P450 (e.g. CYP17)

  • P450 (e.g. CYP17)製品生物活性の比較
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P450 (e.g. CYP17) 阻害剤 (24)

水溶性

製品コード 製品名称 製品説明 文献中の引用 お客様のフィードバック
S1123 Abiraterone Abirateroneは、2nMのIC50による強力なCYP17阻害剤です。
S2246 Abiraterone Acetate Abiraterone Acetate は、72nMのIC50によるステロイドのシトクロムP450 17alpha-ヒドロキシラーゼ-17,20-リアーゼ(CYP17)阻害剤であるAbirateroneのアセテート塩の形です。
S1442 Voriconazole Voriconazole is a triazole antifungal medication that is generally used to treat serious, invasive fungal infections.
S2187 Avasimibe Avasimibe は、ACATとP450イソ酵素CYP2C9を妨げます。IC50 がそれぞれ 3.3 μM と 2.9 μMです。
S1353 Ketoconazole Ketoconazole(合成イミダゾール抗真菌物質)は、表在性真菌感染のために効果的です。
S2476 Itraconazole Itraconazole is a triazole antifungal agent.
S1331 Fluconazole Fluconazole is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections.
S2268 Baicalein Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor.
S2262 Apigenin Apigenin is a potent CYP2C9 inhibitor with an IC50 of 23 pM.
S2344 Piperine Piperine is the alkaloid responsible for the pungency of black pepper and long pepper, along with chavicine (an isomer of piperine). It has also been used in some forms of traditional medicine and as an insecticide.
S2380 Diosmetin Diosmetin is a bioflavonoid found in spearmint, oregano, and many other plants.
S2803 Galeterone Galeteroneは、選択的なCYP17阻害剤とアンドロゲン受容体(AR)敵対者で、IC50 がそれぞれ 300 nM と 384 nMです。
S2394 Naringenin Naringenin is a flavonoid that is considered to have a bioactive effect on human health as antioxidant, free radical scavenger, anti-inflammatory, carbohydrate metabolism promoter, and immune system modulator.
S4221 Benzbromarone Benzbromarone is a CYP2C9 inhibitor, it binds to CYP2C9 with Ki value of 19.3 nM.
S2555 Clarithromycin Clarithromycin is a macrolide antibiotic and a CYP3A4 inhibitor.
S2900 Cobicistat (GS-9350) Cobicistat(GS-9350)は、CYP3Aの強力で選択的な阻害剤で、IC50 が30-285 nMです。
S2921 PF-4981517 PF-4981517は、CYP3A4の強力で選択的な阻害剤で、IC50 が 0.03 µMです。
S2067 Ozagrel HCl Ozagrel HCl is a selective thromboxane A2 synthetase enzyme inhibitors with IC50 of 11 nM, used as antiasthmatic agent.
S2496 Ozagrel Ozagrel is a selective thromboxane A(2) (TXA(2)) synthetase inhibitor with IC50 of 11 nM for rabbit platelet, used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral ischaemia.
S1195 TAK-700 (Orteronel) TAK-700(Orteronel)は、有力で非常に選択的なネズミと人間の17,20-リアーゼ阻害剤で、IC50 がそれぞれ 54 nM と 38 nMです。
S2046 Pioglitazone HCl Pioglitazone HCl is a selective peroxisome proliferator-activated receptor-gamma (PPARgamma) agonist, used to treat diabetes.
S2526 Alizarin リザリンは、P450アイソフォームCYP1A1、CYP1A2とCYP1B1を強く妨げまして、 IC50 がそれぞれ 6.2 μM、 10.0 μM、2.7 μMです。
S2401 Sodium Danshensu Sodium Danshensu is a mono sodium of danshensu which is a compound isolated from Salvia miltiorrhiza Bge.
S2329 Naringin Naringin is a flavanone glycoside and is a major flavonoid in grapefruit and gives the grapefruit juice its bitter taste.
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