5-HT Receptor

5-HT Receptor (53)

水溶性

目録号 製品名 情報 製品表彰状 カスタマーレビュー
S2459 Clozapine Clozapine is a potent 5-HT1C receptor antagonist with an IC50 of 110 nM for 5-HT-stimulated phosphoinositide hydrolysis.
S1488 Naratriptan Naratriptan is a triptan agent that is used for the treatment of migraine headaches.
S2493 Olanzapine Olanzapine is a high affinity for 5-HT2 serotonin and D2 dopamine receptor antagonist.
S1283 Asenapine Asenapine inhibits adrenergic receptor1, α2A, α2B, α2C) with Ki of 0.25-1.2 nM and also inhibits 5-HT receptor (1A, 1B, 2A, 2B, 2C, 5A, 6, 7) with Ki of 0.03-4.0 nM.
S1333 Fluoxetine HCl Fluoxetine HCl is an antidepressant of the selective serotonin reuptake inhibitor (SSRI)class.
S1441 Venlafaxine Venlafaxine is an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI).
S1607 Rizatriptan Benzoate Rizatriptan Benzoate is a 5-HT1 agonist triptan drug for the treatment of migraine headaches.
S8010 PRX-08066 Maleic acid PRX-08066 Maleic acidは、選択的な5-HT2B 敵対者で、IC50 が3.4 nMです。
S8021 Vortioxetine (Lu AA21004) HBr Vortioxetine (Lu AA21004) HBrは、経口多モード血清トン作動性薬剤で、 5-HT(1A)5-HT(1B)5-HT(3A)5-HT(7)SERTに作用すると、IC50がそれぞれ15 nM、33 nM、3.7 nM、19 nM、1.6 nMです。
S1243 Agomelatine Agomelatine is classified as a norepinephrine-dopamine disinhibitor (NDDI) due to its antagonism of the 5-HT2C receptor.
S1245 Latrepirdine Latrepirdine is an antihistamine drug.
S1336 Fluvoxamine maleate Fluvoxamine maleate is a selective serotonin (5-HT) reuptake inhibitor (SSRI)
S1345 Granisetron HCl Granisetron HCl is a serotonin 5-HT3 receptor antagonist
S1385 Mosapride Citrate Mosapride Citrate is a gastroprokinetic agent that acts as a selective 5HT4 agonist.
S1390 Ondansetron HCl Ondansetron HCl is a serotonin 5-HT3 receptor antagonist.
S1432 Sumatriptan Succinate Sumatriptan Succinate is a triptan sulfa drug containing a sulfonamide group for the treatment of migraine headaches.
S1436 Tianeptine sodium Tianeptine sodium is a selective serotonin reuptake enhancer (SSRE) compound used for treating major depressive episodes.
S1615 Risperidone Risperidone is an atypical antipsychotic used to treat schizophrenia.
S1869 Dapoxetine HCl Dapoxetine HCl is a short-acting novel selective serotonin reuptake inhibitor.
S1898 Tropisetron Tropisetron is a selective 5-HT3 receptor antagonist and α7-nicotinic receptor agonist with an IC50 of 70.1 ± 0.9 nM for 5-HT3 receptor.
S1649 Zolmitriptan Zolmitriptan is a selective serotonin receptor agonist.
S2232 Ketanserin Ketanserin is specific 5-HT2A serotonin receptor antagonist with a Ki of 2.5 nM for rat and human 5-HT2A.
S2541 Clomipramine HCl Clomipramine HCl is a hydrochloride salt of clomipramine which is a serotonin transporter (SERT), norepinephrine transporter (NET) dopamine transporter (DAT) blocker with Ki of 0.14, 54 and 3 nM, respectively.
S2663 WAY-100635 Maleate WAY-100635 Maleateは、0.95nMのIC50による5-HTのための強力で選択的な5-hydroxytryptamine1A拮抗剤です。
S2677 BRL-15572 BRL-15572は、7.9のpKiをもつセロトニン受容体サブタイプ5-HT1D敵対者です。
S2669 LY310762 LY310762は、中央0.2μMのKiによるモルモット5-HT1Dレセプターのための5-HT1Dセロトニン受容体拮抗剤です。
S1996 Ondansetron Ondansetron is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic.
S2582 Trazodone HCl Trazodone HCl is an antidepressant belonging to the class of serotonin receptor antagonists and reuptake inhibitors for treatment of anxiety disorders.
S2698 RS-127445 RS-127445は、pKi==9.5±0.1とpIC50 =10.4±0.1による選択性の高いオートフォーカスfi死亡率が高い5-HT2B受容体拮抗剤です。
S2025 Urapidil HCl Urapidil HCl is a hydrochloride salt form of urapidil which is α1-adrenoceptor antagonist and 5-HT1A receptor agonist with pIC50 of 6.13 and 6.4 respectively.
S1975 Aripiprazole Aripiprazole is a human 5-HT1A receptor partial agonist with a Ki of 4.2 nM.
S2084 Duloxetine HCl Duloxetine HCl is a serotonin-norepinephrine reuptake inhibitor with Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD).
S2106 Azasetron HCl Azasetron HCl is a selective 5-HT3 receptor antagonist with IC50 of 0.33 nM used in the management of nausea and vomiting induced by cancer chemotherapy.
S2096 Almotriptan Malate Almotriptan Malate is a selective 5-hydroxytryptamine1B/1D (5-HT1B/1D) receptor agonist, used for the treatment of Migraine attacks in adults.
S2112 Blonanserin Blonanserin is a novel atypical antipsychotic agent with potent dopamine D2 (Ki, 14.8 nM) and serotonin 5-HT2(Ki, 3.98 nM) receptors antagonist properties.
S3005 Paroxetine HCl Paroxetine HCl is an antidepressant drug of the SSRI type.
S3024 Lamotrigine ラモトリジンは、240μMと474μMのIC50によるヒト血小板とネズミ脳シナプトソームの5-ヒドロキシトリプタミン(5-HT)取り込みの抑制のための新しい抗痙攣剤です。
S3175 Atomoxetine HCl Atomoxetine HCl is a selective norepinephrine (NE) transporter inhibitor with Ki of 5 nM, with 15- and 290-fold lower affinity for human 5-HT and DA transporters.Phase 4.
S3180 Eletriptan HBr Eletriptan HBr is a selective 5-HT1B and 5-HT1D receptor agonist with Ki of 0.92 nM and 3.14 nM, respectively.
S3183 Amitriptyline HCl Amitriptyline HCl inhibits serotonin receptor, norepinephrine receptor, 5-HT4, 5-HT2 and sigma 1 receptor with IC50 of 3.45 nM, 13.3 nM, 7.31 nM, 235 nM and 287 nM, respectively.
S2860 IEM 1754 dihydrobroMide IEM 1754 dihydrobroMide is a selective AMPA/kainate receptor blockers for GluR1 and GluR3 with IC50 of 6 μM.
S2852 BRL-54443 BRL-54443 is a 5-HT1E and 5-HT1F receptor agonist with pKi of 8.7 and 9.25, respectively.
S2849 SB269970 HCl SB269970 HCl is a hydrochloride salt form of SB-269970, which is a 5-HT7 receptor antagonist with pKi of 8.3.
S3050 Palonosetron HCl Palonosetron HCl is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting.
S2865 VUF 10166 VUF 10166 is a novel, potent and competitive antagonist for 5-HT3A receptor with Ki of 0.04 nM, its affinity at 5-HT3AB receptor is significantly lower.
S2875 Prucalopride Prucalopride is a selective, high affinity 5-HT receptor agonist for 5-HT4A and 5-HT4B receptor with Ki of 2.5 nM and 8 nM, respectively, exhibits >290-fold selectivity against other 5-HT receptor subtypes. Phase 3.
S2856 SB271046 SB271046 is a potent, selective and orally active 5-HT6 receptor antagonist with pKi of 8.9, exhibits 200-fold greater selectivity over other 5-HT receptor subtypes.
S2894 SB742457 SB742457 is a highly selective 5-HT6 receptor antagonist with pKi of 9.63, exhibits >100-fold selectivity over other receptors. Phase 2.
S4053 Sertraline HCl Sertraline HCl is a 5-HT inhibitor with Ki of 13 nM.
S4064 Escitalopram Oxalate Escitalopram Oxalateは、選択的なセロトニン(5-HT)再摂取阻害剤(SSRI)で、Ki が0.89 nMです。
S4109 Lorcaserin HCl Lorcaserin HClが人間 5-HT2Cの選択フルアゴニスト受容体で、Ki が15 nMです。
S4112 Desvenlafaxine Succinate Desvenlafaxine Succinateは、新規の セロトニン(5-HT) のトランスポーターと ノルエピネフリン(NE) のトランスポーターが再取り込み阻害剤で、Ki がそれぞれ 40.2 nM と 558.4 nM です。
S4113 Desvenlafaxine Desvenlafaxineは セロトニン(5-HT)ノルエピネフリン(NE)の再取り込み阻害剤で、Ki がそれぞれ40.2 nM と 558.4 nMです。