= NGnIZm9USU6JRWK=
NCI-H1666 MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnrlTWM2OD1yLkGyO|c1KM7:TR?= NEm3cmZUSU6JRWK=
A375 M2P3bGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{jnW2lEPTB;MD6xNlc4QCEQvF2= M4PHZnNCVkeHUh?=
CAMA-1 MnG1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{\FU2lEPTB;MD6xNlkzPCEQvF2= MXfTRW5ITVJ?
HuP-T4 M1LXemdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MV\JR|UxRTBwMUK5OFMh|ryP M3nocXNCVkeHUh?=
NCI-H292 NF7GNXNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{DPUGlEPTB;MD6xN|EyKM7:TR?= MoDHV2FPT0WU
PC-14 NFP6O3RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWPPfoRUUUN3ME2wMlE{OjFzIN88US=> NVXBUYcxW0GQR1XS
BPH-1 NFy3d5VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NF;Q[WJKSzVyPUCuNVM1OSEQvF2= M{[0d3NCVkeHUh?=
GAK MX\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mnq3TWM2OD1yLkGzOVY4KM7:TR?= NHfqfHhUSU6JRWK=
VMRC-RCZ MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NV\0PZVHUUN3ME2wMlE{PzZ{IN88US=> NYe3dZJ6W0GQR1XS
SK-MEL-24 M3\B[Gdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIG2N4dKSzVyPUCuNVM5PyEQvF2= NYHmNZN4W0GQR1XS
LB831-BLC MmPUS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFjIRo9KSzVyPUCuNVM5QDNizszN NIT0TllUSU6JRWK=
NCI-H2452 NXm1RWJVT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4rlSWlEPTB;MD6xN|k2PiEQvF2= NEjzeXdUSU6JRWK=
RT-112 NEewO5pIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4rFd2lEPTB;MD6xOFA{PSEQvF2= NWjNeFRiW0GQR1XS
GP5d Ml\kS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmjSTWM2OD1yLkG0NVA1KM7:TR?= NIX3cFJUSU6JRWK=
LC-2-ad M2jOcmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2jPXWlEPTB;MD6xOFEzOSEQvF2= MVnTRW5ITVJ?
MPP-89 M3\2UWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MknWTWM2OD1yLkG0NVI2KM7:TR?= M4TEWXNCVkeHUh?=
NUGC-3 NWnIO|RET3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MX;JR|UxRTBwMUS0O|gh|ryP NIe1XY9USU6JRWK=
GI-1 M1K3W2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3W5RWlEPTB;MD6xOFU2QCEQvF2= MUTTRW5ITVJ?
HCC1419 MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFjWW2VKSzVyPUCuNVQ2PzZizszN MWDTRW5ITVJ?
SW1573 MlLUS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIDIS4ZKSzVyPUCuNVQ4PThizszN NXn0OYRKW0GQR1XS
NCI-H2347 MWnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWnTO|hbUUN3ME2wMlE1QDN7IN88US=> NYjwT4NrW0GQR1XS
Mewo NYe0b2hzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVnyfHZJUUN3ME2wMlE1QDh7IN88US=> MVvTRW5ITVJ?
639-V NFPsfWxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2PqRmlEPTB;MD6xOVAyOyEQvF2= M{LrTHNCVkeHUh?=
AsPC-1 NED0dG1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MX;JR|UxRTBwMUWyNlUh|ryP NH7LbI1USU6JRWK=
NCI-H1648 M{XWbGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYiwZm1yUUN3ME2wMlE2OjN{IN88US=> Mk\WV2FPT0WU
786-0 NHK1dpZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NITsTFBKSzVyPUCuNVU{QDFizszN M4rMbHNCVkeHUh?=
ETK-1 MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mlj2TWM2OD1yLkG1PUDPxE1? MVzTRW5ITVJ?
BxPC-3 MorZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4HweGlEPTB;MD6xOVk3PiEQvF2= MVXTRW5ITVJ?
CAL-62 MojKS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4Xx[WlEPTB;MD6xOlE3QSEQvF2= NWK2OZk2W0GQR1XS
HCC1937 NHfYTnhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYLJR|UxRTBwMU[yO|Uh|ryP NGnC[pBUSU6JRWK=
NCI-H1299 M3\JWGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXnJR|UxRTBwMU[yPFUh|ryP M4CyUnNCVkeHUh?=
SW1088 M1y4Rmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoT0TWM2OD1yLkG2OFE{KM7:TR?= MoO1V2FPT0WU
FTC-133 NIrVcIRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkntTWM2OD1yLkG2OVQh|ryP NF3pUphUSU6JRWK=
OC-314 M3n1Umdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXrGd5NzUUN3ME2wMlE3PjlizszN NX\ld5h1W0GQR1XS
SCC-9 MYjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHjic3pKSzVyPUCuNVY4OTZizszN NIHFXlBUSU6JRWK=
HT-1376 NWnUTGM4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3\qbWlEPTB;MD6xOlk{PiEQvF2= NITDRY9USU6JRWK=
U-2-OS NGTCbHNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{iycGlEPTB;MD6xO|E4OyEQvF2= MlL1V2FPT0WU
COLO-824 MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{fXXWlEPTB;MD6xO|I6PCEQvF2= MmXvV2FPT0WU
BB30-HNC MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NF\ae4xKSzVyPUCuNVc{OyEQvF2= NXPpN3JOW0GQR1XS
NCI-H2087 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MX7JR|UxRTBwMUezOlgh|ryP MXHTRW5ITVJ?
NCI-H2170 NES2e4hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3zHc2lEPTB;MD6xO|U{PiEQvF2= NF3oPGdUSU6JRWK=
SK-OV-3 M1fJWGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFvKR5FKSzVyPUCuNVc2PzFizszN MYfTRW5ITVJ?
MZ7-mel MnHxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEfNWmJKSzVyPUCuNVc3PDlizszN NXq1SIFMW0GQR1XS
NCI-H650 MmLuS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3rPOmlEPTB;MD6xO|Y5OiEQvF2= MVjTRW5ITVJ?
KOSC-2 NIHkcVlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEHhS|FKSzVyPUCuNVc4OzRizszN NXvrc3dDW0GQR1XS
SCC-4 NUHmd|dDT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXnJR|UxRTBwMUe3O|ch|ryP MUnTRW5ITVJ?
MDA-MB-157 M33wSWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NF\MbnlKSzVyPUCuNVgxQDJizszN MnG5V2FPT0WU
KYSE-520 NVjyRpZvT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MknuTWM2OD1yLkG4NkDPxE1? MW\TRW5ITVJ?
LK-2 NFLqS5FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoXJTWM2OD1yLkG4N|A{KM7:TR?= MkTzV2FPT0WU
KNS-81-FD NVPUS415T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NH7NWXBKSzVyPUCuNVg{QTRizszN MXHTRW5ITVJ?
IGROV-1 NUTiRVlZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUPJR|UxRTBwMUi0OFMh|ryP MX3TRW5ITVJ?
DEL NFPKRXZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFXQfVNKSzVyPUCuNVg1PSEQvF2= NYWw[pVQW0GQR1XS
NCI-H1395 MmKzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4\oZWlEPTB;MD6xPFY5OiEQvF2= NHroOWtUSU6JRWK=
JEG-3 NVTUUVRNT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4XRZ2lEPTB;MD6xPFcxPSEQvF2= NGnEWYNUSU6JRWK=
BCPAP MmrXS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYKzbINRUUN3ME2wMlE5QDd{IN88US=> MXvTRW5ITVJ?
CAL-27 NHztUnlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoLKTWM2OD1yLkG5NFIzKM7:TR?= NWD1b3ExW0GQR1XS
RD MUHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1XXXGlEPTB;MD6xPVEyOyEQvF2= MmTrV2FPT0WU
RVH-421 M37FR2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFjWUYVKSzVyPUCuNVkyOTZizszN NIXKWWdUSU6JRWK=
Capan-2 MoDsS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVjJR|UxRTBwMUmyOVYh|ryP NEfiVpFUSU6JRWK=
COLO-680N M4HqV2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXjhPWlmUUN3ME2wMlE6OzZ2IN88US=> Ml\3V2FPT0WU
NCI-H1650 M3G1VGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUjJR|UxRTBwMkCwOVch|ryP MVLTRW5ITVJ?
SBC-5 MnzjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2XETmlEPTB;MD6yNFEyQCEQvF2= NYnpSG5YW0GQR1XS
U031 NFvqe4RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkjzTWM2OD1yLkKwOVQ4KM7:TR?= NInUSVRUSU6JRWK=
S-117 MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4HCNmlEPTB;MD6yNFU3PCEQvF2= M4L0SHNCVkeHUh?=
DoTc2-4510 MkDVS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUTKN3JVUUN3ME2wMlIxPzZ7IN88US=> MX;TRW5ITVJ?
AM-38 NUT5eWdHT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3rCbWlEPTB;MD6yNFg1QCEQvF2= MUXTRW5ITVJ?
A172 MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXLJR|UxRTBwMkGwNlIh|ryP M{XyfnNCVkeHUh?=
HPAF-II NUnWTGxwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGrOcnpKSzVyPUCuNlEzPjRizszN M1rNfHNCVkeHUh?=
769-P MlniS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1P1OmlEPTB;MD6yNVI5KM7:TR?= NGPUUHJUSU6JRWK=
MFE-280 NFz3TplIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVfJR|UxRTBwMkGyPVgh|ryP NG\hW4pUSU6JRWK=
TE-9 MlTTS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFP3VYxKSzVyPUCuNlE4QDZizszN M2rJN3NCVkeHUh?=
C2BBe1 MmLWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1PmfGlEPTB;MD6yNlE6KM7:TR?= NUO2NJhxW0GQR1XS
EoL-1-cell MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVvKXmtGUUN3ME2wMlIzOjB|IN88US=> NV7INI4yW0GQR1XS
G-361 MnL1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGC4foZKSzVyPUCuNlI3QDJizszN M4rZbXNCVkeHUh?=
KYSE-270 NVH4eHdDT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4XnOGlEPTB;MD6yN|A5PCEQvF2= NELxU3RUSU6JRWK=
TK10 MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEPBPYVKSzVyPUCuNlMyOTdizszN Ml\SV2FPT0WU
ML-2 NUDnd4JnT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3r3SWlEPTB;MD6yN|EyQSEQvF2= M2S2bnNCVkeHUh?=
MHH-ES-1 NFfPPZRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVTJR|UxRTBwMkO2PFEh|ryP NFHid2dUSU6JRWK=
BHY MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnPHTWM2OD1yLkKzOlkyKM7:TR?= Mlr2V2FPT0WU
LS-513 M1zXfWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXX3VnZOUUN3ME2wMlI{QTZzIN88US=> NYjsZY1LW0GQR1XS
COLO-678 NEj2[FVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MonkTWM2OD1yLkK0NFQ1KM7:TR?= Ml\MV2FPT0WU
NCI-H747 MoHIS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVnJR|UxRTBwMkSxOlkh|ryP NGLkSFJUSU6JRWK=
K5 NVTo[XZTT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlrrTWM2OD1yLkK0N|gh|ryP MXTTRW5ITVJ?
OS-RC-2 NWPhRmR2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mle3TWM2OD1yLkK0OVA6KM7:TR?= NHfEVpJUSU6JRWK=
KINGS-1 M1Pzb2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkfMTWM2OD1yLkK0OVI6KM7:TR?= NEThNmNUSU6JRWK=
SCC-25 NYfmNJZUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnvNTWM2OD1yLkK0OVY{KM7:TR?= NGTpeoZUSU6JRWK=
CAPAN-1 NVPuO3hlT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NV\3WGFRUUN3ME2wMlI1Pzh|IN88US=> NGOyeJZUSU6JRWK=
ESS-1 M36ySmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUfkVnFMUUN3ME2wMlI1QDB3IN88US=> MVzTRW5ITVJ?
TE-6 NH;jUopIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXzJR|UxRTBwMkW3OUDPxE1? M3;D[XNCVkeHUh?=
LB2518-MEL MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWjJR|UxRTBwMkW3O|ch|ryP MofNV2FPT0WU
COLO-800 MULHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkDBTWM2OD1yLkK1PFEzKM7:TR?= MVPTRW5ITVJ?
LU-134-A MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnPmTWM2OD1yLkK2NVM3KM7:TR?= MnjRV2FPT0WU
NCI-H1155 M{nhNWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWfjVm0zUUN3ME2wMlI3OTZ{IN88US=> NFTWZlRUSU6JRWK=
MFM-223 M{jFVWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3K5[WlEPTB;MD6yOlM3OyEQvF2= M3jKOHNCVkeHUh?=
HTC-C3 MnzaS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3;DRmlEPTB;MD6yOlUxPiEQvF2= MkTpV2FPT0WU
HCT-116 MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NF;IVWRKSzVyPUCuNlY2QTlizszN NHLGflFUSU6JRWK=
Ca-Ski M1PNdWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoPFTWM2OD1yLkK2Olc5KM7:TR?= NIr0NplUSU6JRWK=
SBC-1 MnX4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWnKfJhSUUN3ME2wMlI3PzR{IN88US=> MoDSV2FPT0WU
NB69 MoixS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3fye2lEPTB;MD6yO|A5PyEQvF2= MY\TRW5ITVJ?
J82 MoDaS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnH3TWM2OD1yLkK3NlY2KM7:TR?= MkTOV2FPT0WU
U-118-MG MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWTJR|UxRTBwMke1O|kh|ryP M3PVfXNCVkeHUh?=
NCI-H1355 MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmfMTWM2OD1yLkK4NFc1KM7:TR?= MVnTRW5ITVJ?
NCI-H1048 MlzIS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NF:xeoNKSzVyPUCuNlg6PTZizszN MV;TRW5ITVJ?
SW954 M3rjSWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnXSTWM2OD1yLkK5NlI4KM7:TR?= M3LSfHNCVkeHUh?=
NMC-G1 M4K5cGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{jzVGlEPTB;MD6yPVI4PyEQvF2= M4q2SXNCVkeHUh?=
SW1710 MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYfJR|UxRTBwMkm0PVQh|ryP MkfIV2FPT0WU
KY821 MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIX3UItKSzVyPUCuNlk5PzJizszN NGLGbmVUSU6JRWK=
HCC38 M4ThSWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEnaWpNKSzVyPUCuN|AxPzhizszN NH\weXdUSU6JRWK=
NCI-SNU-5 NET6[4VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEDP[2tKSzVyPUCuN|A2PCEQvF2= NGXySJRUSU6JRWK=
ES8 MkHhS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkTlTWM2OD1yLkOwO|g1KM7:TR?= NELWeYlUSU6JRWK=
COLO-792 MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MULJR|UxRTBwM{GyOVEh|ryP NELRT3ZUSU6JRWK=
BFTC-905 MUHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NELvflRKSzVyPUCuN|E2OjFizszN MmnMV2FPT0WU
ChaGo-K-1 NXXLclFmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NG[yTVhKSzVyPUCuN|E4OTVizszN NFq4V25USU6JRWK=
Daoy MmfGS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWfJR|UxRTBwM{G3NlMh|ryP MULTRW5ITVJ?
SJSA-1 NFLJ[2lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHPXZ2hKSzVyPUCuN|E5PDdizszN MULTRW5ITVJ?
KNS-62 M4\YXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mli0TWM2OD1yLkOyNFg5KM7:TR?= NFXacZNUSU6JRWK=
CAKI-1 M3r3U2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWrJR|UxRTBwM{KxNVEh|ryP NH;0cWlUSU6JRWK=
UACC-62 MorHS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NH[1bVBKSzVyPUCuN|IzOjdizszN Mmm1V2FPT0WU
HuCCT1 NYnsZ5ZPT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3vCc2lEPTB;MD6zNlI5OyEQvF2= MoXvV2FPT0WU
CTB-1 M{f4SGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{nqUGlEPTB;MD6zNlc2OyEQvF2= NYiyVI1oW0GQR1XS
NTERA-S-cl-D1 Mmi4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnG3TWM2OD1yLkOyPFM3KM7:TR?= NXTKOnVvW0GQR1XS
T-24 MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MknRTWM2OD1yLkOzNVU6KM7:TR?= MWPTRW5ITVJ?
KYSE-70 MWDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{nCeWlEPTB;MD6zN|I5OyEQvF2= MYnTRW5ITVJ?
SW626 M3;JS2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M33Ye2lEPTB;MD6zN|U{OiEQvF2= MmrBV2FPT0WU
LB996-RCC MnrJS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NX\aXpA4UUN3ME2wMlM{PjF7IN88US=> NFKzXm1USU6JRWK=
DMS-273 NUXnbZRLT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmrBTWM2OD1yLkOzPVE3KM7:TR?= NVzLZlc2W0GQR1XS
SW1783 NIfGemVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIXmbVJKSzVyPUCuN|M6QTdizszN MWnTRW5ITVJ?
KU812 M13tcmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NU\WUGR{UUN3ME2wMlM1ODN6IN88US=> MYnTRW5ITVJ?
HSC-2 NXjiSFcyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEjzdXBKSzVyPUCuN|QxPTNizszN M1XUWHNCVkeHUh?=
A3-KAW NYfvelNNT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4jHSGlEPTB;MD6zOFE3OiEQvF2= M2Wy[nNCVkeHUh?=
COLO-684 MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4Hm[GlEPTB;MD6zOFUxOSEQvF2= MXfTRW5ITVJ?
NCI-H2405 NFzJdI9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NV;DcWtkUUN3ME2wMlM1PjNzIN88US=> NFvQR4VUSU6JRWK=
NCI-H2228 M2qwXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHzqOIJKSzVyPUCuN|U{PTdizszN NV\sWWRIW0GQR1XS
NB13 M4nEUmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Ml;JTWM2OD1yLkO2PFI6KM7:TR?= M17id3NCVkeHUh?=
no-11 NVzGPIVOT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MV3JR|UxRTBwM{[5OUDPxE1? MXXTRW5ITVJ?
DK-MG NX71N4J7T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1nBWGlEPTB;MD6zO|E5QCEQvF2= NHHCdIJUSU6JRWK=
NBsusSR M{DsZmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYTJR|UxRTBwM{eyPFUh|ryP Ml7FV2FPT0WU
KP-N-YS NVfKOpBjT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkXyTWM2OD1yLkO3OFY{KM7:TR?= M3i2XXNCVkeHUh?=
CFPAC-1 MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEK1d2RKSzVyPUCuN|c2OThizszN M3vuXXNCVkeHUh?=
KARPAS-45 MnzaS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnXQTWM2OD1yLkO3PFYzKM7:TR?= MmfoV2FPT0WU
NCI-H1793 MnrWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmDFTWM2OD1yLkO4OVEh|ryP MW\TRW5ITVJ?
HCE-T NYfW[olYT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXzkWJBoUUN3ME2wMlM5PjB|IN88US=> NXHp[pJoW0GQR1XS
NCI-H520 NGDw[lVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MonxTWM2OD1yLkO4O|A{KM7:TR?= NXfne3ZuW0GQR1XS
HCC2157 MlnJS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHzjUo9KSzVyPUCuN|g4QDFizszN NFrPOXdUSU6JRWK=
EW-18 NGr1eVJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYjvN4JlUUN3ME2wMlM5QTRzIN88US=> MnfZV2FPT0WU
RO82-W-1 MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NU\nVowxUUN3ME2wMlM6Pjl7IN88US=> NVzke2dQW0GQR1XS
HuP-T3 NX\B[5BrT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{KyS2lEPTB;MD60NFE1OyEQvF2= MX\TRW5ITVJ?
PANC-10-05 MoXnS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHTPZ4FKSzVyPUCuOFEyPyEQvF2= NE\BTIdUSU6JRWK=
NCI-H1703 M{fkRmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXz6enhDUUN3ME2wMlQyPDR4IN88US=> M3T3b3NCVkeHUh?=
TE-10 NGfqNmFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXPJR|UxRTBwNEG0OFch|ryP MojyV2FPT0WU
HOS M4PNbmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{\zTGlEPTB;MD60NVY5OiEQvF2= MVHTRW5ITVJ?
LN-405 M3nJW2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGCwfZlKSzVyPUCuOFE3QDdizszN MoTpV2FPT0WU
A427 MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MW\JR|UxRTBwNEG5PFEh|ryP NXGwVYVsW0GQR1XS
CAL-12T NYLT[FBbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M376TmlEPTB;MD60Nlc5KM7:TR?= NGnXSItUSU6JRWK=
SW756 MlzrS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYnJR|UxRTBwNESxPFMh|ryP M1PzZXNCVkeHUh?=
YAPC NFSxS4ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NY\JXFIxUUN3ME2wMlQ2ODhizszN NHfKR3ZUSU6JRWK=
GOTO MnjnS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4TtdmlEPTB;MD60OVE3KM7:TR?= NID1fmVUSU6JRWK=
C3A NEjIVWNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4[0N2lEPTB;MD60OVQ{PyEQvF2= M17ORnNCVkeHUh?=
UM-UC-3 M{HF[2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEXjRmhKSzVyPUCuOFU1PyEQvF2= MXjTRW5ITVJ?
NCI-H1573 MX3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWT2bI1pUUN3ME2wMlQ2PTZ7IN88US=> MXjTRW5ITVJ?
LS-411N NHv4[5NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVnz[lQ6UUN3ME2wMlQ3PTJ5IN88US=> NGf6VIxUSU6JRWK=
COR-L23 NFnORVNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHPhdGZKSzVyPUCuOFY4PjRizszN M4LIfnNCVkeHUh?=
HCE-4 M3e4TGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M165UWlEPTB;MD60O|Q1PiEQvF2= Ml;uV2FPT0WU
NCI-H2291 MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFPXPHBKSzVyPUCuOFc5QTZizszN NIjWcJBUSU6JRWK=
A101D M37pU2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHSzNGpKSzVyPUCuOFgxPTNizszN MVrTRW5ITVJ?
HT-3 NYL5TIJ6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHPOPIxKSzVyPUCuOFgzOTdizszN MVvTRW5ITVJ?
HOP-62 NGjkNHlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWPke4ZoUUN3ME2wMlQ6QDZ3IN88US=> NFe0O2tUSU6JRWK=
PC-3 NWDSV4l{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnfpTWM2OD1yLkWxOVA4KM7:TR?= NXG0bm1SW0GQR1XS
CTV-1 NWfwOnlIT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYXXNI05UUN3ME2wMlUzPjZ7IN88US=> NVyxU5VVW0GQR1XS
PANC-08-13 NYLKZ2tYT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2rRZWlEPTB;MD61N|E4PyEQvF2= MXfTRW5ITVJ?
CAL-120 MmrRS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MX;JR|UxRTBwNUOzPVkh|ryP MkS4V2FPT0WU
UMC-11 NW[zPFZvT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NG[wXo5KSzVyPUCuOVUzOzRizszN MmW2V2FPT0WU
MSTO-211H MUHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXHJR|UxRTBwNUW3OlIh|ryP NE[4SmtUSU6JRWK=
NCI-H2126 MlviS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4jjXmlEPTB;MD61OlgyPSEQvF2= NF\PT4lUSU6JRWK=
SNU-C2B NHLtVZNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWDxTHBjUUN3ME2wMlU4QTd5IN88US=> NVHqVo9DW0GQR1XS
DBTRG-05MG NXT2d4VzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVfoXHltUUN3ME2wMlU5ODV|IN88US=> NGT6d4pUSU6JRWK=
MKN1 NVvBdXFqT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWXJR|UxRTBwNUi3PFMh|ryP MXzTRW5ITVJ?
ES3 NYCwRYJpT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWLJR|UxRTBwNUmxNlQh|ryP NEHCbHNUSU6JRWK=
OVCAR-3 NI\JUYVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFvleFZKSzVyPUCuOVk{PDFizszN NUjTVHhxW0GQR1XS
ACHN MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M37LTGlEPTB;MD62NFU3QSEQvF2= Mm[1V2FPT0WU
SW872 M{jTcWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2PSb2lEPTB;MD62NFc3OyEQvF2= M{nVWHNCVkeHUh?=
CP66-MEL MkTOS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NH7heGlKSzVyPUCuOlA6PjlizszN NIi2OWFUSU6JRWK=
NCI-H661 MoXSS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmPiTWM2OD1yLk[xNVA1KM7:TR?= NEPPZ41USU6JRWK=
UACC-893 NXXYPIFwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NV2weINxUUN3ME2wMlY{PjhzIN88US=> NFTlZnZUSU6JRWK=
JVM-3 M1qzVWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnTiTWM2OD1yLk[zPFA1KM7:TR?= M1v5fHNCVkeHUh?=
SF268 MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{LvOGlEPTB;MD62OFM1QSEQvF2= MlHtV2FPT0WU
OCI-AML2 MUjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4fMeGlEPTB;MD62OVM6PyEQvF2= MYTTRW5ITVJ?
RPMI-8226 MkLKS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkHZTWM2OD1yLk[2N|I{KM7:TR?= MnjCV2FPT0WU
MKN28 NVTBdYF7T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXfoc2FRUUN3ME2wMlY3PjJ2IN88US=> NH\W[oVUSU6JRWK=
MDA-MB-453 NHSxOXRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mon3TWM2OD1yLk[3NVgh|ryP MnfkV2FPT0WU
BV-173 MmDuS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXi4c2d3UUN3ME2wMlY5Pjd7IN88US=> M3;zZnNCVkeHUh?=
NCI-H358 MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIG3V3BKSzVyPUCuOlg4OjZizszN Mly4V2FPT0WU
NCI-H1651 NIntVWhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1q1e2lEPTB;MD63JO69VQ>? NIf4OWJUSU6JRWK=
MDA-MB-415 NVO5WFE4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1j4[GlEPTB;MD63NFgzQSEQvF2= Ml2zV2FPT0WU
8305C MojZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4TN[2lEPTB;MD63NlQ6QCEQvF2= Mkn4V2FPT0WU
EFM-19 NYjqUoc3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXPBWWN5UUN3ME2wMlc{PjdzIN88US=> MUTTRW5ITVJ?
RERF-LC-MS NWDHfndpT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUP1dI01UUN3ME2wMlc1PjF|IN88US=> NXrIbIRCW0GQR1XS
A388 M3nySGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYrPeHJEUUN3ME2wMlc3PDZ5IN88US=> MlLmV2FPT0WU
GI-ME-N NHeyOJpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEnYbpRKSzVyPUCuO|czOzVizszN NUniNXlyW0GQR1XS
IGR-1 MYjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEX3UYlKSzVyPUCuO|kxPDNizszN NFS5WZBUSU6JRWK=
LNCaP-Clone-FGC MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{f3cWlEPTB;MD64NFAxPCEQvF2= NH;xcolUSU6JRWK=
SK-MEL-3 MoLTS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2Dp[2lEPTB;MD64NVUxQCEQvF2= MXXTRW5ITVJ?
UACC-257 Ml3zS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NX:wOZhOUUN3ME2wMlgzOjNzIN88US=> MWrTRW5ITVJ?
OE33 NH\yVFJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHHZc49KSzVyPUCuPFUyODFizszN NV7CO|FOW0GQR1XS
QIMR-WIL NFXRTYlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{nTc2lEPTB;MD64OVE1OSEQvF2= M{HKdHNCVkeHUh?=
NCI-H2009 NETvNWhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkjITWM2OD1yLki1N|EyKM7:TR?= M3fWUXNCVkeHUh?=
NCI-H522 M3XpNWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NV\qfG5CUUN3ME2wMlg4Pzh|IN88US=> M3PkdnNCVkeHUh?=
Saos-2 MmXvS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXjxcWhZUUN3ME2wMlg4QDdzIN88US=> M2LhT3NCVkeHUh?=
NB17 NXzPNoFXT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIDaWJVKSzVyPUCuPFgxOjVizszN M{Tyb3NCVkeHUh?=
D-392MG NVHkS3Q3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVG3TI9sUUN3ME2wMlg6OzV4IN88US=> NEL4VYlUSU6JRWK=
SHP-77 M{\TW2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mo\vTWM2OD1yLkmwOFg2KM7:TR?= MVrTRW5ITVJ?
SK-MEL-30 NWe2PXk6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXPJR|UxRTBwOUGxPFUh|ryP NGfUd2pUSU6JRWK=
GCIY M4fxcGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUnpPXZiUUN3ME2wMlkyQDR|IN88US=> MUPTRW5ITVJ?
HCC70 MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlHhTWM2OD1yLkmyNFU6KM7:TR?= NFuwTGhUSU6JRWK=
LU-65 NX;PZ3lZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWix[WxkUUN3ME2wMlkzPTlzIN88US=> MnfQV2FPT0WU
NCI-H1563 NVjWUG5TT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWf0cHQyUUN3ME2wMlk1QDZ3IN88US=> MmnIV2FPT0WU
KURAMOCHI MoT3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NY\ud2h4UUN3ME2wMlk2OTl{IN88US=> M3fzOnNCVkeHUh?=
PA-1 MnLzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWHJR|UxRTBwOUW0NlQh|ryP NV;Sc5gxW0GQR1XS
NOS-1 M4KzdGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnPWTWM2OD1yLkm3OFg6KM7:TR?= NETLeY1USU6JRWK=
NCI-H69 MnTQS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVLYRlF[UUN3ME2wMlk4PjN2IN88US=> M2jNdnNCVkeHUh?=
KYSE-450 MmPDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2TqWWlEPTB;MD65PFYzPiEQvF2= NWTBO3lQW0GQR1XS
8505C NUnFXWF[T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEXPdo9KSzVyPUCuPVk6QDJizszN Ml7vV2FPT0WU
TGBC24TKB NUTkT5g1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVPJR|UxRTFwMECwPFQh|ryP NHHhdm9USU6JRWK=
PFSK-1 M3ftPWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVrJR|UxRTFwMEG0Nlgh|ryP MUPTRW5ITVJ?
EKVX NFzaWW5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mof5TWM2OD1zLkCzNVIyKM7:TR?= NXjiSGxlW0GQR1XS
RCM-1 M3zOUmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NULZN|I1UUN3ME2xMlA2PTB5IN88US=> MULTRW5ITVJ?
SW900 NVn2[m9HT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1fZW2lEPTB;MT6wO|g{KM7:TR?= M3;hb3NCVkeHUh?=
D-542MG NHHPR3RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NX\1SG9[UUN3ME2xMlA4QDV3IN88US=> M4TWbHNCVkeHUh?=
SK-PN-DW MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoXpTWM2OD1zLkGwNFU3KM7:TR?= NGfJfIJUSU6JRWK=
NCI-H727 MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWW0XZh1UUN3ME2xMlExOTV2IN88US=> M3jyTXNCVkeHUh?=
SW837 NHTiUoNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnfuTWM2OD1zLkGwPVU1KM7:TR?= NEnuNHdUSU6JRWK=
BT-20 NXrFd41qT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFrNZ5VKSzVyPUGuNVEzODRizszN M1rmN3NCVkeHUh?=
RH-18 NX3aN2szT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWnxeWMyUUN3ME2xMlE{OTB|IN88US=> MUPTRW5ITVJ?
TE-12 MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmLFTWM2OD1zLkGzN|M{KM7:TR?= NWTqb48yW0GQR1XS
NB10 M330Vmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYDJR|UxRTFwMUOzOFQh|ryP MX;TRW5ITVJ?
AU565 NHyzd3BIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NV3oSmVXUUN3ME2xMlE2QTd|IN88US=> NUnWXpdtW0GQR1XS
OAW-42 NHzpW4NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MY\JR|UxRTFwMUizNFYh|ryP Mm\GV2FPT0WU
DJM-1 MUDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NILzNGpKSzVyPUGuNVk5QDFizszN MlnuV2FPT0WU
HH M{Hwb2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXnJR|UxRTFwMkO4N|Eh|ryP NH3SeJBUSU6JRWK=
LAMA-84 MoC1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4fTcGlEPTB;MT6yO|M6PCEQvF2= NWHaRpBlW0GQR1XS
KNS-42 NGrTT|NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWfJR|UxRTFwM{CyPVYh|ryP NXjyN2x4W0GQR1XS
NCI-H2052 MlqyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1;rVWlEPTB;MT6zNFUxPyEQvF2= NYn3cGVjW0GQR1XS
MLMA MYjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXzIfGN[UUN3ME2xMlMzPDB5IN88US=> NX3Ge4JkW0GQR1XS
NB12 M2DMTmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoeyTWM2OD1zLkO1OlM3KM7:TR?= M4PWd3NCVkeHUh?=
NCI-H1838 NFXjVHRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{\CNGlEPTB;MT6zOlMxPiEQvF2= MYTTRW5ITVJ?
NCI-H526 MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3nIfGlEPTB;MT6zO|g2OyEQvF2= MWPTRW5ITVJ?
LS-123 M4HYOWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MojlTWM2OD1zLkO5NFk1KM7:TR?= NVPD[lRMW0GQR1XS
HDLM-2 MUHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1rQ[mlEPTB;MT6zPVI4OSEQvF2= NFeySopUSU6JRWK=
MC-IXC NYfsRZJvT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEDQbm1KSzVyPUGuOFI{PzFizszN NWLwfnJkW0GQR1XS
HCT-15 NEPob4RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHjuVYNKSzVyPUGuOFMxPjhizszN MU\TRW5ITVJ?
NCI-H596 MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXLJR|UxRTFwNEWwOlEh|ryP NXfpWZJlW0GQR1XS
ZR-75-30 NVL6b5NxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mm\5TWM2OD1zLkS3NFgzKM7:TR?= MWXTRW5ITVJ?
A704 NIrETHhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWLUWlhEUUN3ME2xMlY3PTZ|IN88US=> NV3N[WJJW0GQR1XS
OVCAR-4 NXPQcZdTT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2LON2lEPTB;MT62PVYxPyEQvF2= MWnTRW5ITVJ?
SW1417 NHPCPJFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3zBfGlEPTB;MT63Nlg1QSEQvF2= Mo\qV2FPT0WU
CAS-1 MmnkS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWTJR|UxRTFwN{O5N|Yh|ryP M{ixXXNCVkeHUh?=
IST-SL1 NUP3T284T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mn\5TWM2OD1zLke5O|U6KM7:TR?= NG\Wd4VUSU6JRWK=
A253 NXPTVGNHT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYfJR|UxRTFwOEKyN|kh|ryP M3rQ[nNCVkeHUh?=
EW-16 MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{jSXGlEPTB;MT64Nlg4PSEQvF2= M3HJSXNCVkeHUh?=
SK-NEP-1 M2H0fmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnfZTWM2OD1zLki2PVg5KM7:TR?= NHHEdXNUSU6JRWK=
NCI-H226 M4TvR2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWPy[4pHUUN3ME2xMlg6OzV7IN88US=> MXfTRW5ITVJ?
HOP-92 M1zXOGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NH\zOWRKSzVyPUGuPVYxQTlizszN M{K4dHNCVkeHUh?=
NCI-H441 MX7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3jQWWlEPTB;Mj6wNlM{PyEQvF2= NWrTT29QW0GQR1XS
LU-139 MljDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIO0b4dKSzVyPUKuNFMyOTRizszN NWXYUoxTW0GQR1XS
SJRH30 M371PWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFnTWnZKSzVyPUKuNFQzPTNizszN M1;aU3NCVkeHUh?=
MG-63 NHn4d2FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlTWTWM2OD1{LkG0NVEyKM7:TR?= NEjMV2xUSU6JRWK=
NH-12 NYfHb|J[T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIjuUZJKSzVyPUKuNVUxODZizszN MXzTRW5ITVJ?
NB7 NEDhUJVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmPITWM2OD1{LkG5Olc{KM7:TR?= NXzib2x5W0GQR1XS
LB771-HNC M4LZcGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYPJR|UxRTJwMkC1PVUh|ryP M1fKbXNCVkeHUh?=
HCC1569 MVTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NX7vTWZ{UUN3ME2yMlI1PTh|IN88US=> MmH6V2FPT0WU
D-283MED MmHjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUfJR|UxRTJwMkS3PFIh|ryP MVLTRW5ITVJ?
J-RT3-T3-5 MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{OxU2lEPTB;Mj6yOVM2OSEQvF2= MnPoV2FPT0WU
ATN-1 MnzrS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVXR[IxPUUN3ME2yMlM{ODh{IN88US=> NF3oUldUSU6JRWK=
HCC1954 NFLhZYdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVfJR|UxRTJwM{S0NFgh|ryP MWjTRW5ITVJ?
SCC-15 NXPnVFg2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1nFR2lEPTB;Mj6zPVMyOiEQvF2= NEO1S5JUSU6JRWK=
COLO-668 NGL0dXRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MULJR|UxRTJwNEOyJO69VQ>? M2roSXNCVkeHUh?=
LB373-MEL-D NIm0[pVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4\iWmlEPTB;Mj61OFY4PyEQvF2= NYDL[ZlzW0GQR1XS
no-10 NUKzT4J7T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUjJR|UxRTJwNUS5OFch|ryP MnzwV2FPT0WU
HT-1197 MnjSS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEHaSG5KSzVyPUKuOlMyQDhizszN MXTTRW5ITVJ?
DU-145 M2m5PWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXrJR|UxRTJwN{mxOlIh|ryP MWLTRW5ITVJ?
SK-N-AS MkTsS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYrJR|UxRTJwOES2PVIh|ryP MXnTRW5ITVJ?
MOLT-4 MoflS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1XSU2lEPTB;Mj64OVMzOiEQvF2= NWPkfm1nW0GQR1XS
EW-22 MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXHCS4ZsUUN3ME2yMlkzQDRzIN88US=> MY\TRW5ITVJ?
DB NXPN[3VvT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2\2V2lEPTB;Mj65O|c2QSEQvF2= M1vpcHNCVkeHUh?=
HL-60 NUPRO4cyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Ml24TWM2OD1|LkC0N|c3KM7:TR?= NX3ydmN[W0GQR1XS
SK-N-DZ MkK2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MljVTWM2OD1|LkC1NFc2KM7:TR?= MmDwV2FPT0WU
NY M{job2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2nINWlEPTB;Mz6wPFU1OiEQvF2= MojBV2FPT0WU
T47D MmrKS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NY\6[pR[UUN3ME2zMlExPTV6IN88US=> MX;TRW5ITVJ?
NCI-H2029 NYTNfnh6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUfJR|UxRTNwMkK0O|ch|ryP MXnTRW5ITVJ?
KARPAS-299 M3r2dGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIHVVppKSzVyPUOuNlYxOjdizszN MnXQV2FPT0WU
KM-H2 M1LDeWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGXhUHZKSzVyPUOuN|A3QCEQvF2= MUDTRW5ITVJ?
CHP-134 M{jCdWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{\ET2lEPTB;Mz60O|M6KM7:TR?= NXHuUWhEW0GQR1XS
22RV1 Mm\qS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWnJR|UxRTNwNEmxOlgh|ryP M3HDS3NCVkeHUh?=
NB5 MlvDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MX;JR|UxRTNwNUC2PFkh|ryP MmjmV2FPT0WU
CW-2 MUjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1L0PWlEPTB;Mz61OVMyPCEQvF2= Mn7RV2FPT0WU
EFO-21 M3;ufWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGHYdm1KSzVyPUOuOVY6PCEQvF2= NInufIhUSU6JRWK=
HuH-7 MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHrFPIxKSzVyPUOuOVg1OTRizszN M3rNeXNCVkeHUh?=
ALL-PO MoK4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUDUXG55UUN3ME2zMlYzOzN3IN88US=> NW[5ZY5UW0GQR1XS
EM-2 NWXwdVA2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWPJR|UxRTNwNkmwNVEh|ryP MojpV2FPT0WU
KLE MnvMS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2fvNmlEPTB;Mz63N|AzQSEQvF2= NVHRcpRvW0GQR1XS
NEC8 NWfFXopLT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Ml3DTWM2OD1|LkmxPFA5KM7:TR?= MnPyV2FPT0WU
KP-N-YN M3vUVmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{nu[mlEPTB;Mz65N|Q4PiEQvF2= MUTTRW5ITVJ?
SK-MEL-1 MYPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIe2eFhKSzVyPUSuNFM2OThizszN NF;qO5RUSU6JRWK=
CAL-54 MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkfITWM2OD12LkC1PVEh|ryP M1;rOXNCVkeHUh?=
MS-1 MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWLTSlVkUUN3ME20MlE3OTV3IN88US=> NFnldpNUSU6JRWK=
NCI-H209 NFH0WXpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYjRRZVVUUN3ME20MlI6QTl7IN88US=> NEnUc25USU6JRWK=
NOMO-1 Mo\ES5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFnmXnJKSzVyPUSuN|IyOzFizszN M1T0[HNCVkeHUh?=
RPMI-2650 MnHGS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlTKTWM2OD12LkO2N|I4KM7:TR?= M4no[nNCVkeHUh?=
NCI-H810 MkHYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGjjeXpKSzVyPUSuN|k4OzZizszN MVfTRW5ITVJ?
Ca9-22 MoL0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYfMR|lRUUN3ME20MlQ2PjlzIN88US=> NXfkVolbW0GQR1XS
ES4 M1XDcmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXvJR|UxRTRwNEewPVUh|ryP MVrTRW5ITVJ?
ES6 Ml\HS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NX3JfVJDUUN3ME20MlQ6PjV5IN88US=> MUfTRW5ITVJ?
DMS-114 NXfMcZI6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVHJR|UxRTRwNUS2PVEh|ryP NYHvXmVuW0GQR1XS
ONS-76 NITHT4NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4i5UmlEPTB;ND61O|k2KM7:TR?= M{jFXnNCVkeHUh?=
K-562 NHnVd2FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYPJR|UxRTRwN{O4NVQh|ryP MXvTRW5ITVJ?
MHH-NB-11 MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mly5TWM2OD12Lke1OFYyKM7:TR?= NFr6RYVUSU6JRWK=
Calu-3 NHHydItIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Ml2zTWM2OD12Lke4OVQ5KM7:TR?= MW\TRW5ITVJ?
HT55 NULGflY1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGe5UlFKSzVyPUSuPFQ2PDVizszN M3zwb3NCVkeHUh?=
SK-N-FI MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUnjS|BkUUN3ME20Mlg2ODB7IN88US=> NF7JOWtUSU6JRWK=
ES1 NInOXmZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mn7KTWM2OD12Lki2NFU4KM7:TR?= NGnMOYlUSU6JRWK=
SF126 Mo[xS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGnZWoxKSzVyPUSuPVMyQDRizszN NUDHVmN4W0GQR1XS
ES5 M1HO[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmX2TWM2OD13LkGyOFI4KM7:TR?= M{noOHNCVkeHUh?=
LoVo NED3OYlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MY\JR|UxRTVwMUW4O|Eh|ryP MV\TRW5ITVJ?
SNU-387 M3Xn[Gdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoDNTWM2OD13LkOyN|M6KM7:TR?= M{fJcnNCVkeHUh?=
C8166 M1zRUmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFKwVZNKSzVyPUWuN|Y{OzlizszN NYfQOnl7W0GQR1XS
LS-1034 M3zr[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVfJR|UxRTVwNEKzNFch|ryP NEf5[nJUSU6JRWK=
GR-ST MkXxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NH;YbI5KSzVyPUWuOVIzODFizszN MmLPV2FPT0WU
NCI-H1092 NF3zW4RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlrVTWM2OD13LkeyPFQ{KM7:TR?= MV;TRW5ITVJ?
647-V NHHEfIlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWTJR|UxRTVwN{S3NFYh|ryP MnzzV2FPT0WU
EW-13 M37Hb2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXHJR|UxRTVwN{[2Nlch|ryP NIDDZZlUSU6JRWK=
KGN MYXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mn7zTWM2OD14LkC5PVIyKM7:TR?= NETmWGdUSU6JRWK=
D-423MG M2G5Nmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkTOTWM2OD14LkSwNlg1KM7:TR?= NYTPZZRMW0GQR1XS
ECC10 NEDGeFBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYrwdZRLUUN3ME23MlExOTBzIN88US=> NWLaS5J1W0GQR1XS
TE-5 M3nvNmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{XFRWlEPTB;Nz60NVI6QCEQvF2= NFvkOGlUSU6JRWK=
P12-ICHIKAWA M33sT2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MX3JR|UxRTdwNEW1NlMh|ryP NUXFd4pDW0GQR1XS
NCI-H82 MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{SxOGlEPTB;Nz60OVcxOSEQvF2= M3PLPHNCVkeHUh?=
NCI-H1993 MoHCS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmfMTWM2OD15LkizNFY{KM7:TR?= NUX5d5NUW0GQR1XS
RH-1 MVHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NILRfJZKSzVyPUeuPFUzPDRizszN NY\1NIxHW0GQR1XS
SW948 NWS4cGN3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWHJR|UxRTdwOU[wOFkh|ryP M4e4TnNCVkeHUh?=
CAL-33 MXzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NH3z[ppKSzVyPUeuPVk6OzhizszN MnLnV2FPT0WU
U-266 MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFW3eZdKSzVyPUiuNVU4PzdizszN M4TBcnNCVkeHUh?=
CAL-72 NFjKbWhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1q1bmlEPTB;OD6yNFMzKM7:TR?= NGDwb2NUSU6JRWK=
SNU-423 M1z1RWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYrJR|UxRTlwM{[2OlYh|ryP Mmn6V2FPT0WU
KG-1 NUXVSI5nT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGe5SYRKSzVyPUmuOVg1PTZizszN MYfTRW5ITVJ?
HCC1395 NWTiSmVKT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmPtTWM2OD17LkmyN|UzKM7:TR?= NHHmZXVUSU6JRWK=
BE-13 MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHiwOY1KSzVyPUGwMlg5QTJizszN NI\YTplUSU6JRWK=
MKN7 MkmxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXf1Z5J7UUN3ME2xNE46PzZ3IN88US=> M2TnbnNCVkeHUh?=
697 NWXDeGk2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXvJR|UxRTFzLkG0O|Ih|ryP MnLVV2FPT0WU
LU-135 NFfWOItIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWHJR|UxRTFzLkKzNFch|ryP M1:4VnNCVkeHUh?=
ES7 NXi1Z3FqT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3rXNWlEPTB;MUGuN|MyOyEQvF2= M2LtcnNCVkeHUh?=
SK-HEP-1 MXvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4XQTmlEPTB;MUGuO|Y1PiEQvF2= MWLTRW5ITVJ?
BEN NUG1NnVGT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3HRPWlEPTB;MUGuPFUyKM7:TR?= MWXTRW5ITVJ?
NCI-H1770 Ml32S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3HsNGlEPTB;MUKuNVI3KM7:TR?= NVXKW3RoW0GQR1XS
SW13 NELWRW5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEToTmhKSzVyPUGyMlE2PDFizszN M{K0VXNCVkeHUh?=
MZ1-PC MYjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYDpW20zUUN3ME2xNk42PDV{IN88US=> MkX4V2FPT0WU
Mo-T MlrlS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIPvOZBKSzVyPUGyMlc1OjFizszN Mne2V2FPT0WU
HLE NF3GSGxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVjveoxFUUN3ME2xNk45OjF3IN88US=> MoTiV2FPT0WU
RCC10RGB M{nXZ2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Ml;yTWM2OD1zMz62O|Eh|ryP NWPhXYIyW0GQR1XS
COLO-320-HSR M2nhcWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoLiTWM2OD1zMz63N|gyKM7:TR?= NVfOVIZmW0GQR1XS
BHT-101 NXfSXFdvT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlXOTWM2OD1zMz64N|Q2KM7:TR?= NITNVoVUSU6JRWK=
OCUB-M M3z3S2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUHJR|UxRTF2LkG2NFIh|ryP NFTBeodUSU6JRWK=
MEG-01 NFzxdYdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NV3QSGlzUUN3ME2xOE4{PzB6IN88US=> NFzhPHdUSU6JRWK=
RS4-11 NXfvUpdzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFvTWJpKSzVyPUG0Mlc1OiEQvF2= MXLTRW5ITVJ?
MN-60 NETMO|BIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1O4XGlEPTB;MUSuO|g6PCEQvF2= NVX2RYdPW0GQR1XS
NCI-H1304 NGXtb4VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlO3TWM2OD1zNT6wOFI2KM7:TR?= MYPTRW5ITVJ?
Ramos-2G6-4C10 MmHFS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnnnTWM2OD1zNT6wOVgyKM7:TR?= MkizV2FPT0WU
NCI-H2342 MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYXJR|UxRTF3LkKwOFQh|ryP NHX6bWhUSU6JRWK=
LAN-6 M{DpVWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHXCPYRKSzVyPUG1MlQ1OTRizszN M1\3NnNCVkeHUh?=
JVM-2 M3n1U2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1jSUWlEPTB;MUWuOVc1QCEQvF2= NXPBXIdqW0GQR1XS
P30-OHK NF\P[I9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmnZTWM2OD1zNj6wOlE1KM7:TR?= M1TRXnNCVkeHUh?=
C-33-A MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXnBeFNRUUN3ME2xOk43OjF2IN88US=> MoLaV2FPT0WU
RPMI-8866 MlPWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVrVXGNCUUN3ME2xOk45PDl4IN88US=> M{\MXHNCVkeHUh?=
NCI-H630 NVLGNotPT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlXrTWM2OD1zNj64OVM4KM7:TR?= MUXTRW5ITVJ?
KYSE-140 M2myemdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoPsTWM2OD1zNz6yNFI5KM7:TR?= MVXTRW5ITVJ?
T84 MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWLJR|UxRTF6Lki2PVUh|ryP MlG5V2FPT0WU
KU-19-19 NU\kbmNET3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoXOTWM2OD1zOD65OlA5KM7:TR?= NV3PfIdJW0GQR1XS
BALL-1 NIKxN3BIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkDCTWM2OD1zOT6zN|k6KM7:TR?= NEfTZotUSU6JRWK=
Calu-6 M4HGbGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXjJR|UxRTF7LkS5NkDPxE1? MoLpV2FPT0WU
EGI-1 NX;TOVRST3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoLCTWM2OD1zOT61PVgh|ryP MnG3V2FPT0WU
MFH-ino MnPwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MW\JR|UxRTF7Lke0OVQh|ryP NIHFOJNUSU6JRWK=
GB-1 MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2ToZmlEPTB;MkCuN|U{PSEQvF2= MmXoV2FPT0WU
NCI-H1693 MoDBS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3viWWlEPTB;MkCuOlUxPSEQvF2= NVLEV4ppW0GQR1XS
SW1116 MYjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NELaVJdKSzVyPUKwMlk{PjJizszN NWLyc5NZW0GQR1XS
H-EMC-SS M4LmSWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4jzfmlEPTB;MkKuNFQ2KM7:TR?= MoS1V2FPT0WU
D-502MG M1vwfmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MV7JR|UxRTJ{LkiyOlEh|ryP M{TxdHNCVkeHUh?=
IA-LM NIDOS29Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4fEc2lEPTB;MkOuNlQ6OyEQvF2= MWDTRW5ITVJ?
SW1463 NWLSSHVGT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVTHRW16UUN3ME2yN{44QSEQvF2= NYTCXJRZW0GQR1XS
JAR M1X1S2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MV;JR|UxRTJ2LkOyPVMh|ryP NXfW[2c6W0GQR1XS
HT MYjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYfsSXNjUUN3ME2yOE41PzV|IN88US=> MkfiV2FPT0WU
LCLC-103H M4jLXmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFSyOIVKSzVyPUK0Mlg1PDlizszN MkC1V2FPT0WU
SNU-449 MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEfWVmxKSzVyPUK0Mlg4PDFizszN MmLlV2FPT0WU
KE-37 NUTxdGtbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWPWO4cyUUN3ME2yOU4xQTJ6IN88US=> MWTTRW5ITVJ?
NCI-H1623 Mn7mS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NF\z[XdKSzVyPUK3MlE{ODNizszN NWD3ZotxW0GQR1XS
MOLT-13 NHTZeYVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1nQVGlEPTB;MkeuN|UyPiEQvF2= M2ixSHNCVkeHUh?=
COLO-741 M{nhT2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4S4NmlEPTB;M{GuN|M{OyEQvF2= M1jHVXNCVkeHUh?=
NB6 M4TxXmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NECxeHNKSzVyPUOyMlI5PzZizszN M4f1U3NCVkeHUh?=
MOLT-16 MXjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NF7pdYdKSzVyPUOzMlAxPTVizszN NWfvNJYxW0GQR1XS
IST-MES1 NV:3dHBsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUC4OFdFUUN3ME2zOE4xPTRzIN88US=> NXjFOoxjW0GQR1XS
A4-Fuk NF;CR4tIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MW\JR|UxRTN3LkC2OkDPxE1? M3rXXnNCVkeHUh?=
CAL-85-1 M4K2XGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3f1PGlEPTB;M{WuNlgyPyEQvF2= MmrCV2FPT0WU
CCRF-CEM MoH5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGjGRpBKSzVyPUO3MlE2OzZizszN M1vITnNCVkeHUh?=
HAL-01 MknaS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWexe3V2UUN3ME2zPE41QDh7IN88US=> NFPHb5hUSU6JRWK=
HEL NH\YcXNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUjlfnRkUUN3ME20N{4{PDB7IN88US=> MmizV2FPT0WU
EW-1 NGqybHJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVfJR|UxRTR|LkS3Olgh|ryP NUGyXpBSW0GQR1XS
MDA-MB-231 Mnv0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NX;RSYk4UUN3ME20OU4yOTl7IN88US=> NX3W[Vc2W0GQR1XS
ABC-1 NWLhUokyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVPJR|UxRTR4Lki1N|gh|ryP MlHFV2FPT0WU
NCI-H446 Mk\mS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2iyOmlEPTB;NEiuOVA2QCEQvF2= M1XyeHNCVkeHUh?=
MHH-PREB-1 MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXXJR|UxRTR7Lk[wNFch|ryP M2e0eXNCVkeHUh?=
DOHH-2 NWrwPHpHT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYDJR|UxRTR7Lk[2OVYh|ryP MYPTRW5ITVJ?
GCT MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFm5OFdKSzVyPUS5MlY6PzZizszN NIC4PHFUSU6JRWK=

... Click to View More Cell Line Experimental Data

In vivo試験 17-AAG displays significantly higher binding affinity for Hsp90 from 3T3-src, B16 or CT26 xenografts in nude mice with IC50 values of 8-35 nM as compared with that from the normal tissues with IC50 values of 200-600 nM. [1] Administration of 17-AAG (~50 mg/kg) causes significant decline in AR, HER2, HER3, and Akt expression in a dose-dependent manner with >50% decline at dose of 50 mg/kg, resulting in the dose-dependent inhibition of androgen-dependent (CWR22) and -independent (CWR22R and CWRSA6) prostate cancer xenografts growth by 67%, 80% and 68% at dose of 50 mg/kg, respectively. [2]
臨床試験 A Phase II study of 17-AAG in patients with relapsed/refractory CD30 plus anaplastic large cell lymphoma (ALCL) relapsed/refractory mantle cell lymphoma (MCL) and relapsed/refractory classical Hodgkin's lymphoma (HL) has been completed.
特集 Displays very low toxicity toward normal cells.

プロトコル (参考用のみ)

キナーゼアッセイ: [1]

Hsp90 binding assays Purified native Hsp90 protein or cell lysates from HER-2-overexpressing cancer cells (BT474, N87, SKOV3 and SKBR3) or BT474 breast carcinoma cells in lysis buffer (20 mM HEPES, pH 7.3, 1 mM EDTA, 5 mM MgCl2, 100 mM KCl) are incubated with various concentrations of 17-AAG for 30 minutes at 4 °C, and then incubated with biotin-GM linked to BioMag streptavidin magnetic beads for 1 hour at 4 °C. Tubes are placed on a magnetic rack, and the unbound supernatant removed. The magnetic beads are washed three times in lysis buffer and heated for 5 minutes at 95 °C in SDS–PAGE sample buffer. Samples are analysed on SDS protein gels, and western blots done using indicated antibodies. Bands in the western blots are quantified using the Bio-rad Fluor-S MultiImager, and the percentage inhibition of binding of Hsp90 to the biotin-GM is calculated. The IC50 reported is the concentration of 17-AAG needed to cause half-maximal inhibition of binding.

細胞アッセイ: [1]

細胞株 BT474, SKBR3, N87, SKOV3, MCF7, MDA468, Hs578T, Hs578Bst, A549, HT29, U87, SKMG3, HT1080, RPTEC, NDF, HMVEC, HMEC, HUVEC, and PBMC cells
濃度 Dissolved in DMSO, final concentrations ~10 μM
反応時間 5 days
実験の流れ Cells are seeded in 96-well plates at 2,000 cells per well in a final culture volume of 100 μL for 24 hours before the addition of increasing concentrations of 17-AAG that is incubated for 5 days. Viable cell number is determined using the Celltiter 96 AQueous Nonradioactive Cell Proliferation Assay. The value of the background absorbance at 490 nm (A490) of wells not containing cells is subtracted. Percentage of viable cells = (A490 of 17-AAG treated sample/A490 untreated cells) × 100. The IC50 is defined as the concentration that gave rise to 50% viable cell number.

動物実験: [2]

動物モデル Male nu/nu athymic mice inoculated s.c. with androgen-dependent CWR22 xenograft, and female nu/nu athymic mice inoculated s.c. with androgen-independent xenografts CWR22R and CWRSA6
製剤 Dissolved in DMSO, and diluted in egg phospholipids (EPL) vehicle
投薬量 ~50 mg/kg
投与方法 Injection i.p.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)

SpeciesMouseRatRabbitGuinea pigHamsterDogMonkeyBaboon
Weight (kg)0.020.151.80.40.0810312
Body Surface Area (m2)0.0070.0250.150.050.020.50.240.6
Km factor361285201220
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Rat dose (mg/kg) = mouse dose (22.4 mg/kg) ×  mouse Km(3)  = 11.2 mg/kg
rat Km(6)
1

参考

化学情報

Download Tanespimycin (17-AAG) SDF
分子量 585.69
化学式

C31H43N3O8

CAS No. 75747-14-7
保管 3年-20℃
2年-80℃in solvent
別名 CP127374,NSC-330507, KOS 953
溶解度 (25°C) * In vitro DMSO 100 mg/mL (170.73 mM)
Ethanol 5 mg/mL (8.53 mM)
Water <1 mg/mL
In vivo 5%DMSO+corn oil 10mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
化学名 17-demethoxy-17-(2-propenylamino)- [(3R,5R,6S,7R,8E,10R,11R,12Z,14E)-6-Hydroxy-5,11,21-trimethoxy-3,7,9,15-tetramethyl-16,20,22-trioxo-17-azabicyclo[16.3.1]docosa-1(21),8,12,14,18-pentaen-10-yl] carbamate

文献中の引用 (19)

Frequently Asked Questions

  • Question 1
    What kind of subtypes does this compound inhibit? HSP90α or HSP90β ?

    Answer: 17-AAG can inhibit both HSP90α and HSP90β, but it is unclear how much are they affected respectively. You should note that Hsp90 derived from tumor cells has a 100-fold higher binding affinity for 17-AAG than that from normal cells according to this paper. http://www.nature.com.ezp-prod1.hul.harvard.edu/nature/journal/v425/n6956/full/nature01913.html

技術サポート&よくある質問(FAQ)

ストックの作り方、阻害剤の保管する方法、細胞実験や動物実験に注意すべきな点を全部含めており、製品を取扱う時よくあった質問に対して取扱説明書でお答えいたします。

電話番号: +1-832-582-8158 Ext:3月曜日〜金曜日 9:00 AM–5:00 PM (米国中部標準時)

他の質問がある場合は、お気軽くお問合せください。

* 必須

Related HSP (e.g. HSP90) 阻害剤

  • PU-H71

    PU-H71 is a potent and selective inhibitor of HSP90 with IC50 of 51 nM.

  • KNK437

    KNK437は1種のパン(pan)- HSP 阻害剤で、誘導HSPsの合成(HSP105、 HSP72,と HSP40を含める)を抑制します。

  • VER155008

    VER-155008 is a potent Hsp70 family inhibitor with IC50 of 0.5 μM, 2.6 μM, and 2.6 μM in cell-free assays for HSP70, HSC70, and GRP78, respectively, >100-fold selectivity over HSP90.

  • FRAX597

    FRAX597 is a potent, ATP-competitive inhibitor of group I PAKs with IC50 of 8 nM, 13 nM, and 19 nM for PAK1, PAK2, and PAK3, respectively.

  • Luminespib (AUY-922, NVP-AUY922)

    Luminespib (AUY-922, NVP-AUY922)は高度的に HSP90 を抑制、 HSP90α と HSP90β を作用すると、 IC50 がそれぞれ 13 nM 、 21 nM となる。

  • Ganetespib (STA-9090)

    Ganetespib (STA-9090)は独特な triazolone-containing Hsp90阻害剤、 IC50 が4 nM となる.

  • Alvespimycin (17-DMAG) HCl

    Alvespimycin (17-DMAG) HClは、62nMのIC50による強力なHsp90阻害剤です。

    Features:A synthetic derivative Geldanamycin, with lower hepatotoxicity than parent antibiotic & higher potency and bioavailability than the similar derivative 17-AAG.

  • Geldanamycin

    Geldanamycinは一種の天然なHSP90阻害剤で、Kd値が1.2μMですが、糖質ステロイド受容体(GR)/HSP連合を特異性的に妨害します。

  • HSP990 (NVP-HSP990)

    NVP-HSP990 (HSP990) is a novel, potent and selective HSP90 inhibitor for HSP90α/β with IC50 of 0.6 nM/0.8 nM.

    Features:NVP-HSP990 is an orally available HSP90 inhibitor and is structurally distinct from other clinical HSP90 inhibitors.

最近チェックしたアイテム

Tags: Tanespimycin (17-AAG)を買う | Tanespimycin (17-AAG)供給者 | Tanespimycin (17-AAG)を購入する | Tanespimycin (17-AAG)費用 | Tanespimycin (17-AAG)生産者 | オーダーTanespimycin (17-AAG) | Tanespimycin (17-AAG)代理店
×
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
お問い合わせ